Oxazinanes
Apexbio Technology LLC Jatrorrhizine-Hydrochloride
Jatrorrhizine Hydrochloride (CAS No 960383-96-4) is a protoberberine alkaloid with significant biomedical research interest due to its potential therapeutic applications Originating from the plant Coptis chinensis jatrorrhizine is known for influencing key biological pathways including inhibition of the NF- B signaling pathway which is crucial in inflammation and cancer proliferation Its activity is commonly observed in the nanomolar to low micromolar range in vitro indicating potent efficacy at low concentrations Typical research applications include studies involving cell models and animal studies particularly focusing on anti-inflammatory and anticancer effects Moreover it is frequently utilized in drug screening assays to explore novel therapeutic agents Experimental concentrations typically depend on the specific research design allowing flexibility in determining its utility across various experimental setups
Medchemexpress LLC 3-Amino-2-oxazolidinone (AOZ) | 80-65-9 | 98.0% | 102.09 | 50 MG
3-Amino-2-oxazolidinone (AOZ) is a metabolite of Furazolidone and is used as an indicator for furazolidone residues in vivo. This orally active product inhibits monoamine oxidase (MAO) through its metabolite in rat brain and liver, increasing levels of monoamine neurotransmitters like norepinephrine and dopamine, and lowering blood pressure in renal hypertensive rats.
- Used as an indicator for furazolidone residues
- Orally active
- Increases levels of monoamine neurotransmitters
- Lowers blood pressure in renal hypertensive rats
Medchemexpress LLC 3-Amino-2-oxazolidinone-d4 (AOZ-d4) | 1188331-23-8 | 99.9% | 106.12 | 1 MG
3-Amino-2-oxazolidinone-d4 (AOZ-d4) is a deuterium labeled version of 3-Amino-2-oxazolidinone (HY-W012982). 3-Amino-2-oxazolidinone (AOZ) is a metabolite of Furazolidone (HY-B1336) and serves as an indicator of furazolidone residues in vivo. It is orally active and can be used as a tracer or as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. The product appears as a white to off-white solid. It is for research use only and not sold to patients.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC 3-Amino-2-oxazolidinone-d4 | 1188331-23-8 | 99.9% | 106.12 | 5 MG
3-Amino-2-oxazolidinone-d4 (AOZ-d4) is a deuterium labeled 3-Amino-2-oxazolidinone, which is the metabolite of Furazolidone. 3-Amino-2-oxazolidinone is always detected as an indicator of furazolidone residues in vivo and is orally active. It can be used as a tracer or as an internal standard for quantitative analysis.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Orally active
Apexbio Technology LLC AMODIAQUINE-HYDROCHLORIDE
Amodiaquine hydrochloride (CAS No 69-44-3) is an antimalarial agent primarily employed in biomedical research to explore its antiprotozoal properties and mechanisms of action Originating from the class of 4-aminoquinolines it acts by inhibiting heme polymerase disrupting heme detoxification in plasmodium parasites Its in vitro activity has been reported in the nanomolar to low micromolar range making it potent in various experimental settings Amodiaquine hydrochloride is frequently utilized in cell models and animal studies to evaluate its efficacy and safety profile and in drug screening assays to identify potential therapeutic candidates Experimental concentrations typically depend on the specific research design ensuring applicability across a range of scientific investigations
Apexbio Technology LLC CLINAFLOXACIN-HYDROCHLORIDE
Clinafloxacin (hydrochloride) (CAS No 105956-99-8) is an investigational antibacterial agent belonging to the fluoroquinolone class known for its broad-spectrum activity Originating from chemical modifications to enhance antibacterial efficacy it targets bacterial DNA gyrase and topoisomerase IV crucial enzymes for DNA replication and transcription Clinafloxacin exhibits potent antibacterial activity in the nanomolar to low micromolar range against various gram-positive and gram-negative bacteria It is frequently used in cell models and animal studies to evaluate antibacterial efficacy and resistance mechanisms Additionally it is utilized in drug screening assays to explore new therapeutic options for bacterial infections Experimental concentrations typically depend on the specific research design allowing flexibility in applications across different models and conditions
