Lactones
eMolecules 2-Acetylbutyrolactone | 517-23-7 | MFCD00005394 | 5g
Combi-Blocks | 2-Acetylbutyrolactone | 5g | 335346054 | QE-5636 | 95.000 | 517-23-7 | MFCD00005394 | 128.127 | C6H8O3
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eMolecules Pharmablock / benzyl (3R)-3-(hydroxymethyl)piperazine-1-carboxylate / 25mg / 586142134 / PB91086 / 0.000 / 930837-03-9 / MFCD09954308 / 250.298 / C13H18N2O3
Pharmablock / benzyl (3R)-3-(hydroxymethyl)piperazine-1-carboxylate / 25mg / 586142134 / PB91086 / 0.000 / 930837-03-9 / MFCD09954308 / 250.298 / C13H18N2O3
Medchemexpress LLC AMPK gamma 1 Antibody (YA621) | 38 kDa | 100 UL
This AMPK gamma 1 Antibody (YA621) is a rabbit-derived, non-conjugated IgG monoclonal antibody, targeting to AMPK gamma 1. It is formulated in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol and 0.05% BSA, with 0.01% Sodium azide as a preservative. This antibody is suitable for Western Blot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), and Immunoprecipitation (IP) applications, and has a concentration of 0.5 mg/mL. The predicted and observed molecular weight is 38 kDa. It is reactive with human samples.
- Rabbit-derived and non-conjugated IgG monoclonal antibody
- Targets AMPK gamma 1
- Suitable for Western Blot, ICC/IF, and Immunoprecipitation
- Concentration of 0.5 mg/mL
- Predicted and observed molecular weight: 38 kDa
- Reactivity: Human
- Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Medchemexpress LLC IFN-gamma R1/CD119 2ug
IFN-gamma R1 (CD119) one of the subunit of IFN-gamma receptor is a receptor for IFN-gamma IFN-gamma R1 forms the functional receptor with IFN-gamma R2 Upon binding with IFN-gamma IFN-gamma R1 and IFN-gamma R2 oligomerize and transphosphorylate[1] Then JAK1 and JAK2 are phosphorylated and activated and STAT1 is recruited to the receptor complex Phosphorylated STAT1 translocates to the nucleus where it regulates the expression of IFN-responsive genes (e g CD54)[2] IFN-gamma R1/CD119 Protein Human (228a a HEK293 His) is a recombinant human IFN-gamma R1 (E18-G245) with C-terminal 6 His tag which is produced in HEK293 cells
Selleck Chemical LLC GA-017-E1145-25MG
GA-017 inhibits the serine/threonine protein kinases large tumor suppressor kinase 1/2 (LATS1/2) which exerts inhibitory with IC50s against LATS1 and 2 of 4 10 0 79 and 3 92 0 42 nM respectively and competitively inhibits LATS1 and 2 against ATP with Ki (inhibition constant) values of 0 58 0 11 and 0 25 0 03 nM respectively
Cell Signaling Technology IFN-gamma (D3H2) XP(R) Rabbit mAb 20 ul
IFN-gamma (D3H2) XP(R) Rabbit mAb 20 ul
Medchemexpress LLC Gamma-glutamylcysteine TFA | 283159-88-6 | 95.2% | 364.30 | 10 MG
Gamma-glutamylcysteine TFA is an orally active, blood-brain barrier permeable dipeptide involved in regulating macrophage polarization, inducing glutathione synthesis, and improving metabolic dysfunction. It is relevant for research in various diseases.
- Orally active and blood-brain barrier permeable dipeptide.
- Activates AMPK, SIRT1, IL-4/STAT6, AC/cAMP/PI3K, IGF-1R/IRS1/PI3K, and Nrf2 signaling pathways.
- Inhibits NF-κB, JAK1/STAT1/3, MAPKs, and PI3K/Akt signaling pathways.
- Regulates macrophage polarization and modulates CD36 and GLUT4 trafficking.
- Induces glutathione synthesis, improves metabolic dysfunction, and ameliorates glucose homeostasis.
- Reduces lipid deposition, inhibits apoptosis, stabilizes mitochondria, and suppresses ferroptosis.
- Relevant for research in inflammatory bowel disease, type 2 diabetes, Alzheimer's disease, and alcoholic liver disease.
