Oxazinanes
Medchemexpress LLC 7,8-Dihydro-L-biopterin | 6779-87-9 | 99.79% | 239.23 | 100 MG
7,8-Dihydro-L-biopterin is a NOS uncoupling inducer that can cross the blood-brain barrier. It is a reduced non-conjugated pteridine and the main metabolite of 4-amino-tetrahydro-L-biopterin, which undergoes photooxidation to form biopterin. This compound promotes the conversion of nitric oxide synthase to a superoxide-producing form, leading to increased oxidative stress in the renal outer medulla and inducing apoptosis.
- NOS uncoupling inducer
- Can cross the blood-brain barrier
- Promotes conversion of nitric oxide synthase to a superoxide-producing form
- Increases oxidative stress in the renal outer medulla
- Induces apoptosis
- Sensitive to inhibitory effect of SOD
- Used in research related to salt-sensitive hypertension and neurodegenerative diseases
eMolecules Ambeed (R)-3-Methoxypyrrolidine 5g 589946567 A848949 120099-60-7 MFCD09953439 101.149 C5H11NO
Ambeed (R)-3-Methoxypyrrolidine 5g 589946567 A848949 120099-60-7 MFCD09953439 101.149 C5H11NO
eMolecules ChemScene 25-Dibromopyridin-3-amine 25g 572179909 CS-0052143 90902-84-4 MFCD09266224 251.909 C5H4Br2N2
ChemScene 25-Dibromopyridin-3-amine 25g 572179909 CS-0052143 90902-84-4 MFCD09266224 251.909 C5H4Br2N2
Medchemexpress LLC Iadademstat (dihydrochloride) | 1431303-72-8 | 99.98% | 1 ML
Product Overview
Iadademstat (ORY-1001) is a highly potent, orally active, and selective LSD1 (KDM1A) inhibitor that exhibits antileukemic activity. It is intended for research use, particularly in studies concerning relapsed or refractory acute myeloid leukemia.Features and Benefits
- Highly potent, orally active, and selective LSD1 (KDM1A) inhibitor.
- Exhibits antileukemic activity.
- Can be used for research on relapsed or refractory acute myeloid leukemia.
- Inhibits the proliferation of cancer cells (H1299 and A549), arrests the cell cycle at G1 phase, and induces apoptosis in vitro.
- Decreases glycolysis in H1299 and A549 cells by reducing HK2 protein levels in vitro.
- Demonstrates antitumor activity and increases survival rate in glioblastoma xenograft mouse models in vivo.
TARGETMOL CHEMICALS INC Pivmecillinam hydrochloride
Also available in 1 mL, 5 mg, 10 mg, 25 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Pivmecillinam hydrochloride (FL-1039 hydrochloride) is an orally active prodrug of mecillinam, an extended-spectrum penicillin antibiotic effective against gram-negative organisms, and is used as a substitute for amdinocillin. Purity 99.86%
eMolecules ChemBridge - BB methyl 14-oxazepane-6-carboxylate hydrochloride 5g 446224282 4038104 95.000 2149643-75-2 MFCD28891946 195.640 C7H14ClNO3
ChemBridge - BB methyl 14-oxazepane-6-carboxylate hydrochloride 5g 446224282 4038104 95.000 2149643-75-2 MFCD28891946 195.640 C7H14ClNO3
TARGETMOL CHEMICALS INC TANDOSPIRONE CITRATE 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Tandospirone citrate (SM-3997 citrate) is a potent and selective 5-HT1A receptor partial agonist (Ki 27 nM)purity: 99%
Selleck Chemical LLC Ksg hydrochloride hydrate
Kasugamycin (Ksg) hydrochloride hydrate an antibiotic which binds both the 30S and 70S ribosome specifically inhibits translation initiation of canonical but not of leaderless messenger RNAs
Selleck Chemical LLC MPTP hydrochloride S4732-100mg
MPTP hydrochloride is a dopaminergic neurotoxin and cause selective destruction of dopaminergic neurons in animal models of parkinsonism MPTP hydrochloride induces apoptosis MPTP hydrochloride can be used to induce animal models of Parkinson s disease
Medchemexpress LLC 4,4'-(4-methyl-5-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-1H-pyrazole-1,3-diyl)diphenol hydrochloride | 2863676-89-3 | MFCD34676763 | 99.3% | 506.04 g/mol | C29H32ClN3O3 | 1 ML
MPP hydrochloride is a potent, selective estrogen receptor (ER) modulator used in in vitro and in vivo research to probe ERα activity. It is supplied as a white to off-white solid and as a ready-to-use 10 mM solution in DMSO (1 mL). Reported purity is 99.28% and molecular weight is 506.04 g/mol (C29H32ClN3O3).
- Potent, selective ER modulator for ERα studies.
- Available as a solid or 10 mM solution in DMSO.
- High reported purity (99.28%).
- Suitable for cellular and animal model experiments.
- Storage recommendations for solid and solution provided.
eMolecules ChemScene 1-(Thiazol-4-yl)prop-2-en-1-amine 1g 811575709 CS-0778843 1519434-65-1 MFCD23916855 140.200 C6H8N2S
ChemScene 1-(Thiazol-4-yl)prop-2-en-1-amine 1g 811575709 CS-0778843 1519434-65-1 MFCD23916855 140.200 C6H8N2S
Selleck Chemical LLC Benactyzine hydrochloride S3701-25mg
Benactyzine hydrochloride is a centrally acting muscarinic antagonist It is used as an antidepressant in the treatment of depression and associated anxiety
![Medchemexpress LLC 1H-Pyrrolo[2,3-b]pyridine, 2,3-dihydro- | 10592-27-5 | 959770 | 100.0% | 120.16 | 25 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000402770-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 1H-Pyrrolo[2,3-b]pyridine, 2,3-dihydro- | 10592-27-5 | 959770 | 100.0% | 120.16 | 25 G
2,3-Dihydro-7-azaindole (7-Azaindoline) is a biochemical reagent suitable for life science research. It can be utilized as a biological material or organic compound and is intended for research use only.
- Can be used as a biological material or organic compound
- Intended for life science related research
- Ships as a solid
- Appears white to off-white
- Storage conditions specified for solid and in solvent
Medchemexpress LLC 9-fluoro-11beta,17,21-trihydroxy-16alpha-methylpregn-4-ene-3,20-dione | 426-17-5 | MFCD22683747 | 5mg
1 2-Dihydro dexamethasone is a Dexamethasone (HY-14648) impurity
AdipoGen Verapamil hydrochloride
Chemical. CAS 152-11-4. Formula C27H38N2O4 . HCl. MW 491.06. Synthetic Verapamil hydrochloride is an alpha-adrenergic receptor alpha-AR antagonist and calcium channel protein inhibitor that blocks the L-type Ca2 channels in smooth and cardiac muscle cells. Verapamil is an antiarrhythmic agent and vasodilator known to reduce the renal clearance of digoxin and induce apoptosis in primary and metastatic colon adenocarcinoma human cell lines in vitro. It has been observed that verapamil can induce currents by itself, presumably by acting on the potassium and chloride leakage. Verapamil has also been used as an inhibitor of drug efflux pump proteins such as Mdr P-glycoprotein. Verapamil is a substrate of CYP3A4 and CYP2C6. It is also used in fluorescent cell sorting for DNA content, as it blocks efflux of a variety of DNA-binding fluorophores such as Hoechst 33342. Recent research has shown verapamil to be an effective treatment for diabetes in animal models.