Oxolanes
Chem-Impex International, Inc. Diacetone-D-glucose | 14686-89-6 | MFCD00005544 | 100G
Diacetone-D-glucose, 14686-89-6, MFCD00005544, 100G
Medchemexpress LLC KTX-582 intermediate-2 | 2434850-07-2 | 495.37 g/mol | C21H27BrN4O5 | 25 MG
KTX-582 intermediate-2 is a synthetic chemical intermediate used in the preparation of KTX-582 and for antibody-drug conjugate (ADC) construction. It is used in medicinal chemistry applications related to IRAK4 degrader development.
- Intermediate for synthesis and ADC preparation.
- CAS number 2434850-07-2.
- Molecular formula C21H27BrN4O5.
- Molecular weight 495.37 g/mol.
- Sold in small research quantities; supplier catalog indicates a 25 MG package.
Medchemexpress LLC Sorbitan trioleate 2.5kg
Sorbitan trioleate is an orally active nonionic surfactant with low toxicity (LD 200 mg/kg) Sorbitan trioleate can be used as an excipient such as surfactant emulsifier lubricant wetting agent dispersant thickener defoamer Pharmaceutical excipients or pharmaceutical auxiliaries refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations which can improve the stability solubility and processability of pharmaceutical preparations Pharmaceutical excipients also affect the absorption distribution metabolism and elimination (ADME) processes of co-administered drugs[1][2]
Medchemexpress LLC RK-582 | 2171388-28-4 | 98.05% | 510.60 | 50 MG
RK-582 is a tankyrase inhibitor, antitumor agent, and orally bioavailable growth inhibitor. It has an IC50 of 36.1 nM against human tankyrase-1 and 39.2 nM against human tankyrase-2. In APC-mutated colorectal cancer cells, sensitivity to RK-582 correlates with the level of active β-catenin, while drug resistance is associated with PIK3CA mutation. RK-582 can be used for the research of colorectal cancer.
- Tankyrase inhibitor
- Antitumor agent
- Orally bioavailable growth inhibitor
- IC50 of 36.1 nM against human tankyrase-1
- IC50 of 39.2 nM against human tankyrase-2
- Correlates with active β-catenin levels in APC-mutated colorectal cancer cells
- Useful for colorectal cancer research
Chem-Impex International, Inc. Diacetone-D-glucose | 14686-89-6 | MFCD00005544 | 25G
Diacetone-D-glucose, 14686-89-6, MFCD00005544, 25G
Sigma Aldrich Fine Chemicals Biosciences Span(R) 60 | Purity: 45-55% (GC) | 1338-41-6 | MFCD00005366 | 1KG
Span(R) 60 | Purity: 45-55% (GC) | 1338-41-6 | MFCD00005366 | 1KG
Medchemexpress LLC Sorbitan trioleate 500g
Sorbitan trioleate is an orally active nonionic surfactant with low toxicity (LD 200 mg/kg) Sorbitan trioleate can be used as an excipient such as surfactant emulsifier lubricant wetting agent dispersant thickener defoamer Pharmaceutical excipients or pharmaceutical auxiliaries refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations which can improve the stability solubility and processability of pharmaceutical preparations Pharmaceutical excipients also affect the absorption distribution metabolism and elimination (ADME) processes of co-administered drugs[1][2]
Medchemexpress LLC KTX-582 intermediate-2 | 2434850-07-2 | 495.37 | C21H27BrN4O5 | 10 MG
KTX-582 intermediate-2 is a synthetic intermediate used in the preparation of IRAK4 degrader molecules and for antibody-drug conjugate (ADC) synthesis. Supplied for research and synthetic applications.
- Used as a synthetic intermediate for IRAK4 degrader development
- Molecular weight 495.37
- Chemical formula C21H27BrN4O5
- CAS number 2434850-07-2
- Storage: 4°C sealed, away from moisture; in solvent: -80°C for 6 months, -20°C for 1 month