Apexbio Technology LLC CLINAFLOXACIN-HYDROCHLORIDE
Clinafloxacin (hydrochloride) (CAS No 105956-99-8) is an investigational antibacterial agent belonging to the fluoroquinolone class known for its broad-spectrum activity Originating from chemical modifications to enhance antibacterial efficacy it targets bacterial DNA gyrase and topoisomerase IV crucial enzymes for DNA replication and transcription Clinafloxacin exhibits potent antibacterial activity in the nanomolar to low micromolar range against various gram-positive and gram-negative bacteria It is frequently used in cell models and animal studies to evaluate antibacterial efficacy and resistance mechanisms Additionally it is utilized in drug screening assays to explore new therapeutic options for bacterial infections Experimental concentrations typically depend on the specific research design allowing flexibility in applications across different models and conditions
![Aobchem Ethanone 2-methoxy-1-[2-(trifluoromethyl)phenyl]- | ≥95% | CAS 1342027-89-7 | C10H9F3O2 | 250mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000905171.png-250.jpg)
Aobchem Ethanone 2-methoxy-1-[2-(trifluoromethyl)phenyl]- | ≥95% | CAS 1342027-89-7 | C10H9F3O2 | 250mg
Ethanone 2-methoxy-1-[2-(trifluoromethyl)phenyl]- | ≥95% | CAS 1342027-89-7 | C10H9F3O2 | 250mg
Apexbio Technology LLC Trigonelline-Hydrochloride
Trigonelline Hydrochloride (CAS No 6138-41-6) is a compound commonly studied in the field of biomedical research due to its potential therapeutic benefits and origins in plants such as fenugreek It operates through mechanisms involving modulation of glucose metabolism and the inhibition of protein glycation impacting pathways related to diabetes and neurodegenerative diseases In vitro activity assessments frequently indicate efficacy in the nanomolar to low micromolar range showcasing its potential as a bioactive agent Typical applications include its use in various cell models to study cellular metabolism as well as in animal studies for evaluating potential treatments for metabolic disorders It is also employed in drug screening panels to identify compounds that could mitigate oxidative stress Experimental concentrations typically depend on the specific research design reflecting its diverse applicability and the ongoing exploration of its pharmacological properties
![Aobchem [4-(Oxan-4-yloxy)phenyl]boronic acid | ≥95% | CAS 279261-92-6 | C11H15BO4 | 250mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000905468.png-250.jpg)
Aobchem [4-(Oxan-4-yloxy)phenyl]boronic acid | ≥95% | CAS 279261-92-6 | C11H15BO4 | 250mg
[4-(Oxan-4-yloxy)phenyl]boronic acid | ≥95% | CAS 279261-92-6 | C11H15BO4 | 250mg
Apexbio Technology LLC TRIMETAZIDINE-HYDROCHLORIDE
Trimetazidine (hydrochloride) (CAS No 13171-25-0) is a pharmacological agent primarily studied in the cardiovascular research field Originating from anti-ischemic drug development it functions by optimizing cellular metabolism under hypoxic conditions predominantly through the inhibition of long-chain 3-ketoacyl-CoA thiolase in the cardiac mitochondrial beta-oxidation pathway This action shifts fatty acid oxidation to glucose oxidation enhancing myocardial glucose consumption and efficiency during ischemic episodes Common in vitro activity occurs in the nanomolar to low micromolar range Trimetazidine is frequently used in various experimental applications including cell models like cardiomyocytes animal studies investigating myocardial protection and drug screening for cardiovascular therapies Experimental concentrations typically depend on the specific research design enabling a tailored approach to exploring its cardioprotective effects in different contexts