Lactones

alpha-Hydroxy-gamma-butyrolactone 98.0+%, TCI America™

CAS: 19444-84-9 Molecular Formula: C4H6O3 Molecular Weight (g/mol): 102.09 MDL Number: MFCD00134268,MFCD00211245 InChI Key: FWIBCWKHNZBDLS-UHFFFAOYNA-N Synonym: alpha-hydroxy-gamma-butyrolactone,3-hydroxydihydrofuran-2 3h-one,2-hydroxy-gamma-butyrolactone,3-hydroxytetrahydrofuran-2-one,2 3h-furanone, dihydrohydroxy,3s-3-hydroxydihydrofuran-2 3h-one,3-hydroxydihydro-2 3h-furanone,hydroxybutyrolactone,r-dihydro-3-hydroxyfuran-2 3h-one,2 3h-furanone, dihydro-3-hydroxy PubChem CID: 545831 IUPAC Name: 3-hydroxyoxolan-2-one SMILES: OC1CCOC1=O

D-Glucurono-6,3-lactone 99.0+%, TCI America™

CAS: 32449-92-6 Molecular Formula: C6H8O6 Molecular Weight (g/mol): 176.124 MDL Number: MFCD00135622 InChI Key: UYUXSRADSPPKRZ-KKQCNMDGSA-N Synonym: d-glucuro-3,6-lactone PubChem CID: 91634076 IUPAC Name: (2S)-2-[(2S,3S,4R)-3,4-dihydroxy-5-oxooxolan-2-yl]-2-hydroxyacetaldehyde SMILES: C(=O)C(C1C(C(C(=O)O1)O)O)O

D(+)-Glucurono-3,6-lactone, 99+%

CAS: 32449-92-6 MDL Number: MFCD00135622 InChI Key: UYUXSRADSPPKRZ-KKQCNMDGSA-N Synonym: d-glucuro-3,6-lactone PubChem CID: 91634076 IUPAC Name: (2S)-2-[(2S,3S,4R)-3,4-dihydroxy-5-oxooxolan-2-yl]-2-hydroxyacetaldehyde SMILES: C(=O)C(C1C(C(C(=O)O1)O)O)O

Pilocarpine hydrochloride, 99.3%, MP Biomedicals™

CAS: 54-71-7 Molecular Formula: C11H17ClN2O2 Molecular Weight (g/mol): 244.72 MDL Number: MFCD00012722 InChI Key: RNAICSBVACLLGM-GNAZCLTHSA-N Synonym: pilocarpine hydrochloride,+-pilocarpine hydrochloride,pilocarpal,pilocar,pilocar smp,almocarpine,pilomiotin,pilovisc,pilocel,pilocarpine hcl PubChem CID: 5909 IUPAC Name: hydrogen (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]oxolan-2-one chloride SMILES: [H+].[Cl-].CC[C@H]1[C@@H](CC2=CN=CN2C)COC1=O

Mevastatin, 98%

CAS: 73573-88-3 Molecular Formula: C23H34O5 Molecular Weight (g/mol): 390.52 MDL Number: MFCD05662341 InChI Key: AJLFOPYRIVGYMJ-INTXDZFKSA-N Synonym: mevastatin,compactin,mevastatinum,mevastatina,mevastatine,mevastatinum inn-latin,antibiotic ml 236b,mevastatin inn,compactin penicillium,mevastatine inn-french PubChem CID: 64715 ChEBI: CHEBI:34848 IUPAC Name: [(1S,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate SMILES: CC[C@H](C)C(=O)O[C@H]1CCC=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12

L(+)-Gulonic acid gamma-lactone, 95+%

CAS: 1128-23-0 Molecular Formula: C₆H₁₀O₆ Molecular Weight (g/mol): 178.14 InChI Key: SXZYCXMUPBBULW-SKNVOMKLSA-N Synonym: l-gulonolactone,l-gulono-1,4-lactone,l-gulonic acid gamma-lactone,3s,4r,5r-5-s-1,2-dihydroxyethyl-3,4-dihydroxydihydrofuran-2 3h-one,l-gulono-gamma-lactone,gamma-gulonolactone,l-gulonic gamma-lactone,l-+-gulono-1,4-lactone,l +-gulonic acid gamma-lactone,l-+-gulonic acid gamma-lactone PubChem CID: 439373 ChEBI: CHEBI:17587 IUPAC Name: (3S,4R,5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-one SMILES: C(C(C1C(C(C(=O)O1)O)O)O)O

