Lactones
Medchemexpress LLC Gamma Catenin Antibody (YA420) | affinity purified | 82 kDa | 100UL
Gamma Catenin Antibody (YA420) is a rabbit-derived, non-conjugated IgG monoclonal antibody targeting gamma Catenin. This protein is a major cytoplasmic component common to submembranous plaques of both desmosomes and intermediate junctions. It forms distinct complexes with cadherins and desmosomal cadherins and is part of the catenin family, featuring an armadillo repeat motif. Mutations in this gene are associated with Naxos disease.
- Host: Rabbit
- Reactivity: Human
- Conjugation: Non-conjugated
- Research field: Signal transduction
- Formulation: Supplied in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol and 0.05% BSA. Preservative: 0.01% Sodium azide
- Appearance: Liquid
- Shipping: Shipping with blue ice
Medchemexpress LLC CCL9/10/MIP-1 gamma 2ug | 2ug
CCL9 Protein Mouse is often produced in macrophages osteoclasts and functions as a cell survival factor
Medchemexpress LLC IL-36 gamma/IL-1F9 2ug
Recombinant human IL-36 gamma (IL-1F9) is a lyophilized cytokine produced in E. coli for research use. The protein induces IL-8 secretion in A431 epithelial cells (ED50 5-20 ng/mL) and is supplied lyophilized from 20 mM Tris-HCl, 100 mM NaCl, 0.1 mM EDTA, pH 8.0. Recommended storage is -20°C, with aliquots at -80°C for extended storage; reconstitution and carrier protein guidance are provided for stability.
- Contains the human mature sequence S18-D169.
- Low endotoxin level (<1 EU/μg) suitable for bioassays.
- Lyophilized powder for convenient storage and transport.
- Formulated in Tris-HCl with NaCl and EDTA, pH 8.0.
- Demonstrated biological activity: ED50 5-20 ng/mL in A431 cells.
- Reconstitution guidance provided; not recommended below 100 μg/mL and carrier protein advised for long-term stability.
Medchemexpress LLC IFN-gamma Mouse HE 100ug
Recombinant mouse interferon-gamma (IFN-γ) expressed in HEK293 cells, provided as a lyophilized powder for laboratory research. The product is >95% pure by reducing SDS-PAGE, has low endotoxin (<1 EU/μg), and shows potent biological activity in cell-based assays; follow the manufacturer's reconstitution and storage recommendations for optimal performance.
- HEK293-expressed recombinant protein suitable for in vitro studies.
- Lyophilized formulation for long-term storage and transport.
- High purity (>95%) as determined by reducing SDS-PAGE.
- Low endotoxin level (<1 EU/μg) for sensitive assays.
- Demonstrated biological activity with ED50 in the low ng/mL range.
- Stable when stored frozen and after reconstitution with recommended buffers.
Medchemexpress LLC IFN-gamma R1/CD119 100ug
IFN-gamma R1 (CD119) one of the subunit of IFN-gamma receptor is a receptor for IFN-gamma IFN-gamma R1 forms the functional receptor with IFN-gamma R2 Upon binding with IFN-gamma IFN-gamma R1 and IFN-gamma R2 oligomerize and transphosphorylate[1] Then JAK1 and JAK2 are phosphorylated and activated and STAT1 is recruited to the receptor complex Phosphorylated STAT1 translocates to the nucleus where it regulates the expression of IFN-responsive genes (e g CD54)[2] IFN-gamma R1/CD119 Protein Mouse (HEK293 His) is a recombinant mouse IFN-gamma R1 with C-terminal 6 His tag which is produced in HEK293 cells
Medchemexpress LLC TC-G-1008 | 1621175-65-2 | 99.4% | 418.90 | C18H19ClN6O2S | 10 MG
TC-G-1008 (GPR39-C3) is a small-molecule, orally available agonist of the G protein-coupled receptor GPR39, supplied as a high-purity solid for in vitro and in vivo pharmacology. It exhibits sub-nanomolar potency (EC50 0.4 nM in rat, 0.8 nM in human) and is suitable for receptor pharmacology, target validation, and pharmacodynamic studies.
- Molecular formula: C18H19ClN6O2S
- Molecular weight: 418.90
- Purity: 99.4%
- Physical form: solid (powder)
- Solubility: DMSO ≥100 mg/mL; in vivo formulations ≥2.5 mg/mL
- Suggested storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (2 years)
- Available pack sizes: 5 mg, 10 mg, 25 mg, 50 mg, 100 mg
Medchemexpress LLC Fc gamma RIII/CD16 50ug | 50ug
The Fc gamma RIII/CD16 protein is a receptor for IgG and is optimally activated upon binding to aggregated antigen-IgG complexes initiating antibody-dependent cellular cytotoxicity (ADCC) and preventing inappropriate effector cell activation It mediates IgG effector functions on NK cells generating memory-like adaptive NK cells to efficiently eliminate virally infected cells Fc gamma RIII/CD16 Protein Rhesus Macaque (HEK293 His) is the recombinant Rhesus Macaque-derived Fc gamma RIII/CD16 protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC Glucosylceramide (gaucher's spleen) | 85305-87-9 | 98% | 1 MG
Glucosylceramides are sphingolipid molecules found in both neuronal and non-neuronal mammalian tissues, as well as in low quantities across various plant species. Elevated levels of glucosylceramides provide cellular protection and prepare certain cells for proliferation; however, they have also been linked to obesity-induced insulin resistance in mice and to neuronal deficits observed in neuronopathic Gaucher disease.
- Provides cellular protection
- Prepares certain cells for proliferation
Medchemexpress LLC IFN-gamma R1/CD119 2ug
IFN-gamma R1 (CD119) one of the subunit of IFN-gamma receptor is a receptor for IFN-gamma IFN-gamma R1 forms the functional receptor with IFN-gamma R2 Upon binding with IFN-gamma IFN-gamma R1 and IFN-gamma R2 oligomerize and transphosphorylate[1] Then JAK1 and JAK2 are phosphorylated and activated and STAT1 is recruited to the receptor complex Phosphorylated STAT1 translocates to the nucleus where it regulates the expression of IFN-responsive genes (e g CD54)[2] IFN-gamma R1/CD119 Protein Mouse (HEK293 His) is a recombinant mouse IFN-gamma R1 with C-terminal 6 His tag which is produced in HEK293 cells
Sigma Aldrich Fine Chemicals Biosciences gamma Dodecalactone natura1KG
gamma Dodecalactone natura1KG
Sigma Aldrich Fine Chemicals Biosciences Pilocarpine hydrochloride >=99% (titration), powder | 54-71-7 | MFCD00012722 | 10G
Pilocarpine hydrochloride >=99% (titration), powder | Purity: >=99% (titration) | Mol Wt: 244.72 | 54-71-7 | MFCD00012722 | 10G