Lactones
![Medchemexpress LLC Pyrido[2,1-c][1,4]oxazin-6(1H)-one derivative, 3,4,5-trifluorophenyl substituted | 937812-80-1 | 99.8% | 483.48 g/mol | C26H24F3N3O3 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000298650.png-250.jpg)
Medchemexpress LLC Pyrido[2,1-c][1,4]oxazin-6(1H)-one derivative, 3,4,5-trifluorophenyl substituted | 937812-80-1 | 99.8% | 483.48 g/mol | C26H24F3N3O3 | 10 MG
gamma-Secretase modulator for research applications. This small-molecule modulator inhibits amyloid-β production and is supplied as a high-purity white to off-white solid for laboratory use. It is intended for in vitro and preclinical research on γ-secretase-related pathways and Alzheimer's disease mechanisms.
- Used to modulate amyloid-β production in research assays.
- High reported purity suitable for analytical and biological studies.
- Defined molecular weight and formula for reproducible experiments.
- White to off-white solid, easy to handle and store.
- Available in small research quantities (e.g., 10 mg) for assay development.
Medchemexpress LLC Recombinant human AP-2 gamma (TFAP2C), His-tag | >95.0% | 5 UG
Recombinant human AP-2 gamma (TFAP2C) is provided as a His-tagged protein fragment for research use. Supplied as a 5 μg aliquot, the material is characterized by greater than 95.0% purity by reducing SDS-PAGE and is intended for applications such as antibody validation, binding studies, and assay development. Not for human or clinical use.
- His-tag facilitates purification and detection.
- Greater than 95.0% purity as determined by reducing SDS-PAGE.
- Supplied in a 5 μg quantity suitable for small-scale experiments.
- Derived from the human TFAP2C sequence for biologically relevant assays.
- Suitable for western blot, ELISA, and antibody validation workflows.
Apexbio Technology LLC Butyrolactone 3 778649-18-6 5mg
Butyrolactone 3 (CAS 778649-18-6) is a small-molecule inhibitor that targets the histone acetyltransferase Gcn5 a member of the GNAT family with specificity for histone H3 acetylation In vitro studies demonstrate that Butyrolactone 3 inhibits Gcn5 activity with an IC50 of 100 M while showing minimal inhibition of CBP The binding affinity of Butyrolactone 3 to Gcn5 is comparable to that of histone H3 and its inhibition is non-irreversible indicating it does not act via a Michael addition mechanism Structurally modification at position 2 has been suggested as a basis for structure activity relationship (SAR) studies Currently Butyrolactone 3 is utilized in preclinical research aimed at modulating Gcn5-mediated histone acetylation
Selleck Chemical LLC ATN-161
ATN-161 is a novel small peptide antagonist of integrin 5 1 It binds to several integrins including 5 1 and v 3 that play a role in angiogenesis and tumor progression
Medchemexpress LLC Butyrolactone 3 (MB-3) | 778649-18-6 | 99.6% | 10 MG
Butyrolactone 3 (MB-3) is a specific small-molecule inhibitor of the histone acetyltransferase Gcn5, with an IC50 of 100 μM. It demonstrates high affinity for the Gcn5 enzyme, similar to its natural substrate, histone H3, and shows weak inhibition of CBP (IC50 = 0.5 mM). This compound is suitable for studies related to cancer, metabolic, autoimmune, and neurological diseases.
- Specific small-molecule inhibitor of histone acetyltransferase Gcn5
- High affinity for the Gcn5 enzyme
- Weak inhibition of CBP
- Can be used in studies of cancer, metabolic, autoimmune, and neurological diseases
Selleck Chemical LLC ATN-161
ATN-161 is a novel small peptide antagonist of integrin 5 1 It binds to several integrins including 5 1 and v 3 that play a role in angiogenesis and tumor progression
Medchemexpress LLC Butyrolactone 3 | 778649-18-6 | 99.6% | 50 MG
Butyrolactone 3 (MB-3) is a specific small-molecule inhibitor of the histone acetyltransferase Gcn5, with an IC50 of 100 μM. It exhibits high affinity for the Gcn5 enzyme, similar to its natural substrate, histone H3, and shows weak inhibitory effects on CBP (IC50=0.5 mM). This compound is intended for research use only and is utilized in studies related to cancer, metabolic, autoimmune, and neurological diseases.