DL-Pantolactone, 97%

CAS: 79-50-5 Molecular Formula: C₆H₁₀O₃ Molecular Weight (g/mol): 130.14 MDL Number: MFCD00064333 InChI Key: SERHXTVXHNVDKA-UHFFFAOYSA-N Synonym: pantolactone,dl-pantolactone,3-hydroxy-4,4-dimethyldihydrofuran-2 3h-one,pantoyl lactone,pantoic lactone,dl-pantoyl lactone,d---pantolactone,2 3h-furanone, dihydro-3-hydroxy-4,4-dimethyl,dihydro-3-hydroxy-4,4-dimethyl-2 3h-furanone,pantolyl lactone PubChem CID: 989 IUPAC Name: 3-hydroxy-4,4-dimethyloxolan-2-one SMILES: CC1(COC(=O)C1O)C

3-Chloro-2,4(3H,5H)-furandione, 97%

CAS: 4971-55-5 Molecular Formula: C4H3ClO3 Molecular Weight (g/mol): 134.52 MDL Number: MFCD00134273 InChI Key: DJEJYZZJYYNADA-UHFFFAOYNA-N Synonym: 3-chloro-2,4 3h,5h-furandione,3-chlorofuran-2,4 3h,5h-dione,3-chloro-furan-2,4-dione,3-chlorotetronic acid,2,4 3h,5h-furandione, 3-chloro,3-chloro-3,5-dihydrofuran-2,4-dione,acmc-209khp,3-chlorofuran-2,4-dione,3-chloranyloxolane-2,4-dione,3-chlorotetrahydrofuran-2,4-dione PubChem CID: 4158575 IUPAC Name: 3-chlorooxolane-2,4-dione SMILES: ClC1C(=O)COC1=O

(-)-Camphanic acid chloride, 98%

CAS: 39637-74-6 Molecular Formula: C₁₀H₁₃ClO₃ Molecular Weight (g/mol): 216.66 MDL Number: MFCD00135626 InChI Key: PAXWODJTHKJQDZ-QVDQXJPCSA-N Synonym: 1s-4,7,7-trimethyl-3-oxo-2-oxabicyclo 2.2.1 heptane-1-carbonyl chloride,--1s,4r-camphanoyl chloride,1s---camphanic acid chloride PubChem CID: 12364938 IUPAC Name: (4S)-1,7,7-trimethyl-2-oxo-3-oxabicyclo[2.2.1]heptane-4-carbonyl chloride SMILES: CC1(C2(CCC1(OC2=O)C(=O)Cl)C)C

D(-)-Pantolactone, 99%

CAS: 599-04-2 Molecular Formula: C₆H₁₀O₃ Molecular Weight (g/mol): 130.14 MDL Number: MFCD00005392 InChI Key: SERHXTVXHNVDKA-BYPYZUCNSA-N Synonym: d---pantolactone,r-pantolactone,d-pantolactone,r-pantoyl lactone,d---pantoyl lactone,pantothenic lactone,r-3-hydroxy-4,4-dimethyldihydrofuran-2 3h-one,unii-j288d7o0js,2 3h-furanone, dihydro-3-hydroxy-4,4-dimethyl-, 3r,r---pantolactone PubChem CID: 439368 ChEBI: CHEBI:16719 IUPAC Name: (3R)-3-hydroxy-4,4-dimethyloxolan-2-one SMILES: CC1(COC(=O)C1O)C

