accessibility menu, dialog, popup

UserName
Viewing profile as user:

Lactones

Organic heterocyclic compounds that consist of cyclic carboxylic esters and one or more heteroatoms replacing carbon atoms in the ring.

Filtered Search Results

Products from some of our suppliers do not display in filtered search results. Please clear all filters to see these products.

Narrow Results

Narrow Results

category

brands

  • (1)
  • (10)
  • (3)
  • (1)

special interests

  • (17)
Search Within Results
Keyword Search:
1 – 15 of 18 results
1

Medchemexpress LLC AMPK gamma 1/beta 2/alpha 2 heterotrimer protein | >90.0% | 10 UG
SDP

Recombinant human AMPK gamma 1/beta 2/alpha 2 heterotrimer protein produced in Sf9 insect cells with N-terminal His and GST tags. Supplied as a 0.22 μm filtered solution in Tris-NaCl buffer with stabilizers, the protein shows high purity and measurable kinase activity suitable for biochemical assays and structural studies. Store frozen and avoid repeated freeze-thaw cycles.

  • Recombinant heterotrimeric AMPK composed of gamma 1, beta 2, and alpha 2 subunits.
  • Expressed in Sf9 insect cells for eukaryotic folding and post-translational processing.
  • N-terminal His and GST tags for affinity purification and detection.
  • Purity greater than 90% as determined by reducing SDS-PAGE.
  • Supplied in a stabilized buffer formulation containing Tris, NaCl, EDTA, DTT, glycerol, and antioxidants.
  • Specific activity of 1-6 nmol/min/mg measured using SAMS peptide.
  • Available in small aliquots to minimize freeze-thaw and preserve activity.

ENCOMPASS_PREFERRED
2

Medchemexpress LLC AMPK gamma 1/beta 2/alpha 1 heterotrimer protein, human | 96.3% | 10 UG
SDP

Recombinant human AMPK α1β2γ1 heterotrimer protein expressed in Sf9 insect cells with an N-terminal His-GST tag. Supplied as a purified recombinant complex for in vitro kinase assays, biochemical characterization, and screening of modulators that affect AMPK activity.

  • Expressed in Sf9 insect cells with an N-terminal His-GST tag.
  • Purity approximately 96.3%.
  • Subunit molecular weights approx. 95 kDa (α1), 37 kDa (β2), 35 kDa (γ1).
  • Validated for in vitro kinase assays and biochemical profiling.
  • Supplied in microgram quantities suitable for biochemical assays.

ENCOMPASS_PREFERRED
3

eMolecules​ AstaTech / TERT-BUTYL 2-(HYDROXYMETHYL)-5-OXOPYRROLIDINE-1-CARBOXYLATE / 0.25g / 386413500 / F51783 / 95.000 / 344884-10-2 / MFCD24532043 / 215.249 / C10H17NO4

AstaTech / TERT-BUTYL 2-(HYDROXYMETHYL)-5-OXOPYRROLIDINE-1-CARBOXYLATE / 0.25g / 386413500 / F51783 / 95.000 / 344884-10-2 / MFCD24532043 / 215.249 / C10H17NO4

ENCOMPASS_PREFERRED
4

Medchemexpress LLC TC-G-1008 | 1621175-65-2 | 99.4% | 418.90 | C18H19ClN6O2S | 10 MG
SDP

TC-G-1008 (GPR39-C3) is a small-molecule, orally available agonist of the G protein-coupled receptor GPR39, supplied as a high-purity solid for in vitro and in vivo pharmacology. It exhibits sub-nanomolar potency (EC50 0.4 nM in rat, 0.8 nM in human) and is suitable for receptor pharmacology, target validation, and pharmacodynamic studies.

  • Molecular formula: C18H19ClN6O2S
  • Molecular weight: 418.90
  • Purity: 99.4%
  • Physical form: solid (powder)
  • Solubility: DMSO ≥100 mg/mL; in vivo formulations ≥2.5 mg/mL
  • Suggested storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (2 years)
  • Available pack sizes: 5 mg, 10 mg, 25 mg, 50 mg, 100 mg

ENCOMPASS_PREFERRED
5

Medchemexpress LLC 8-benzyl-4-oxo-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid | 960201-81-4 | 99.1% | 329.35 g/mol | C18H19NO5 | 10 MG
SDP

SD-1008 is a small-molecule JAK inhibitor that reduces STAT3-dependent signaling by inhibiting tyrosyl phosphorylation of STAT3, JAK2, and Src. It is supplied as a high-purity research reagent (C18H19NO5, 329.35 g/mol) intended for biochemical and cellular studies of JAK/STAT pathway modulation.

  • Potent JAK/STAT pathway inhibitor.
  • Reported purity 99.1%.
  • Suitable for biochemical and cellular assays.
  • Compact pack sizes for small-scale research use.
  • Molecular formula C18H19NO5 and MW 329.35 g/mol.

