Oxazinanes
TARGETMOL CHEMICALS INC CERDULATINIB HYDROCHLORI 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Cerdulatinib hydrochloride (PRT2070 hydrochloride) is an oral active multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk respectively. Also inhibits 19 other tested kinases with IC50 less than 200 nM. purity: 99%
eMolecules 885693-20-9 | 1-Boc-5,6-dihydro-2H-pyridine-3-boronic acid pinacol ester | Synthonix - Stock | MFCD10697911 | 309.210 | C16H28BNO4 | 97.000 | CC(C)(C)OC(=O)N1CCC=C(C1)B1OC(C)(C)C(C)(C)O1 | 10g | 525911807
1-Boc-5,6-dihydro-2H-pyridine-3-boronic acid pinacol ester | Synthonix - Stock | 885693-20-9 | MFCD10697911 | 309.210 | C16H28BNO4 | 97.000 | CC(C)(C)OC(=O)N1CCC=C(C1)B1OC(C)(C)C(C)(C)O1 | 10g | 525911807
Selleck Chemical LLC Tacrine hydrochloride hydrate S3639-25mg
Tacrine (Tetrahydroaminacrine Tetrahydroaminoacridine) is a centerally active cholinesterase inhibitor that has been used to counter the effects of muscle relaxants as a respiratory stimulant and in the treatment of Alzheimer s disease and other central nervous system disorders It also acts as a histamine N-methyltransferase inhibitor
TARGETMOL CHEMICALS INC Protriptyline hydrochloride
Also available in 1 mL, 10 mg, 25 mg and bulk. Please contact Fisher for quotes. Protriptyline Hydrochloride is the hydrochloride salt form of protriptyline, a tricyclic secondary amine with an antidepressant property. Protriptyline hydrochloride (Protriptyline HCl) blocks the re-uptake of norepinephrine and serotonin by nerve terminals, thereby increasing available norepinephrine and serotonin. In addition, this agent exhibits anticholinergic activity. Purity 99.98%
Selleck Chemical LLC Ligustrazine hydrochloride S3775-25mg
Ligustrazine hydrochloride (Tetramethylpyrazine Tetrapyrazine) is a chemical compound found in natto and in fermented cocoa beans with anti-inflammation antioxidant antiplatelet and antiapoptosis activities
Medchemexpress LLC Bomedemstat dihydrochloride | 99.6% | 592.54 | 100 MG
Bomedemstat dihydrochloride is an orally active and irreversible lysine-specific demethylase 1 (LSD1) inhibitor. It increases H3K4 and H3K9 methylation, altering gene expression. This compound exhibits anti-cancer activities by inhibiting cancer cell proliferation and inducing apoptosis.
- Increases H3K4 and H3K9 methylation
- Alters gene expression
- Inhibits cancer cell proliferation
- Induces apoptosis
Medchemexpress LLC Bomedemstat dihydrochloride | 99.55% | 592.54 | 25 MG
Bomedemstat dihydrochloride is an orally active and irreversible lysine-specific demethylase 1 (LSD1) inhibitor. It increases H3K4 and H3K9 methylation, which then alters gene expression. This compound exhibits anti-cancer activities by inhibiting cancer cell proliferation and inducing apoptosis, and is being investigated in multiple clinical trials.
- Selectively inhibits proliferation of Jak2V617F cells
- Induces apoptosis via BCL-XL and PUMA in a TP53-dependent manner
- Leads to cell cycle arrest in SET-2 cells
- Normalizes or improves blood cell counts in Mx-Jak2V617F mice
- Reduces spleen volumes and restores normal splenic architecture in animal models
Medchemexpress LLC 13,14-Dihydro-15-keto-PGE2 | 363-23-5 | 352.47 | 1 MG
13,14-Dihydro-15-keto-PGE2 participates in *Bifidobacterium animalis* F1-7 to alleviate opioid-induced constipation by 5-HT pathway.
- Targets endogenous metabolite and 5-HT receptor
- Participates in metabolic enzyme/protease, GPCR/G protein, and neuronal signaling pathways
- Stored as a solution at -20°C for up to 2 years