Oxazinanes
Medchemexpress LLC Pramipexole dihydrochloride hydrate | 191217-81-9 | 98.0% | 5 MG
Pramipexole dihydrochloride hydrate | 191217-81-9 | 98.0% | 5 MG
c1ccccc1 | 1g | 525307271](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000493374.jpg-250.jpg)
eMolecules 1225376-02-2 | (R)-2-Phenylmorpholine | J & W PharmLab LLC | MFCD18249849 | 163.220 | C10H13NO | 96.000 | C1CO[C@@H](CN1)c1ccccc1 | 1g | 525307271
(R)-2-Phenylmorpholine | J & W PharmLab LLC | 1225376-02-2 | MFCD18249849 | 163.220 | C10H13NO | 96.000 | C1CO[C@@H](CN1)c1ccccc1 | 1g | 525307271
eMolecules 16681-67-7 | 4-Bromo-2-methyl-2H-[1,2,3]triazole | J&W PharmLab LLC | MFCD23378485 | 161.990 | C3H4BrN3 | 96.000 | Cn1ncc(Br)n1 | 1g | 773120107
4-Bromo-2-methyl-2H-[1,2,3]triazole | J&W PharmLab LLC | 16681-67-7 | MFCD23378485 | 161.990 | C3H4BrN3 | 96.000 | Cn1ncc(Br)n1 | 1g | 773120107
![eMolecules 16681-67-7 | 4-Bromo-2-methyl-2H-[1,2,3]triazole | J&W PharmLab LLC | MFCD23378485 | 161.990 | C3H4BrN3 | 96.000 | Cn1ncc(Br)n1 | 5g | 773120108](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000474146.jpg-250.jpg)
eMolecules 16681-67-7 | 4-Bromo-2-methyl-2H-[1,2,3]triazole | J&W PharmLab LLC | MFCD23378485 | 161.990 | C3H4BrN3 | 96.000 | Cn1ncc(Br)n1 | 5g | 773120108
4-Bromo-2-methyl-2H-[1,2,3]triazole | J&W PharmLab LLC | 16681-67-7 | MFCD23378485 | 161.990 | C3H4BrN3 | 96.000 | Cn1ncc(Br)n1 | 5g | 773120108
Medchemexpress LLC Tebanicline dihydrochloride | 209326-19-2 | 99.5% | C9H13Cl3N2O | 50 MG
Tebanicline dihydrochloride is a nAChR modulator with potent, orally effective analgesic activity. It inhibits the binding of cytisine to α4β2 neuronal nAChRs with a Ki of 37 pM.
- nAChR modulator
- Potent and orally effective analgesic activity
- Inhibits binding of cytisine to α4β2 neuronal nAChRs with a Ki of 37 pM
- Potent antinociceptive agent with full efficacy in models of acute and persistent pain
- Produces significant antinociceptive effects in mice against acute noxious thermal stimulation
- Orally active
- Has antinociceptive effects in rat models of acute thermal, persistent chemical, and neuropathic pain
Medchemexpress LLC Quizartinib dihydrochloride | 1132827-21-4 | 99.8% | C29H34Cl2N6O4S | 50 MG
Quizartinib dihydrochloride is an orally active, highly selective, and potent second-generation type II FLT3 tyrosine kinase inhibitor. It inhibits wild-type FLT3 and FLT3-ITD autophosphorylation in MV4-11 cells and can induce apoptosis.
- Orally active FLT3 tyrosine kinase inhibitor
- Highly selective and potent
- Inhibits FLT3 and FLT3-ITD autophosphorylation
- Can be linked to VHL ligand for PROTAC FLT3 degrader formation
- Induces apoptosis
Medchemexpress LLC 13,14-Dihydro-15-keto-PGE2-d9 | 2750534-81-5 | 361.52 | 25 UG
13,14-Dihydro-15-keto-PGE2-d9 is the deuterium labeled 13,14-Dihydro-15-keto-PGE2. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled compound
- Incorporates stable heavy isotopes of hydrogen, carbon, and other elements
- Affects pharmacokinetic and metabolic profiles of drugs
- For research use only
Medchemexpress LLC Cetylpyridinium chloride monohydrate | 6004-24-6 | 99.8% | 1 ML
Cetylpyridinium chloride monohydrate is a cationic quaternary ammonium compound that functions as an antiseptic, effectively killing bacteria and other microorganisms. It is commonly used in various oral hygiene products to prevent plaque and reduce gingivitis. This compound also exhibits biological activity against viruses and in cellular models, and has been studied in clinical trials for conditions such as SARS-CoV-2 infection and periodontal diseases.
- Cationic quaternary ammonium compound
- Functions as an antiseptic
- Kills bacteria and other microorganisms
- Prevents plaque and reduces gingivitis
- Used in mouthwashes, toothpastes, and throat/nasal sprays
- Disrupts influenza viral envelope
- Exhibits dose-dependent cytotoxicity in MDCK cells
- Enhances survival and reduces influenza-associated morbidity and mortality in mice
Apexbio Technology LLC BARNIDIPINE-HYDROCHLORIDE
Barnidipine (hydrochloride) (CAS No 104757-53-1) is a calcium channel blocker used predominantly in cardiovascular research Originating from the dihydropyridine class of compounds it operates by inhibiting L-type calcium channels thereby reducing calcium influx into vascular smooth muscle cells and cardiac myocytes Its mechanism of action results in vasodilation and decreased vascular resistance contributing to its antihypertensive effects In vitro Barnidipine exhibits activity in the nanomolar to low micromolar range It is commonly applied in cell models such as vascular smooth muscle cells and cardiomyocytes as well as in animal studies to evaluate cardiovascular effects Barnidipine is also utilized in drug screening processes to assess potential therapeutic benefits and pharmacological properties Experimental concentrations typically depend on the specific research design
Apexbio Technology LLC LEE011-HYDROCHLORIDE-2MG
LEE011 hydrochloride (CAS No 1211443-80-9) is a potent cyclin-dependent kinase 4/6 (CDK4/6) inhibitor primarily utilized in oncology research It originates from the need to halt the progression of cancer cells by disrupting the cell cycle targeting the CDK4/6-Rb pathway In vitro LEE011 hydrochloride demonstrates efficacy in the nanomolar to low micromolar range effectively inhibiting cell proliferation across various cancer cell lines It is frequently employed in cell models and animal studies to evaluate its therapeutic potential and synergy with other anticancer agents Additionally this compound is widely used in drug screening and preclinical trials to assess its viability as a treatment option Experimental concentrations typically depend on the specific research design ensuring its application is tailored to the desired outcomes in scientific investigations
Apexbio Technology LLC PROPACETAMOL-HYDROCHLORIDE
Propacetamol hydrochloride (CAS No 66532-86-3) is a prodrug of paracetamol commonly used in biomedical research for its analgesic and antipyretic properties It originates from the enzymatic conversion process where it rapidly hydrolyzes to release paracetamol which then exerts its effects by inhibiting cyclooxygenase enzymes and reducing the synthesis of prostaglandins in the central nervous system In vitro studies often show activity in the nanomolar to low micromolar range indicating its potent efficacy Typically it is used in cell models and animal studies to investigate pain management mechanisms and in drug screening strategies for analgesic development Experimental concentrations typically depend on the specific research design