ENCOMPASS_PREFERRED
6

Selleck Chemical LLC GA-017-E1145-100MG
SDP

GA-017 inhibits the serine/threonine protein kinases large tumor suppressor kinase 1/2 (LATS1/2) which exerts inhibitory with IC50s against LATS1 and 2 of 4 10 0 79 and 3 92 0 42 nM respectively and competitively inhibits LATS1 and 2 against ATP with Ki (inhibition constant) values of 0 58 0 11 and 0 25 0 03 nM respectively

ENCOMPASS_PREFERRED
7

Selleck Chemical LLC GA-017-E1145-10MM/1ML
SDP

GA-017 inhibits the serine/threonine protein kinases large tumor suppressor kinase 1/2 (LATS1/2) which exerts inhibitory with IC50s against LATS1 and 2 of 4 10 0 79 and 3 92 0 42 nM respectively and competitively inhibits LATS1 and 2 against ATP with Ki (inhibition constant) values of 0 58 0 11 and 0 25 0 03 nM respectively

ENCOMPASS_PREFERRED
8

Selleck Chemical LLC GA-017-E1145-25MG
SDP

GA-017 inhibits the serine/threonine protein kinases large tumor suppressor kinase 1/2 (LATS1/2) which exerts inhibitory with IC50s against LATS1 and 2 of 4 10 0 79 and 3 92 0 42 nM respectively and competitively inhibits LATS1 and 2 against ATP with Ki (inhibition constant) values of 0 58 0 11 and 0 25 0 03 nM respectively

ENCOMPASS_PREFERRED
9

Cayman Chemical SBromoenol lactone
SDP

A selective iPLA2β inhibitor; inhibits vasopressin-induced release of arachidonate from cultured rat aortic smooth muscle (A10) cells (IC50 = 2 µM); >1,000-fold selective for iPLA2 versus cPLA2 and 10-fold selective for iPLA2β versus iPLA2γ

ENCOMPASS_PREFERRED
10

TARGETMOL CHEMICALS INC GAMMA-TOCOTRIENOL 10MG
SDP

Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. (gamma)-Tocotrienol (Plastochromanol) is one of the four types of tocotrienol a type of vitamin E. Itl is also a radioprotector antioxidant. It shows antitumor and antihypertensive effects in vivo. purity: 98%

ENCOMPASS_PREFERRED
11

TARGETMOL CHEMICALS INC TC-G-1008 10MG
SDP

Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. TC-G-1008 (GPR39-C3) is a GPR39 (zinc receptor) agonist (EC50 values are 0.4 and 0.8 nM for rat and human receptors respectively). purity: 99%

ENCOMPASS_PREFERRED
12

Medchemexpress LLC Gamma-mangostin | 31271-07-5 | MFCD00951752 | 99.9% | 396.43 | C23H24O6 | 10 MG
SDP

Gamma-mangostin is a natural xanthone research compound with demonstrated activity as a competitive 5-HT2A receptor antagonist and a potent COX-2 inhibitor. It is used in studies of inflammation, receptor pharmacology, and transthyretin (TTR) stabilization. Supplied as a high-purity solid with recommended DMSO solubility and established in vivo formulation protocols.

  • High purity suitable for biochemical and pharmacology assays.
  • Chemical formula C23H24O6; molecular weight 396.43.
  • Reported activities include 5-HT2A antagonism, COX-2 inhibition, and TTR stabilization.
  • Available in small milligram quantities (including 10 MG) for screening and dose-response studies.
  • Soluble in DMSO with manufacturer-recommended in vivo formulation options.

ENCOMPASS_PREFERRED
13

Medchemexpress LLC Ap-2 gamma/TFAP2C protein, human (His-tag) | >95.0% | 50 UG
SDP

Recombinant human AP-2 gamma (TFAP2C) protein fragment (L128-V223) expressed in E. coli with an N-terminal His tag. Supplied as a sterile lyophilized powder, this high-purity fragment is intended for biochemical assays, antibody validation, and protein-protein interaction studies focusing on the AP-2 gamma DNA-binding domain.

  • Sequence-specific DNA-binding transcription factor fragment.
  • N-terminal 10xHis tag for affinity purification.
  • Purity >95% as determined by reducing SDS-PAGE.
  • Molecular weight approximately 10-14 kDa.
  • Do not reconstitute below 100 μg/mL in ddH2O.
  • Store at -20°C; aliquot and freeze at -20°C or -80°C for long-term.
  • Supplied as sterile lyophilized powder.

ENCOMPASS_PREFERRED
14

TARGETMOL CHEMICALS INC GAMMA-MANGOSTIN 10MG
SDP

Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 1. gamma-Mangostin (Normangostin) as a preventive agent of the metabolic syndrome. 2. Gamma-Mangostin has free radical scavenging activity and antiproliferative and apoptotic activity in HepG2 cells. 3. Gamma-Mangostin could serve as a micronutrient for colon cancer prevention and is a potential lead compound for the development of anti-colon cancer agents. 4. Gamma-Mangostin may acts as an antihypertensive agent by causing vasorelaxation which is mediated via the NO-cGMP pathway. purity: 99%

ENCOMPASS_PREFERRED
15

Medchemexpress LLC Recombinant human AP-2 gamma (TFAP2C) protein, His-tag | >95.0% | 1 MG
SDP

Recombinant human AP-2 gamma (TFAP2C) protein fragment expressed in Escherichia coli and purified via affinity chromatography; provided as a high-purity His-tagged fragment suitable for biochemical characterization and antibody validation.

  • Expressed in E. coli with an N-terminal His tag.
  • Partial sequence L128-V223.
  • Molecular weight approximately 10-14 kDa.
  • Purity >95% as determined by reducing SDS-PAGE.
  • Store at -20°C; freeze aliquots at -20°C or -80°C for extended storage.
  • Suitable for biochemical assays, antibody validation, and protein interaction studies.

ENCOMPASS_PREFERRED