Piperazines

Aobchem AOBCHEM

5000924164 5-BROMO-2 4-DIMETHYLPHENYL 4

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Aobchem AOBCHEM

5000924214 5-BROMO-2 4-DIMETHYLPHENYL P

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Aobchem AOBCHEM

5000925036 1- 2 4-DIMETHYLPHENYL -1-BUTAN

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Medchemexpress LLC JAK1-IN-8 | 1973485-18-5 | 95.0% | 442.51 | 50 MG

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JAK1-IN-8 is a potent JAK1 inhibitor (IC50<500 nM), identified as compound 28 and extracted from patent WO2016119700A1. It is intended for research use only.

• Potent JAK1 inhibitor (IC50<500 nM)
• Compound 28 from patent WO2016119700A1
• Formula: C22H23FN4O3S
• Appearance: White to off-white solid
• Solubility in DMSO: 125 mg/mL (282.48 mM)
• Storage (powder): -20°C for 3 years, 4°C for 2 years
• Storage (in solvent): -80°C for 6 months, -20°C for 1 month

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Medchemexpress LLC HY-B0280 100mg Medchemexpress, Ranolazine CAS:95635-55-5 Purity:>98%

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Medchemexpress, HY-B0280 100mg Ranolazine CAS:95635-55-5 Ranolazine (CVT 303) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP). Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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Medchemexpress LLC HY-70027 10mg Medchemexpress, p53 and MDM2 proteins-interaction-inhibitor (chiral) CAS:939981-37-0 Purity:>98%

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Medchemexpress, HY-70027 10mg p53 and MDM2 proteins-interaction-inhibitor (chiral) CAS:939981-37-0 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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Medchemexpress LLC Ranolazine-d8 | 1092804-88-0 | 99.8% | 5 MG

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Ranolazine-d8 is the deuterium labeled Ranolazine, an anti-angina agent that inhibits the late phase of inward sodium current without affecting heart rate or blood pressure. It is also a partial fatty acid oxidation (FAO) inhibitor. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

• Inhibits the late phase of inward sodium current
• Does not affect heart rate or blood pressure
• Acts as a partial fatty acid oxidation (FAO) inhibitor
• Used as a tracer
• Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS

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Medchemexpress LLC JAK1-IN-8 | 1973485-18-5 | MFCD30530428 | 95.0% | C22H23FN4O3S | 10MG

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JAK1-IN-8 is a small-molecule research compound reported as a potent Janus kinase 1 (JAK1) inhibitor (IC50 < 500 nM). It corresponds to compound 28 described in patent WO2016119700A1 and is provided as a white to off-white solid for in vitro research applications. Chemical identifiers include CAS 1973485-18-5 and formula C22H23FN4O3S.

• Potent JAK1 inhibition (IC50 < 500 nM).
• Suitable for JAK/STAT pathway and target validation studies.
• Provided as a white to off-white solid for laboratory use.
• Purity typically 95.0% by HPLC.
• Molecular weight 442.51 g/mol; formula C22H23FN4O3S.
• Available in multiple small-scale quantities for research.
• For research use only; not for human therapeutic use.

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eMolecules​ 714272-27-2 | Medchem Express | Plinabulin | 5mg | 459606694 | HY-14444 | MFCD18074510 | 336.395 | C19H20N4O2

Medchem Express | Plinabulin | 5mg | 459606694 | HY-14444 | 714272-27-2 | MFCD18074510 | 336.395 | C19H20N4O2

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eMolecules​ 714272-27-2 | PLINABULIN | AstaTech336.395 | C19H20N4O2 | 95.000 | CC(C)(C)c1[nH]cnc1\C=c1/[nH]c(=O)\c(=C/c2ccccc2)[nH]c1=O | 25mg | 724431065

PLINABULIN | AstaTech | 714272-27-2336.395 | C19H20N4O2 | 95.000 | CC(C)(C)c1[nH]cnc1\C=c1/[nH]c(=O)\c(=C/c2ccccc2)[nH]c1=O | 25mg | 724431065

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Medchemexpress LLC MEDCHEMEXPRESS LLC

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5000770540 2 6-DI1-PYRAZOLYLP 1G

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Apexbio Technology LLC Dexrazoxane 24584-09-6 100mg

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Dexrazoxane is a cell-permeable iron chelator that suppresses intracellular superoxide radical generation via iron sequestration thereby exhibiting antioxidant activity Dexrazoxane exerts its biological effects primarily by modulating oxidative stress and ferroptosis pathways In cell-based studies including myocardial H9c2 cell models dexrazoxane inhibits ferroptosis by suppressing the HMGB1 pathway and induces DNA damage and apoptosis in various tumor cell lines Based on these pharmacological properties dexrazoxane holds research potential in the study of cardioprotective mechanisms tumor-related DNA damage responses ferroptosis and oxidative stress processes

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Aobchem AOBCHEM

5000966557 1- 2- 2-HYDROXYETHOXY -5- 2 4

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Aobchem AOBCHEM

5000966732 4-BROMO-2-FLUOROPHENYL MORPH

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