Oxazinanes
Apexbio Technology LLC THIP hydrochloride 85118-33-8 10mM (in 1mL DMSO)
THIP hydrochloride (CAS 85118-33-8) is a small-molecule agonist of GABA receptors with primary activity in the central nervous system It selectively binds to GABAA receptor subtypes displaying affinity for 1 2 2 5 and 4 3 subunits In pharmacological studies THIP hydrochloride demonstrates subunit-specific efficacy with ED50 values of 143 M for 1 2 2 28 129 M for 5 and 6 M for 4 3 This compound is widely employed as a research tool in neuroscience to investigate GABAergic neurotransmission receptor pharmacology and explore potential therapeutic strategies related to neural modulation
TARGETMOL CHEMICALS INC ALE-0540 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ALE-0540 is a nonpeptidic heterocyclic molecule that inhibits the binding of NGF to p75 and TrkA as well as signal transduction and biological responses mediated by TrkA receptors. purity: 97%
Medchemexpress LLC Sapropterin dihydrochloride | 69056-38-8 | 99.8% | C9H17Cl2N5O3 | 50 MG
Sapropterin ((6R)-BH4; (6R)-Tetrahydro-L-biopterin) dihydrochloride is an orally active phenylalanine hydroxylase (PAH) cofactor. It is effective in reducing blood phenylalanine concentrations and can be used in the study of phenylketonuria (PKU). Additionally, Sapropterin dihydrochloride can aggravate experimental autoimmune encephalomyelitis (EAE).
- Orally active phenylalanine hydroxylase (PAH) cofactor.
- Effective in reducing blood phenylalanine concentrations.
- Used in the study of phenylketonuria (PKU).
- Can aggravate experimental autoimmune encephalomyelitis (EAE).
eMolecules 198959-37-4 | Methyl pyrrolidine-3-carboxylate hydrochloride | ChemScene | MFCD08436169 | 165.620 | C6H12ClNO2 | 95.000 | Cl.COC(=O)C1CCNC1 | 5g | 572228223
Methyl pyrrolidine-3-carboxylate hydrochloride | ChemScene | 198959-37-4 | MFCD08436169 | 165.620 | C6H12ClNO2 | 95.000 | Cl.COC(=O)C1CCNC1 | 5g | 572228223
TARGETMOL CHEMICALS INC Sonlicromanol hydrochloride
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Sonlicromanol hydrochloride (KH176 hydrochloride) is a ROS-redox modulator that crosses the blood-brain barrier, has potential anticancer activity, improves m.3243A>G heterogeneity in iPSC-derived neurons associated with It has potential anticancer activity, ameliorates neuronal network dysfunction and transcriptomic changes associated with m.3243A>G heterogeneity in iPSC-derived neurons, and can be used for the treatment of mitochondrial diseases. Purity 99.53%
TARGETMOL CHEMICALS INC PNU-177864 HYDROCHLORIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. PNU-177864 hydrochloride is a potent selective and orally active antagonist of dopamine D3 receptor. PNU-177864 hydrochloride is structurally consistent with a cationic amphiphilic drug (CAD). PNU-177864 hydrochloride induces phospholipidosis in vivo. PNU-177864 hydrochloride exhibits antischizophrenic activity. purity: 99%
Cayman Chemical SH1152 hydrochloride
A potent, specific, ATP-competitive, and cell permeable inhibitor of ROCK (Ki = 1.6 nM); more potent inhibitor of ROCK than either Y-27632 (Ki = 140 nM) or HA-1077 (Ki = 330 nM); poorly inhibits PKA, PKC, and MLCK
