Piperidines

Active Motif UNC-2170

Active Motif's The DNA damage response protein 53BP1 utilizes its tandem tudor domain to recognize dimethylated lysine 20 on histone (H4K20me2), a modification associated with double-stranded DNA breaks. UNC-2170, identified by screening, was found to be a uM ligand for 53BP1 which also demonstrated at least 17-fold selectivity for 53BP1 over other methyl-lysine binding proteins. The compound functions as 53BP1 antagonist in cell lysates and suppresses class switch recombination in whole cells, a process requiring a functioning 53BP1 tudor domain.

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Chembridge Corporation 1-METHYLPIPERIDIN-4-AMINE

1-methylpiperidin-4-amine; CAS: 41838-46-4

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Enzo Life Sciences Alectinib. hydrochloride (50mg). CAS: 1256589-74-8

Alectinib hydrochloride is a selective anaplastic lymphoma kinase (ALK) inhibitor leading to inhibition of tumor cell proliferation and induction of cell death.  Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.

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Medchemexpress LLC HY-112167 5mg Medchemexpress, GDC-0575 CAS:1196541-47-5 Purity:>98%

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Medchemexpress, HY-112167 5mg GDC-0575 CAS:1196541-47-5 GDC-0575 (ARRY-575, RG7741) is a highly-selective oral small-molecule Chk1 inhibitor with an IC50 of 1.2 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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Medchemexpress LLC SHP099 hydrochloride, 1801747-11-4, MFCD30343849, 10 mg

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Molecular Formula: C16 H19 Cl2 N5 . Cl H, Molecular Weight: 388.728, 99.67%, Store in -20°C.

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eMolecules​ 625471-18-3 | (S)-1-Boc-3-aminopiperidine | Chem-Impex | MFCD01861219 | 200.282 | C10H20N2O2 | 98.000 | CC(C)(C)OC(=O)N1CCCC(N)C1 | 25g | 112759737

(S)-1-Boc-3-aminopiperidine | Chem-Impex | 625471-18-3 | MFCD01861219 | 200.282 | C10H20N2O2 | 98.000 | CC(C)(C)OC(=O)N1CCCC(N)C1 | 25g | 112759737

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Medchemexpress LLC Yya-021 | 144217-65-2 | 99.0% | 317.43 g/mol | C18H27N3O2 | 25 MG

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YYA-021 is a small-molecule CD4 mimic that inhibits HIV entry by competitively blocking the viral envelope glycoprotein interaction with CD4. It exhibits potent anti-HIV activity with low cytotoxicity and is supplied for research applications as a high-purity solid.

• Small-molecule CD4 mimic that blocks HIV entry.
• Demonstrates high anti-HIV activity with low cytotoxicity.
• High purity (≈99%) suitable for biochemical and cellular assays.
• Supplied as a white to off-white solid with multiple pack sizes.
• Storage recommendations support long-term stability for research use.

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Medchemexpress LLC Maraviroc | 376348-65-1 | MFCD09953791 | 50mg

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Maraviroc | Putity: 99.95% | MW: 513.67 | 376348-65-1 | MFCD09953791 | 50mg

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Chem-Impex International, Inc. 1-Boc-4-aminopiperidine | MFCD01076201 | 100G

1-Boc-4-aminopiperidine, MFCD01076201, 100G

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eMolecules​ 1159822-23-7 | N-CBZ-8-AZABICYCLO[3.2.1]OCTANE-3-CARBOXYLIC ACID | AstaTech | MFCD27940040 | 289.331 | C16H19NO4 | 97.000 | OC(=O)C1CC2CCC(C1)N2C(=O)OCc1ccccc1 | 1g | 112524949

N-CBZ-8-AZABICYCLO[3.2.1]OCTANE-3-CARBOXYLIC ACID | AstaTech | 1159822-23-7 | MFCD27940040 | 289.331 | C16H19NO4 | 97.000 | OC(=O)C1CC2CCC(C1)N2C(=O)OCc1ccccc1 | 1g | 112524949

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eMolecules​ 406216-02-2 | (R)-3-Aminopiperidin-2-one hydrochloride | ChemScene | MFCD09752974 | 150.610 | C5H11ClN2O | 97.000 | Cl.N[C@@H]1CCCNC1=O | 1g | 559780540

(R)-3-Aminopiperidin-2-one hydrochloride | ChemScene | 406216-02-2 | MFCD09752974 | 150.610 | C5H11ClN2O | 97.000 | Cl.N[C@@H]1CCCNC1=O | 1g | 559780540

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Selleck Chemical LLC Alectinib S2762-50mg

Alectinib is a potent ALK inhibitor with IC50 of 1 9 nM in cell-free assays sensitive to L1196M mutation and higher selectivity for ALK than PF-02341066 NVP-TAE684 and PHA-E429

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Chem-Impex International, Inc. Boc-4-aminopiperidine | MFCD00798171 | 5G

Boc-4-aminopiperidine, MFCD00798171, 5G

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eMolecules​ 3,8-DIAZABICYCLO[3.2.1]OCTAN-2-ONE, 3-METHYL- | 1434141-65-7 | MFCD27956942 | 0.25g

AstaTech | 3,8-DIAZABICYCLO[3.2.1]OCTAN-2-ONE, 3-METHYL- | 0.25g | 454129580 | P17880 | 95.000 | 1434141-65-7 | MFCD27956942 | 140.186 | C7H12N2O

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eMolecules​ 1400744-19-5 | [(3S)-1-methylpiperidin-3-yl]methanamine dihydrochloride | MFCD21641985 | 1g

Medchem Express | BL-1249 | 5mg | 495799677 | HY-108596 | 18200-13-0 | MFCD08276915 | 291.358 | C17H17N5

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