Gibberellic acid, 98%

CAS: 77-06-5 Molecular Formula: C19H22O6 Molecular Weight (g/mol): 346.38 MDL Number: MFCD00079329 InChI Key: IXORZMNAPKEEDV-QTWFBFKQSA-N Synonym: gibberellic acid,gibberellin a3,gibberellin,gibreskol,brellin,cekugib,grocel,gibberellin x,gibberellic acid ga3,gib-tabs PubChem CID: 91757643 IUPAC Name: (1R,2R,5S,8S,9S,10R,12S)-5,12-dihydroxy-11-methyl-6-methylidene-16-oxo-15-oxapentacyclo[9.3.2.1⁵,⁸.0¹,¹⁰.0²,⁸]heptadec-13-ene-9-carboxylic acid SMILES: CC12[C@H]3[C@H](C(O)=O)[C@@]45CC(=C)[C@@](O)(C4)CC[C@H]5[C@]3(OC1=O)C=C[C@@H]2O

Medchemexpress LLC AMPK gamma 1/beta 2/alpha 2 heterotrimer protein | >90.0% | 10 UG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

Recombinant human AMPK gamma 1/beta 2/alpha 2 heterotrimer protein produced in Sf9 insect cells with N-terminal His and GST tags. Supplied as a 0.22 μm filtered solution in Tris-NaCl buffer with stabilizers, the protein shows high purity and measurable kinase activity suitable for biochemical assays and structural studies. Store frozen and avoid repeated freeze-thaw cycles.

• Recombinant heterotrimeric AMPK composed of gamma 1, beta 2, and alpha 2 subunits.
• Expressed in Sf9 insect cells for eukaryotic folding and post-translational processing.
• N-terminal His and GST tags for affinity purification and detection.
• Purity greater than 90% as determined by reducing SDS-PAGE.
• Supplied in a stabilized buffer formulation containing Tris, NaCl, EDTA, DTT, glycerol, and antioxidants.
• Specific activity of 1-6 nmol/min/mg measured using SAMS peptide.
• Available in small aliquots to minimize freeze-thaw and preserve activity.

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Medchemexpress LLC AMPK gamma 1/beta 2/alpha 1 heterotrimer protein, human | 96.3% | 10 UG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

Recombinant human AMPK α1β2γ1 heterotrimer protein expressed in Sf9 insect cells with an N-terminal His-GST tag. Supplied as a purified recombinant complex for in vitro kinase assays, biochemical characterization, and screening of modulators that affect AMPK activity.

• Expressed in Sf9 insect cells with an N-terminal His-GST tag.
• Purity approximately 96.3%.
• Subunit molecular weights approx. 95 kDa (α1), 37 kDa (β2), 35 kDa (γ1).
• Validated for in vitro kinase assays and biochemical profiling.
• Supplied in microgram quantities suitable for biochemical assays.

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Medchemexpress LLC TC-G-1008 | 1621175-65-2 | 99.4% | 418.90 | C18H19ClN6O2S | 10 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

TC-G-1008 (GPR39-C3) is a small-molecule, orally available agonist of the G protein-coupled receptor GPR39, supplied as a high-purity solid for in vitro and in vivo pharmacology. It exhibits sub-nanomolar potency (EC50 0.4 nM in rat, 0.8 nM in human) and is suitable for receptor pharmacology, target validation, and pharmacodynamic studies.

• Molecular formula: C18H19ClN6O2S
• Molecular weight: 418.90
• Purity: 99.4%
• Physical form: solid (powder)
• Solubility: DMSO ≥100 mg/mL; in vivo formulations ≥2.5 mg/mL
• Suggested storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (2 years)
• Available pack sizes: 5 mg, 10 mg, 25 mg, 50 mg, 100 mg

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

eMolecules​ 344884-10-2 | TERT-BUTYL 2-(HYDROXYMETHYL)-5-OXOPYRROLIDINE-1-CARBOXYLATE | AstaTech | MFCD24532043 | 215.249 | C10H17NO4 | 95.000 | CC(C)(C)OC(=O)N1C(CO)CCC1=O | 0.25g | 386413500

TERT-BUTYL 2-(HYDROXYMETHYL)-5-OXOPYRROLIDINE-1-CARBOXYLATE | AstaTech | 344884-10-2 | MFCD24532043 | 215.249 | C10H17NO4 | 95.000 | CC(C)(C)OC(=O)N1C(CO)CCC1=O | 0.25g | 386413500

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More