Oxazinanes
Medchemexpress LLC Dihydrodutasteride | 164656-22-8 | MFCD24386648 | 99.7% | C27H32F6N2O2 | 10MG
Dihydrodutasteride is a metabolite of dutasteride used as a research reagent for studies of 5α-reductase activity and dutasteride metabolism. It is supplied as a white to off-white solid intended for laboratory research use only; not for human or veterinary use.
- High purity: 99.7% (LCMS)
- Molecular formula C27H32F6N2O2 and molecular weight 530.55 g/mol
- Appearance: white to off-white solid
- Solubility ≥2.5 mg/mL (≈4.71 mM) in solvent
- Intended for research use only, not for human or veterinary use
Medchemexpress LLC 7,8-dihydro-2,5(1H,6H)-quinolinedione | 15450-69-8 | MFCD00766821 | 99.9% | 163.17 g/mol | C9H9NO2 | 1 G
7,8-Dihydro-2,5(1H,6H)-quinolinedione is a small-molecule research chemical used in biochemical and pharmacological studies. It is supplied as a light brown to light yellow solid, and the manufacturer's certificate of analysis reports high purity suitable for research applications.
- Small-molecule quinolinedione for biochemical and pharmacological research.
- High purity reported in supplier certificate of analysis.
- Light brown to light yellow solid, convenient for handling and storage.
- Molecular weight 163.17 g/mol; formula C9H9NO2.
- Documented as a positive inotropic agent in the literature.
- Provided with batch-specific certificate of analysis for traceability.
Medchemexpress LLC SAG (hydrochloride) | 2095432-58-7 | 99.91% | 1 MG
SAG hydrochloride is a potent Smoothened (Smo) receptor agonist with an EC50 of 3 nM and a Kd of 59 nM. It activates the Hedgehog signaling pathway and counteracts Cyclopamine inhibition of Smo.
- Induces firefly luciferase expression in Shh-LIGHT2 cells with an EC50 of 3 nM.
- Competes for the binding of BODIPY-cyclopamine to Smo-expressing Cos-1 cells, showing a dissociation constant (Kd) of 59 nM.
- Increases SMO mRNA and protein expression in MDAMB231 cells.
- Increases CAXII mRNA expression in MDAMB231 cells under normoxic and hypoxic conditions.
- Increases MDAMB231 cell migration.
- Promotes osteogenesis and significantly increases BV/TV in CD-1 mice.
- Induces pre-axial polydactyly and increases Gli1 and Gli2 mRNA expression in the limb bud in mice.
Medchemexpress LLC ML204 hydrochloride | 2070015-10-8 | 99.7% | 1 ML
ML204 hydrochloride is a novel, potent, and selective TRPC4/TRPC5 channel inhibitor.
- Potent and selective TRPC4/TRPC5 channel inhibitor.
- Exhibits at least 19-fold selectivity against TRPC6.
- No appreciable effect on other TRP channels.
- Does not affect voltage-gated sodium, potassium, or Ca2+ channels.
Medchemexpress LLC 4-Phenyl-7,8-dihydroxycoumarin | 842-01-3 | 99.4% | 10 MG
4-Phenyl-7,8-dihydroxycoumarin is a coumarin derivative for research use only, and can be used for bronchiectasis research.
- Chemical formula: C15H10O4
- Molecular weight: 254.24
- Appearance: Solid, off-white to yellow
- Solubility: 100 mg/mL in DMSO
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
- Related disease areas: Neurological, Eye or Ear Disease, Inflammation or Immune System Disease, Neurodegenerative Disease, Parkinson's Disease
- Signaling pathways: Inflammation/Immunology, Metabolic Enzyme/Protease, Neuronal Signaling, COMT
Aobchem 1 2-Dihydro- -methyl-5-acenaphthylenemethanol | ≥95% | CAS 2346-72-7 | C14H14O | 500mg
1 2-Dihydro- -methyl-5-acenaphthylenemethanol | ≥95% | CAS 2346-72-7 | C14H14O | 500mg
Aobchem (6-Cyanonaphthalen-2-yl)boronic acid | ≥95% | CAS 220299-56-9 | C11H8BNO2 | 500mg
(6-Cyanonaphthalen-2-yl)boronic acid | ≥95% | CAS 220299-56-9 | C11H8BNO2 | 500mg
Aobchem -Cyclohexyl-1 2-dihydro-5-acenaphthylenemethanol | 95% | CAS 1711457-29-2 | C19H22O | 1g
-Cyclohexyl-1 2-dihydro-5-acenaphthylenemethanol | 95% | CAS 1711457-29-2 | C19H22O | 1g
Aobchem 1 2-Dihydro- -methyl-5-acenaphthylenemethanol | ≥95% | CAS 2346-72-7 | C14H14O | 250mg
1 2-Dihydro- -methyl-5-acenaphthylenemethanol | ≥95% | CAS 2346-72-7 | C14H14O | 250mg
Aobchem (6-Cyanonaphthalen-2-yl)boronic acid | ≥95% | CAS 220299-56-9 | C11H8BNO2 | 250mg
(6-Cyanonaphthalen-2-yl)boronic acid | ≥95% | CAS 220299-56-9 | C11H8BNO2 | 250mg
![Aobchem 6 -Bromo-1 2 -dihydrospiro[cyclopropane-1 3 -[3H]indole] | ≥95% | CAS 1379360-39-0 | C10H10BrN | 250mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5001038632.png-250.jpg)
Aobchem 6 -Bromo-1 2 -dihydrospiro[cyclopropane-1 3 -[3H]indole] | ≥95% | CAS 1379360-39-0 | C10H10BrN | 250mg
6 -Bromo-1 2 -dihydrospiro[cyclopropane-1 3 -[3H]indole] | ≥95% | CAS 1379360-39-0 | C10H10BrN | 250mg
![Aobchem 6 -Bromo-1 2 -dihydrospiro[cyclopropane-1 3 -[3H]indole] | ≥95% | CAS 1379360-39-0 | C10H10BrN | 5g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5001038634.png-250.jpg)
Aobchem 6 -Bromo-1 2 -dihydrospiro[cyclopropane-1 3 -[3H]indole] | ≥95% | CAS 1379360-39-0 | C10H10BrN | 5g
6 -Bromo-1 2 -dihydrospiro[cyclopropane-1 3 -[3H]indole] | ≥95% | CAS 1379360-39-0 | C10H10BrN | 5g
Aobchem 4-Bromo-6-fluoro-2-methyl-2H-indazole | ≥97% | CAS 1425932-77-9 | C8H6BrFN2 | 5g
4-Bromo-6-fluoro-2-methyl-2H-indazole | ≥97% | CAS 1425932-77-9 | C8H6BrFN2 | 5g