Oxazinanes
Selleck Chemical LLC Kevetrin hydrochloride
Kevetrin hydrochloride (Thioureidobutyronitrile) is a water-soluble small molecule and activator of the tumor suppressor protein p53 with potential antineoplastic activity
eMolecules 7778-42-9 | Sulfamoyl chloride | Oakwood Chemical | MFCD11519990 | 115.530 | ClH2NO2S | 95.000 | NS(Cl)(=O)=O | 250mg | 806975989
Sulfamoyl chloride | Oakwood Chemical | 7778-42-9 | MFCD11519990 | 115.530 | ClH2NO2S | 95.000 | NS(Cl)(=O)=O | 250mg | 806975989
eMolecules 121492-06-6 | N-Boc-N-methylethylenediamine | Ambeed | MFCD01317789 | 174.244 | C8H18N2O2 | 98.000 | CN(CCN)C(=O)OC(C)(C)C | 25g | 552722211
N-Boc-N-methylethylenediamine | Ambeed | 121492-06-6 | MFCD01317789 | 174.244 | C8H18N2O2 | 98.000 | CN(CCN)C(=O)OC(C)(C)C | 25g | 552722211
Selleck Chemical LLC (S.R.S)-AHPC hydrochloride S1062-1g
(S R S)-AHPC hydrochloride (VH032-NH2 VHL ligand 1) is the VH032-based VHL ligand that is applicable to the recruitment of the von Hippel-Lindau (VHL) protein (S R S)-AHPC hydrochloride can be connected to the ligand for protein by a linker to form PROTACs
Medchemexpress LLC Ipatasertib dihydrochloride | 1396257-94-5 | C24H34Cl3N5O2 | 200 MG
Ipatasertib dihydrochloride is a highly selective and ATP-competitive pan-Akt inhibitor, with IC50s of 5, 18, and 8 nM for Akt1, Akt2, and Akt3 respectively. It demonstrates potent efficacy in xenograft models where Akt is activated due to genetic alterations, leading to tumor growth delay, stasis, or regression. This compound is intended for research use only.
- Highly selective and ATP-competitive pan-Akt inhibitor.
- IC50s of 5, 18, and 8 nM for Akt1, Akt2, and Akt3.
- Significant selectivity for Akt1 compared to closely related kinases.
- Effective in xenograft models with Akt activation due to genetic alterations.
- Induces tumor growth delay, stasis, or regression in vivo.
- Enhances tumor regression and stasis when used in combination therapies.
- Increases tumor growth inhibition in ovarian cancer models when combined with other agents.
eMolecules 81893-75-6 | 4-(Methylamino)butanoic acid ethyl ester HCl | Acrotein ChemBio Inc. | MFCD17215565 | 181.660 | C7H16ClNO2 | 97.000 | Cl.CCOC(=O)CCCNC | 1g | 705837559
4-(Methylamino)butanoic acid ethyl ester HCl | Acrotein ChemBio Inc. | 81893-75-6 | MFCD17215565 | 181.660 | C7H16ClNO2 | 97.000 | Cl.CCOC(=O)CCCNC | 1g | 705837559
Selleck Chemical LLC Dasatinib hydrochloride S5254-1g
Dasatinib hydrochloride (BMS-354825) is the hydrochloride salt form of dasatinib an inhibitor that targets Abl Src and c-Kit with IC50 of 1 nM 0 8 nM and 79 nM in cell-free assays respectively
Selleck Chemical LLC Isoxsuprine hydrochloride
Isoxsuprine hydrochloride is a beta-adrenergic agonist with vasodilator activity
Biomatik Corporation BCIP, Toluidine Salt (BCIP-T). Grade Ultra Pure. Storage -20C. CAS 6578-06-9
BCIP, Toluidine Salt (BCIP-T). Grade Ultra Pure. Storage -20C. CAS 6578-06-9
eMolecules 16681-67-7 | 4-Bromo-2-methyl-2H-1,2,3-triazole | Ambeed | MFCD23378485 | 161.990 | C3H4BrN3 | 95.000 | Cn1ncc(Br)n1 | 5g | 525043186
4-Bromo-2-methyl-2H-1,2,3-triazole | Ambeed | 16681-67-7 | MFCD23378485 | 161.990 | C3H4BrN3 | 95.000 | Cn1ncc(Br)n1 | 5g | 525043186
TARGETMOL CHEMICALS INC PFI-2 HYDROCHLORIDE 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. PFI-2 hydrochloride ((R)-PFI-2 hydrochloride) is a potent highly selective and cell-active inhibitor of the methyltransferase activity of SETD7 (IC50 2 nM) 500 fold active than (S)-PFI-2. purity: 99%
TARGETMOL CHEMICALS INC EPZ020411 HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. EPZ020411 hydrochloride is a selective and potent small molecule PRMT6 inhibitor with an IC50 value of 10 nM. purity: 100%
Apexbio Technology LLC Memantine hydrochloride 41100-52-1 10mM (in 1mL DMSO)
Memantine hydrochloride (CAS 41100-52-1) is a selective noncompetitive NMDA receptor antagonist Biochemically memantine preferentially inhibits recombinant rat NMDA receptors expressed as NR1a/NR2A NR1a/NR2B and NR1a/NR2D subunits with reported IC50 values of 0 93 M 0 82 M and 0 47 M respectively Studies using HEK293 cells transiently expressing these receptor subunits indicate that this inhibition is voltage- and dose-dependent exhibiting rapid channel unblocking kinetics Clinically memantine is used for Alzheimer s disease Parkinson s disease and spasticity it is additionally investigated in vitro for reducing amyloid-beta toxicity and tau phosphorylation
Medchemexpress LLC NNC 38-1049 | 757183-18-9 | 99.8% | 250 MG
NNC 38-1049 is a research compound that functions as a potent, orally active, competitive histamine H3 receptor antagonist with reported activity in central histaminergic pathways and effects on feeding behavior.
- Orally active, potent, competitive histamine H3 receptor antagonist.
- Increases extracellular histamine levels in the paraventricular nucleus.
- Shown to decrease food intake and body weight in preclinical studies.
- Reported purity 99.84%.
- Chemical formula C19H25ClN2O2; molecular weight 348.87 g·mol⁻¹.
Selleck Chemical LLC Cariprazine hydrochloride
Cariprazine hydrochloride(RGH188 hydrochloride) is a novel antipsychotic agent and is a highly selective partial agonist of dopamineD2 and D3 and 5HT1A receptors with preferential binding to the D3 receptor It exhibits high selectivity and affinity to dopamine D3 (Ki 0 085 nM) and D2 (Ki 0 49 nM) receptors and has moderate affinity for the 5-HT1A receptor (Ki 2 6 nM)