- Specific small-molecule inhibitor of histone acetyltransferase Gcn5
- Exhibits high affinity for Gcn5 enzyme
- Shows weak inhibitory effects on CBP
- Suitable for research in cancer, metabolic, autoimmune, and neurological diseases
AdipoGen Butyrolactone I
Chemical. CAS 87414-49-1. Formula C24H24O7. MW 424.5. Isolated from Aspergillus terreus. Cell permeable, potent and selective cyclin-dependent kinase CDK-1 CDC2, -2 and -5 inhibitor. Apoptosis inducer. Antitumor agent. Inhibits cell cycle progression at the G1/S and G2/M transitions. Shown to prevent the phosphorylation of retinoblastoma protein and H1 histone. Important probe for understanding the cellular roles of CDKs. Inhibitor of alpha-glucosidases. Maturation inhibitor of sheep oocytes.
Apexbio Technology LLC Butyrolactone 3 778649-18-6 1mg
Butyrolactone 3 (CAS 778649-18-6) is a small-molecule inhibitor that targets the histone acetyltransferase Gcn5 a member of the GNAT family with specificity for histone H3 acetylation In vitro studies demonstrate that Butyrolactone 3 inhibits Gcn5 activity with an IC50 of 100 M while showing minimal inhibition of CBP The binding affinity of Butyrolactone 3 to Gcn5 is comparable to that of histone H3 and its inhibition is non-irreversible indicating it does not act via a Michael addition mechanism Structurally modification at position 2 has been suggested as a basis for structure activity relationship (SAR) studies Currently Butyrolactone 3 is utilized in preclinical research aimed at modulating Gcn5-mediated histone acetylation
eMolecules 87414-49-1 | Medchem Express | Butyrolactone I | 1mg | 784543713 | HY-111237 | 424.449 | C24H24O7
Medchem Express | Butyrolactone I | 1mg | 784543713 | HY-111237 | 87414-49-1 | 424.449 | C24H24O7
Medchemexpress LLC 11-Keto-beta-boswellic acid | 17019-92-0 | 470.68 | 1 ML
11-Keto-beta-boswellic acid is a pentacyclic triterpenic acid derived from the oleogum resin of the Boswellia serrata tree, commonly known as Indian Frankincense. It possesses anti-inflammatory activity primarily by inhibiting 5-lipoxygenase (5-LOX) and subsequently leukotriene and nuclear factor-kappa B (NF-κB) activation and tumor necrosis factor alpha generation production.
- Anti-inflammatory activity
- Anti-diabetic activity observed in streptozotocin-induced diabetic rats
- Protects rats against kainic acid-induced excitotoxicity
- Solid, white to off-white appearance
Aobchem 2-Bromo-3-methyl-5-(hydroxymethyl)pyridine | ≥97% | CAS 1310416-58-0 | C7H8BrNO | 500mg
2-Bromo-3-methyl-5-(hydroxymethyl)pyridine | ≥97% | CAS 1310416-58-0 | C7H8BrNO | 500mg
Aobchem 5-Bromo-2-chloro-3-(hydroxymethyl)pyridine | ≥95% | CAS 742100-75-0 | C6H5BrClNO | 1g
5-Bromo-2-chloro-3-(hydroxymethyl)pyridine | ≥95% | CAS 742100-75-0 | C6H5BrClNO | 1g
Aobchem 2-Bromo-3-methyl-5-(hydroxymethyl)pyridine | ≥97% | CAS 1310416-58-0 | C7H8BrNO | 10g
2-Bromo-3-methyl-5-(hydroxymethyl)pyridine | ≥97% | CAS 1310416-58-0 | C7H8BrNO | 10g