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Piperidines

Organic heterocyclic compounds that consist of a six-membered ring containing five carbon atoms and one nitrogen atom that forms an amine functional group.

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1

Medchemexpress LLC Serca2a activator 1 | 2139330-34-8 | 99.7% | 551.66 | C32H29N3O4S | 100MG
SDP

SERCA2a activator 1 is a small-molecule research compound that enhances the activity of the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase isoform 2a (SERCA2a), reducing phospholamban inhibition and improving cardiac contractile relaxation in experimental systems. It is supplied as a light yellow to yellow solid and is also available as a 10 mM solution in DMSO for laboratory use; intended for research use only.

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2

Medchemexpress LLC SERCA2a activator 1 (compound A) | 2139330-34-8 | 99.7% | 551.66 g/mol | C32H29N3O4S | 50MG
SDP

SERCA2a activator 1 is a small-molecule activator of the sarco/endoplasmic reticulum Ca2+-dependent ATPase 2a (SERCA2a). It reduces phospholamban-mediated inhibition and can enhance cardiac contractile and relaxation responses in preclinical models. The compound is supplied for research use as a high-purity solid and is also available as a DMSO solution for assay use.

  • Activates SERCA2a to improve calcium handling in cardiac models.
  • High purity: 99.7%.
  • Molecular weight: 551.66 g/mol.
  • Chemical formula: C32H29N3O4S.
  • Physical form: light yellow to yellow solid powder.
  • Available as powder and as a 10 mM solution in DMSO.
  • Storage: powder -20°C (up to 3 years) or 4°C (up to 2 years); in solvent -80°C (up to 6 months).

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3

Medchemexpress LLC 5'-benzyl-1'-butyl-N-(naphthalen-2-ylsulfonyl)-6'-oxo-1',6'-dihydro-[2,3'-bipyridine]-4-carboxamide | 2139330-34-8 | 99.7% | 551.66 | C32H29N3O4S | 10MG
SDP

SERCA2a activator 1 is a small-molecule research compound that activates the sarco/endoplasmic reticulum Ca2+-dependent ATPase 2a (SERCA2a), attenuates phospholamban inhibition, and is used in preclinical studies of cardiac function and heart failure.

  • Activates SERCA2a and enhances Ca2+-dependent ATPase activity.
  • Attenuates phospholamban inhibition to improve systolic and diastolic function in models.
  • Suitable for preclinical cardiac function and heart failure research.
  • High purity (99.7%) with molecular weight 551.66.
  • Available as powder and as a 10 mM solution in DMSO, multiple package sizes.
  • Recommended storage: powder -20°C (up to 3 years) or 4°C (up to 2 years); in solvent -80°C (6 months).

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4

Medchemexpress LLC 5'-benzyl-1'-butyl-N-(naphthalen-2-ylsulfonyl)-6'-oxo-1',6'-dihydro-[2,3'-bipyridine]-4-carboxamide | 2139330-34-8 | 99.5% | 551.66 g·mol⁻¹ | C32H29N3O4S | 5MG
SDP

SERCA2a activator 1 is a small-molecule activator of the sarco/endoplasmic reticulum Ca2+-dependent ATPase 2a (SERCA2a) used in preclinical cardiovascular research to attenuate phospholamban inhibition and enhance cardiac contractile function. Supplied for research use only.

  • Activates SERCA2a and attenuates phospholamban inhibition.
  • Used to enhance systolic and diastolic cardiac function in research models.
  • Molecular formula C32H29N3O4S.
  • Molecular weight 551.66 g·mol⁻¹.
  • Available in milligram quantities suitable for in vitro and in vivo studies.
  • Supplied for research use only; not for human or veterinary use.

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