TARGETMOL CHEMICALS INC GSK778 HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GSK778 hydrochloride hydrochloride is a potent and selective BD1 bromodomain inhibitor of the BET proteins with IC50s of 75 nM (BRD2 BD1) 41 nM (BRD3 BD1) 41 nM (BRD4 BD1) and 143 nM (BRDT BD1) respectively. GSK778 hydrochloride hydrochloride phenocopies the effects of pan-BET inhibitors in cancer models[1]. purity: 98%
![eMolecules 1818843-14-9 | TERT-BUTYL N-[(2R)-AZETIDIN-2-YLMETHYL]CARBAMATE HCL | AstaTech | MFCD28893974 | 222.710 | C9H19ClN2O2 | 95.000 | Cl.CC(C)(C)OC(=O)NC[C@H]1CCN1 | 1g | 449781062](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502697439.jpg-250.jpg)
eMolecules 1818843-14-9 | TERT-BUTYL N-[(2R)-AZETIDIN-2-YLMETHYL]CARBAMATE HCL | AstaTech | MFCD28893974 | 222.710 | C9H19ClN2O2 | 95.000 | Cl.CC(C)(C)OC(=O)NC[C@H]1CCN1 | 1g | 449781062
TERT-BUTYL N-[(2R)-AZETIDIN-2-YLMETHYL]CARBAMATE HCL | AstaTech | 1818843-14-9 | MFCD28893974 | 222.710 | C9H19ClN2O2 | 95.000 | Cl.CC(C)(C)OC(=O)NC[C@H]1CCN1 | 1g | 449781062
Selleck Chemical LLC Eperisone hydrochloride S4877-25mg
Eperisone hydrochloride is muscle relaxant agent with antispasmodic effects It is widely used in the treatment of patients with muscular contractures low back pain or spasticity
Medchemexpress LLC Tebanicline (dihydrochloride) | 209326-19-2 | MFCD01758464 | 99.5% | 271.57 g/mol | C9H13Cl3N2O | 5 MG
Tebanicline dihydrochloride is the dihydrochloride salt of tebanicline (ABT-594), a potent nicotinic acetylcholine receptor (nAChR) ligand used in research on analgesia and receptor pharmacology. The compound is supplied as a solid research-use reagent (CAS 209326-19-2) with molecular formula C9H13Cl3N2O and molecular weight 271.57 g/mol.
Selleck Chemical LLC Bobcat339 hydrochloride
Bobcat339 is a selective cytosine-based TET enzyme inhibitor with IC50 of 33 M and 73 M for TET1 and TET2 respectively Bobcat339 can reduce DNA 5-hydroxymethylcytosine abundance by inhibiting TET enzyme function in living cells and provide support for its utility as a viable pharmacological probe
Medchemexpress LLC Pirenzepine dihydrochloride | 29868-97-1 | 99.8% | 424.32 | 1 G
Pirenzepine dihydrochloride is a selective M1 muscarinic acetylcholine receptor antagonist that poorly penetrates the blood-brain barrier. It is used in peptic ulcer research due to its ability to reduce gastric acid secretion and muscle spasm. This compound also exhibits anti-proliferative activity against cancer cells.
- Selective M1 muscarinic acetylcholine receptor antagonist.
- Reduces gastric acid secretion.
- Reduces muscle spasm.
- Useful in peptic ulcer research.
- Exhibits anti-proliferative activity against cancer cells.
Medchemexpress LLC Quizartinib dihydrochloride | 1132827-21-4 | 99.8% | C29H34Cl2N6O4S | 50 MG
Quizartinib dihydrochloride is an orally active, highly selective, and potent second-generation type II FLT3 tyrosine kinase inhibitor. It inhibits wild-type FLT3 and FLT3-ITD autophosphorylation in MV4-11 cells and can induce apoptosis.
- Orally active FLT3 tyrosine kinase inhibitor
- Highly selective and potent
- Inhibits FLT3 and FLT3-ITD autophosphorylation
- Can be linked to VHL ligand for PROTAC FLT3 degrader formation
- Induces apoptosis
Selleck Chemical LLC Tribenzagan Hydrochloride
Tribenzagan Hydrochloride (Trimethobenzamide) is an orally available antiemetic agent used in the therapy of nausea and vomiting associated with medications and gastrointestinal viral and other illnesses