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Filtered Search Results
Advanced Chemblocks Inc 1-Boc-3-hydroxymethyl-piperazine; 5G; 97%
Chemical Name: 1-Boc-3-hydroxymethyl-piperazine CAS: 301673-16-5 MW: 216.28 MDL Number: MFCD04115304 Category: piperazine Synonym: 1-Boc-3-hydroxymethyl-piperazine
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Aobchem AOBCHEM
5000872246 4-BUTOXY-2 6-DIMETHYLPHENYL
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Medchemexpress LLC 2'-O-(2-Methoxyethyl) inosine | 545374-76-3 | 973934 | C13H18N4O6 | 25 MG
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2'-O-(2-Methoxyethyl) inosine is a purine nucleoside analog known for its broad antitumor activity, especially against indolent lymphoid malignancies. Its mechanisms of action involve the inhibition of DNA synthesis and the induction of apoptosis.
- Purine nucleoside analog
- Broad antitumor activity
- Effective against indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
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![Medchemexpress LLC 2-(4-ethyl-piperazin-1-yl)-N-[4-(2-morpholinyl-4-oxo-4H-chromen-8-yl)-dibenzothiophenyl]-acetamide | 881375-00-4 | MFCD17214218 | ≥97.0% | 582.71 g/mol | C33H34N4O4S | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000222137.png-250.jpg)
Medchemexpress LLC 2-(4-ethyl-piperazin-1-yl)-N-[4-(2-morpholinyl-4-oxo-4H-chromen-8-yl)-dibenzothiophenyl]-acetamide | 881375-00-4 | MFCD17214218 | ≥97.0% | 582.71 g/mol | C33H34N4O4S | 5 MG
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KU-0060648 is a small-molecule, ATP-competitive dual inhibitor of phosphoinositide 3-kinases (PI3K) and DNA-dependent protein kinase (DNA-PK), used in research to probe PI3K/DNA-PK signaling and to enhance chemosensitivity in cancer models. Reported enzymatic IC50 values are PI3Kα 4 nM, PI3Kβ 0.5 nM, PI3Kγ 0.1 nM, PI3Kδ 0.594 nM, and DNA-PK 8.6 nM.
- Dual inhibition of PI3K and DNA-PK for pathway interrogation.
- Low nanomolar potency against multiple PI3K isoforms and DNA-PK.
- Suitable for use in in vitro and in vivo research studies.
- Available in small-mass quantities for dose-ranging experiments.
- Powder form with defined storage conditions to preserve stability.
- Well-characterized chemical identity and molecular properties.
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Aobchem AOBCHEM
5000872079 3-BROMO-5-METHYLPHENYL MORPH
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Aobchem AOBCHEM
5000872157 3-METHOXY-2 6-DIMETHYLPHENYL
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Sigma Aldrich Fine Chemicals Biosciences Buspirone Related Compound K United States Pharmacopeia (USP) Reference Standard | 1075-89-4 | 50MG
Buspirone Related Compound K United States Pharmacopeia (USP) Reference Standard | Mol Wt: 167.21 | 1075-89-4 | 50MG
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eMolecules 1073354-42-3 | 2-(4-BOC-Piperazino)pyridine-3-boronic acid, pinacol ester | Combi-Blocks | MFCD07781131 | 389.300 | C20H32BN3O4 | 97.000 | CC(C)(C)OC(=O)N1CCN(CC1)c1ncccc1B1OC(C)(C)C(C)(C)O1 | 5g | 117546497
2-(4-BOC-Piperazino)pyridine-3-boronic acid, pinacol ester | Combi-Blocks | 1073354-42-3 | MFCD07781131 | 389.300 | C20H32BN3O4 | 97.000 | CC(C)(C)OC(=O)N1CCN(CC1)c1ncccc1B1OC(C)(C)C(C)(C)O1 | 5g | 117546497
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eMolecules 852180-47-3 | 4-(4-Boc-Piperazino)benzylamine | Combi-Blocks | MFCD03791213 | 291.395 | C16H25N3O2 | 97.000 | CC(C)(C)OC(=O)N1CCN(CC1)c1ccc(CN)cc1 | 1g | 232337446
4-(4-Boc-Piperazino)benzylamine | Combi-Blocks | 852180-47-3 | MFCD03791213 | 291.395 | C16H25N3O2 | 97.000 | CC(C)(C)OC(=O)N1CCN(CC1)c1ccc(CN)cc1 | 1g | 232337446
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Aobchem AOBCHEM
5000863992 ETHYL 2- 2 4-DIMETHYLPHENYL -2
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Apexbio Technology LLC KX2-391 dihydrochloride 1038395-65-1 50mg
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KX2-391 dihydrochloride (CAS 1038395-65-1) is an orally bioavailable small molecule that inhibits Src tyrosine kinase through selective interaction with the peptide substrate binding site rather than the ATP-binding site By blocking this non-catalytic domain KX2-391 disrupts Src kinase-mediated signaling pathways involved in tumor cell proliferation and metastatic processes Src kinases are frequently upregulated in various malignancies underscoring their importance in cancer biology KX2-391 is widely utilized in preclinical studies investigating Src-driven mechanisms of oncogenesis and tumor progression
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Apexbio Technology LLC LDK378 dihydrochloride 1380575-43-8 10mg
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LDK378 dihydrochloride (CAS 1380575-43-8) is a potent inhibitor of anaplastic lymphoma kinase (ALK) a receptor tyrosine kinase in the insulin receptor superfamily Demonstrating an in vitro IC50 of 200 pM against ALK LDK378 also inhibits IGF-1R InsR and STK22D with IC50 values of 8 nM 7 nM and 23 nM respectively In cellular assays LDK378 suppresses proliferation of Ba/F3 cells expressing NPM-ALK and Karpas-299 human non-Hodgkin lymphoma cells with IC50 values of 22 8 nM and 26 nM This compound serves as a valuable tool for investigating ALK-driven signaling pathways and potential therapeutic strategies in oncology research
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Aobchem AOBCHEM
5000866194 N- 2-BROMO-4 5-DIMETHYLPHENYL
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Apexbio Technology LLC AO/PI Double Staining Kit 500T
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The AO/PI Double Staining Kit is a reagent kit enabling rapid detection of cell viability This kit provides two nuclear dyes Acridine Orange (AO) and Propidium Iodide (PI) AO can penetrate intact cell membranes and stain viable cells green During apoptosis chromosomes become condensed or fragmented into differently sized segments In this scenario AO stains apoptotic cells densely with yellow-green fluorescence or as yellow-green fragments The other nuclear dye PI cannot pass through intact cell membranes therefore it does not stain viable or apoptotic cells in red but stains cells with compromised membranes (e g necrotic cells) When using these two dyes in combination viable cells exhibit green fluorescence apoptotic cells show dense varied-size yellow-green or orange fluorescence and necrotic cells exhibit strong red fluorescence
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Aobchem AOBCHEM
5000861612 4-BROMO-3 5-DIMETHYLPHENYL ME
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