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Carboxy-PTIO potassium salt (CAS 148819-94-7) is a small molecule recognized as a nitric oxide (NO) scavenger It reacts rapidly with NO converting it to nitrogen oxides and thereby reducing bioavailable NO levels In lipopolysaccharide-induced rat models administration of Carboxy-PTIO potassium salt has been shown to attenuate hypotension and decrease the incidence of endotoxic shock via NO clearance This compound is widely employed in studies investigating NO-related signaling pathways and the pathophysiological roles of aberrant NO production
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Carboxy-PTIO potassium salt (CAS 148819-94-7) is a small molecule recognized as a nitric oxide (NO) scavenger It reacts rapidly with NO converting it to nitrogen oxides and thereby reducing bioavailable NO levels In lipopolysaccharide-induced rat models administration of Carboxy-PTIO potassium salt has been shown to attenuate hypotension and decrease the incidence of endotoxic shock via NO clearance This compound is widely employed in studies investigating NO-related signaling pathways and the pathophysiological roles of aberrant NO production
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Carboxy-PTIO potassium is a potent nitric oxide (NO) scavenger that reacts quickly with NO to produce NO2. It can prevent hypotension and endotoxic shock by directly scavenging NO in a lipopolysaccharide-stimulated rat model.
Potent nitric oxide (NO) scavenger.
Reacts quickly with NO to produce NO2.
Can prevent hypotension and endotoxic shock through direct NO scavenging.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Carboxy-PTIO potassium is a potent nitric oxide (NO) scavenger that reacts quickly with NO to produce NO2. It can prevent hypotension and endotoxic shock by directly scavenging NO in a lipopolysaccharide-stimulated rat model. It is for research use only and not sold to patients.
Potent nitric oxide (NO) scavenger.
Can prevent hypotension and endotoxic shock.
In vitro, it significantly suppresses the stimulation of NO expression induced by Physalin A treatment and reverses decreased mTOR and p-mTOR levels with concomitant suppression of LC3 I to LC3 II conversions in A375-S2 cells.
In vivo, it improves hypotension, renal dysfunction, and survival rate in LPS-treated rats.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Carboxy-PTIO potassium is a potent nitric oxide (NO) scavenger that rapidly reacts with NO to produce NO2. It can prevent hypotension and endotoxic shock through its direct NO-scavenging action in a lipopolysaccharide-stimulated rat model. This compound is intended for research use only and is not sold to patients.
Potent nitric oxide (NO) scavenger
Reacts quickly with NO to produce NO2
Can prevent hypotension and endotoxic shock by scavenging NO in LPS-stimulated rat models
Significantly suppresses stimulation of NO expression induced by Physalin A treatment in vitro
Reduces Physalin A-induced cleavage of procaspase-3 and PARP, and down-regulates ICAD expression, diminishing DNA fragmentation in nuclei
Reverses decreased mTOR and p-mTOR levels induced by Physalin A, with concomitant suppression of LC3 I to LC3 II conversions in A375-S2 cells
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More