Medchemexpress LLC Gamma catenin antibody (YA3801) | 82 kDa | 50 UL
This gamma Catenin Antibody (YA3801) is a mouse-derived, non-conjugated IgG1 monoclonal antibody targeting gamma Catenin. It is affinity purified and supplied in PBS with 0.05% sodium azide. Gamma catenin is a common junctional plaque protein that plays a key role in cytoskeletal organization and cellular function within tissues, influencing the structure and function of submembranous plaques.
- Suitable for research applications
- Reacts with human samples
- Predicted and observed molecular weight is 82 kDa
- Applications include WB, IHC-P, ICC/IF, and ELISA
- Stored at -20°C for 1 year
- Avoid repeated freeze/thaw cycles
Indofine Chemical 6-HYDROXYFLAVANONE, Flavonoid & Coumarins, 4250-77-5, 0.99, 250 mg
6-HYDROXYFLAVANONE, Flavonoid & Coumarins, 4250-77-5, 0.99, 250 mg
Medchemexpress LLC gamma-Glutamylarginine | 31106-03-3 | 303.31 | 100 MG
gamma-Glutamylarginine (L-γ-Glutamyl-L-arginine) is an γ-glutamic acid oligopeptide that can be isolated from Panax ginseng. It is intended for research use only.
- An γ-glutamic acid oligopeptide
- Can be isolated from Panax ginseng
- For research use only
Medchemexpress LLC Fc gamma RIIB/CD32b protein, rat (recombinant, HEK293, His tag) | 50 UG
Recombinant rat Fc gamma RIIB/CD32b extracellular domain produced in HEK293 cells with a C-terminal His tag. Supplied as a purified recombinant protein for biochemical and immunological research, including Fc receptor binding, antibody-Fc interaction studies, and cell signaling assays. Follow supplier storage and handling recommendations.
- Recombinant extracellular domain of Fc gamma RIIB/CD32b, rat.
- Expressed in HEK293 mammalian cells.
- C-terminal His tag for purification and detection.
- Supplied in research-scale quantities (e.g., 50 μg).
- Suitable for binding assays and signaling studies.
Medchemexpress LLC IFN-gamma protein, human (CHO) | >95.0% | 100UG
IFN-gamma Protein, Human (CHO) is a recombinant human cytokine produced in Chinese hamster ovary (CHO) cells and supplied as a lyophilized, tag-free protein for research use. It is intended for studies of immune signaling, antiviral responses, and cell-based bioassays, and is provided with supporting documentation including a safety data sheet and certificate of analysis.
- Recombinant human interferon-gamma expressed in CHO cells.
- Tag free, lyophilized formulation with trehalose stabilizer.
- High purity (>95%) as determined by reducing SDS-PAGE.
- Apparent molecular weight ~15-25 kDa due to glycosylation.
- Characterized bioactivity with low-nanogram ED50 in standard assays.
- Stable when stored at -20°C; aliquot and freeze at -80°C for long-term storage.
- Includes SDS and COA documentation for quality and safety.
Medchemexpress LLC IFN-gamma Mouse HE 100ug
Recombinant mouse interferon-gamma (IFN-γ) expressed in HEK293 cells, provided as a lyophilized powder for laboratory research. The product is >95% pure by reducing SDS-PAGE, has low endotoxin (<1 EU/μg), and shows potent biological activity in cell-based assays; follow the manufacturer's reconstitution and storage recommendations for optimal performance.
- HEK293-expressed recombinant protein suitable for in vitro studies.
- Lyophilized formulation for long-term storage and transport.
- High purity (>95%) as determined by reducing SDS-PAGE.
- Low endotoxin level (<1 EU/μg) for sensitive assays.
- Demonstrated biological activity with ED50 in the low ng/mL range.
- Stable when stored frozen and after reconstitution with recommended buffers.
Medchemexpress LLC Gamma-secretase modulator 2 | 1093978-89-2 | 98.8% | C25H22F4N6O2 | 1 ML
Gamma-secretase modulator 2 is a potent and selective gamma-secretase modulator. It is used for the study of Alzheimer's disease and is intended for research use only.
- Potent and selective gamma-secretase modulator
- Appears as a solid
- Color is white to off-white
- Soluble in DMSO at 100 mg/mL
- Useful for research in neurological and neurodegenerative diseases