Piperazines
![eMolecules 250383-80-3 | [2-(4-METHYL-1-PIPERAZINYL)PHENYL]BORONIC ACID | AstaTech | MFCD22570819 | 220.080 | C11H17BN2O2 | 95.000 | CN1CCN(CC1)c1ccccc1B(O)O | 1g | 587288996](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502199471.JPG-250.jpg)
eMolecules 250383-80-3 | [2-(4-METHYL-1-PIPERAZINYL)PHENYL]BORONIC ACID | AstaTech | MFCD22570819 | 220.080 | C11H17BN2O2 | 95.000 | CN1CCN(CC1)c1ccccc1B(O)O | 1g | 587288996
[2-(4-METHYL-1-PIPERAZINYL)PHENYL]BORONIC ACID | AstaTech | 250383-80-3 | MFCD22570819 | 220.080 | C11H17BN2O2 | 95.000 | CN1CCN(CC1)c1ccccc1B(O)O | 1g | 587288996
Medchemexpress LLC JAK1-IN-8 | 1973485-18-5 | 95.0% | 442.51 | 50 MG
JAK1-IN-8 is a potent JAK1 inhibitor (IC50<500 nM), identified as compound 28 and extracted from patent WO2016119700A1. It is intended for research use only.
- Potent JAK1 inhibitor (IC50<500 nM)
- Compound 28 from patent WO2016119700A1
- Formula: C22H23FN4O3S
- Appearance: White to off-white solid
- Solubility in DMSO: 125 mg/mL (282.48 mM)
- Storage (powder): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC Ranolazine-d8 | 1092804-88-0 | 99.8% | 1 MG
Ranolazine-d8 is the deuterium labeled Ranolazine. Ranolazine is an anti-angina agent that inhibits the late phase of inward sodium current without affecting heart rate or blood pressure. It is also a partial fatty acid oxidation inhibitor.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC HY-17401 200mg Medchemexpress, Ranolazine (dihydrochloride) CAS:95635-56-6 Purity:>98%
Medchemexpress, HY-17401 200mg Ranolazine (dihydrochloride) CAS:95635-56-6 Ranolazine dihydrochloride (CVT 303 dihydrochloride) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP). Ranolazine dihydrochloride is also a partial fatty acid oxidation inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Chemscene ChemScene | BIBF 1202 | 10MG | CS-3025 | 0.98 | 894783-71-2| | 525.6
ChemScene | BIBF 1202 | 10MG | CS-3025 | 0.98 | 894783-71-2| | 525.6
Medchemexpress LLC HY-B0280 100mg Medchemexpress, Ranolazine CAS:95635-55-5 Purity:>98%
Medchemexpress, HY-B0280 100mg Ranolazine CAS:95635-55-5 Ranolazine (CVT 303) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP). Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-70027 10mg Medchemexpress, p53 and MDM2 proteins-interaction-inhibitor (chiral) CAS:939981-37-0 Purity:>98%
Medchemexpress, HY-70027 10mg p53 and MDM2 proteins-interaction-inhibitor (chiral) CAS:939981-37-0 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Ranolazine-d8 | 1092804-88-0 | 99.8% | 5 MG
Ranolazine-d8 is the deuterium labeled Ranolazine, an anti-angina agent that inhibits the late phase of inward sodium current without affecting heart rate or blood pressure. It is also a partial fatty acid oxidation (FAO) inhibitor. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Inhibits the late phase of inward sodium current
- Does not affect heart rate or blood pressure
- Acts as a partial fatty acid oxidation (FAO) inhibitor
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC JAK1-IN-8 | 1973485-18-5 | MFCD30530428 | 95.0% | C22H23FN4O3S | 10MG
JAK1-IN-8 is a small-molecule research compound reported as a potent Janus kinase 1 (JAK1) inhibitor (IC50 < 500 nM). It corresponds to compound 28 described in patent WO2016119700A1 and is provided as a white to off-white solid for in vitro research applications. Chemical identifiers include CAS 1973485-18-5 and formula C22H23FN4O3S.
- Potent JAK1 inhibition (IC50 < 500 nM).
- Suitable for JAK/STAT pathway and target validation studies.
- Provided as a white to off-white solid for laboratory use.
- Purity typically 95.0% by HPLC.
- Molecular weight 442.51 g/mol; formula C22H23FN4O3S.
- Available in multiple small-scale quantities for research.
- For research use only; not for human therapeutic use.
Medchemexpress LLC Dexrazoxane | 24584-09-6 | 99.88% | 10 MM 1 ML
Dexrazoxane is an intracellular iron chelating agent that reduces the formation of superoxide radicals. It exhibits cardioprotective, anti-inflammatory, antioxidant, anti-tumor, and neuroprotective activities. It inhibits ferroptosis of H9c2 cells by inhibiting HMGB1 and induces DNA damage and apoptosis in human fibrosarcoma cells.
- Recommended storage for powder: -20°C for 3 years, 4°C for 2 years
- Recommended storage for in solvent: -80°C for 6 months, -20°C for 1 month
- Induces DNA breaks, ATF3 accumulation, DNA damage response, and apoptosis in human fibrosarcoma cells
- Inhibits ferroptosis of H9c2 cells by inhibiting HMGB1
- Plays a protective role in rat models of doxorubicin-induced cardiomyopathy
- Provides antioxidant and anti-inflammatory effects in rodent models of Parkinson's disease
Medchemexpress LLC L-Aspartyl-L-phenylalanine | 13433-09-5 | 98.0% | 280.28 | 5 G
L-Aspartyl-L-phenylalanine is a metabolite of aspartame that effectively inhibits angiotensin converting enzyme (ACE) purified from rabbit lungs. It is provided as a laboratory chemical for research purposes only.
- ACE inhibitor
- For research use only
Medchemexpress LLC L-Aspartyl-L-phenylalanine | 13433-09-5 | 98.0% | 280.28 | 1 G
L-Aspartyl-L-phenylalanine is a metabolite of aspartame that can inhibit angiotensin converting enzyme (ACE) purified from rabbit lungs with a Ki of 11 μM. This product is for research use only and appears as a white to off-white solid.
- Inhibits angiotensin converting enzyme (ACE)
- Ki of 11 μM against angiotensin converting enzyme
- Molecular weight: 280.28
- Molecular formula: C13H16N2O5
- CAS No.: 13433-09-5
- Stable under recommended storage conditions
- For research use only