Oxazinanes
Selleck Chemical LLC Colesevelam Hydrochloride
Colesevelam Hydrochloride is an orally administered non-absorbable polymeric bile-acid-binding agent with a higher affinity for glycocholic acid in vitro
Selleck Chemical LLC Vazegepant hydrochloride
Vazegepant hydrochloride (BHV-3500 Zavegepant) is a highly potent selective and structurally unique small molecule antagonist of CGRP receptor It can also be used for the acute treatment of migraine
Aobchem (2 6-Difluorophenyl)(morpholino)methanone | 95% | CAS 717858-98-5 | C11H11F2NO2 | 1g
(2 6-Difluorophenyl)(morpholino)methanone | 95% | CAS 717858-98-5 | C11H11F2NO2 | 1g
Aobchem (2 6-Difluorophenyl)(morpholino)methanone | 95% | CAS 717858-98-5 | C11H11F2NO2 | 5g
(2 6-Difluorophenyl)(morpholino)methanone | 95% | CAS 717858-98-5 | C11H11F2NO2 | 5g
Aobchem -Bromo-2-chloro-4-((morpholin-4-yl)methyl)benzene | 97% | CAS 952289-86-0 | C11H13BrClNO | 500mg
-Bromo-2-chloro-4-((morpholin-4-yl)methyl)benzene | 97% | CAS 952289-86-0 | C11H13BrClNO | 500mg
AdipoGen Verapamil hydrochloride
Chemical. CAS 152-11-4. Formula C27H38N2O4 . HCl. MW 491.06. Synthetic Verapamil hydrochloride is an alpha-adrenergic receptor alpha-AR antagonist and calcium channel protein inhibitor that blocks the L-type Ca2 channels in smooth and cardiac muscle cells. Verapamil is an antiarrhythmic agent and vasodilator known to reduce the renal clearance of digoxin and induce apoptosis in primary and metastatic colon adenocarcinoma human cell lines in vitro. It has been observed that verapamil can induce currents by itself, presumably by acting on the potassium and chloride leakage. Verapamil has also been used as an inhibitor of drug efflux pump proteins such as Mdr P-glycoprotein. Verapamil is a substrate of CYP3A4 and CYP2C6. It is also used in fluorescent cell sorting for DNA content, as it blocks efflux of a variety of DNA-binding fluorophores such as Hoechst 33342. Recent research has shown verapamil to be an effective treatment for diabetes in animal models.
Aobchem (5-Butyl-2-ethoxyphenyl)boronic acid | 95% | C12H19BO3 | 1g
(5-Butyl-2-ethoxyphenyl)boronic acid | 95% | C12H19BO3 | 1g
Aobchem 1-(1 2-Dihydro-5-acenaphthylenyl)cyclobutanol | 95% | CAS 2250110-79-1 | C16H16O | 1g
1-(1 2-Dihydro-5-acenaphthylenyl)cyclobutanol | 95% | CAS 2250110-79-1 | C16H16O | 1g
Sigma Aldrich Fine Chemicals Biosciences TrizmaR hydrochloride solu
Tris hydrochloride is used to prepare buffer mainly at a physiological range of 7.3 to 7.5. This buffer is well-suited with biological fluids. It is used in laboratories as primary pH standard in clinical laboratories.
Sigma Aldrich Fine Chemicals Biosciences TrizmaR hydrochloride solu
A series of Pre-mixed SOLUTIONons of TRIZMA Base and TRIZMA HCl to provide commonly used pH values for Tris buffers. No mixing or pH adjustment necessary. Guaranteed accuracy /- 0.1 pH units.
Sigma Aldrich Fine Chemicals Biosciences TrizmaR hydrochloride solu
A series of Pre-mixed SOLUTIONons of TRIZMA Base and TRIZMA HCl to provide commonly used pH values for Tris buffers. No mixing or pH adjustment necessary. Guaranteed accuracy /- 0.1 pH units.
Medchemexpress LLC Iadademstat (dihydrochloride) | 1431303-72-8 | 99.98% | 1 ML
Product Overview
Iadademstat (ORY-1001) is a highly potent, orally active, and selective LSD1 (KDM1A) inhibitor that exhibits antileukemic activity. It is intended for research use, particularly in studies concerning relapsed or refractory acute myeloid leukemia.Features and Benefits
- Highly potent, orally active, and selective LSD1 (KDM1A) inhibitor.
- Exhibits antileukemic activity.
- Can be used for research on relapsed or refractory acute myeloid leukemia.
- Inhibits the proliferation of cancer cells (H1299 and A549), arrests the cell cycle at G1 phase, and induces apoptosis in vitro.
- Decreases glycolysis in H1299 and A549 cells by reducing HK2 protein levels in vitro.
- Demonstrates antitumor activity and increases survival rate in glioblastoma xenograft mouse models in vivo.
Medchemexpress LLC Aebsf (hydrochloride) | 30827-99-7 | 99.87% | 10 MM 1 ML
AEBSF hydrochloride is an irreversible inhibitor of serine proteases such as chymotrypsin, kallikrein, plasmin, thrombin, and trypsin. It inhibits Aβ production by directly inhibiting β-secretase in various human cell lines and suppresses lysis of leukemic cells by human macrophages. It also interferes with blastocyst growth and HeLa cell adhesion. In vivo, AEBSF prolongs survival in *T. gondii* infection models and reduces inflammation in murine models.
- Irreversible inhibitor of serine proteases (chymotrypsin, kallikrein, plasmin, thrombin, and trypsin).
- Inhibits β-secretase and macrophage-mediated leukemic cell lysis.
- Disturbs blastocyst growth and cell adhesion.
- Supports research on *T. gondii* infection and inflammation.
- Appearance: Solid, white to off-white.