Pyridines and derivatives
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Medchemexpress LLC Lobendazole | 6306-71-4 | 99.5% | 100 MG
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Lobendazole is a potent anthelmintic compound recognized for its activity against various parasitic infections. It inhibits *Giardia intestinalis* strains and is available in high purity, making it suitable for research applications.
- Potent anthelmintic activity.
- Inhibits *Giardia intestinalis* strains.
- Available in high purity.
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Medchemexpress LLC Lobendazole | 6306-71-4 | 99.5% | 5 MG
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Lobendazole is a potent anthelmintic. Lobendazole inhibits Giardia intestinalis strains.
- Potent anthelmintic.
- Inhibits Giardia intestinalis strains.
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Medchemexpress LLC Lobendazole | 6306-71-4 | 99.49% | 25 MG
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Lobendazole is a potent anthelmintic that inhibits *Giardia intestinalis* strains. It is for research use only and not sold to patients.
- Potent anthelmintic
- Inhibits Giardia intestinalis strains
- White to off-white solid appearance
- Molecular weight: 205.21
- Formula: C10H11N3O2
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Medchemexpress LLC Ethyl N-(5-benzimidazolyl)carbamate | 6306-71-4 | MFCD00552813 | 99.5% | 205.21 g/mol | C10H11N3O2 | 10 MG
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Lobendazole is a benzimidazole-class anthelmintic supplied for research use. It inhibits Giardia intestinalis strains and is provided as a white to off-white solid with high chemical purity.
- Anthelmintic active against Giardia intestinalis strains.
- High purity (99.49%).
- Molecular weight 205.21 g/mol.
- Packaged as a compact 10 MG dose for laboratory use.
- White to off-white solid appearance.
- For research use only; not for human or veterinary use.
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1-Bromoisoquinoline 98.0+%, TCI America™
CAS: 1532-71-4 Molecular Formula: C9H6BrN Molecular Weight (g/mol): 208.058 MDL Number: MFCD00234478 InChI Key: YWWZASFPWWPUBN-UHFFFAOYSA-N Synonym: isoquinoline, 1-bromo,1-bromo-isoquinoline,bromoisoquinoline,zlchem 702,pubchem6211,acmc-1bqnj,1-bromoisoquinoline,abbypharma ap-12-10888 PubChem CID: 640963 IUPAC Name: 1-bromoisoquinoline SMILES: C1=CC=C2C(=C1)C=CN=C2Br
| PubChem CID | 640963 |
|---|---|
| CAS | 1532-71-4 |
| Molecular Weight (g/mol) | 208.058 |
| MDL Number | MFCD00234478 |
| SMILES | C1=CC=C2C(=C1)C=CN=C2Br |
| Synonym | isoquinoline, 1-bromo,1-bromo-isoquinoline,bromoisoquinoline,zlchem 702,pubchem6211,acmc-1bqnj,1-bromoisoquinoline,abbypharma ap-12-10888 |
| IUPAC Name | 1-bromoisoquinoline |
| InChI Key | YWWZASFPWWPUBN-UHFFFAOYSA-N |
| Molecular Formula | C9H6BrN |
4,4'-Dibromo-2,2'-bipyridyl 97.0+%, TCI America™
CAS: 18511-71-2 Molecular Formula: C10H6Br2N2 Molecular Weight (g/mol): 313.98 MDL Number: MFCD00667763 InChI Key: KIIHBDSNVJRWFY-UHFFFAOYSA-N Synonym: 4,4'-dibromo-2,2'-bipyridine,4-bromo-2-4-bromopyridin-2-yl pyridine,4,4'-dibromo-2,2'-bipyridyl,2,2'-bipyridine, 4,4'-dibromo,bpbb01,acmc-1bo83,4,4'-dibromo-2,2-bipyridine,4,4'-bromo-2,2'-bipyridine,4,4'-dibromo-2,2'-dipyridine,4,4'-dibromine-2,2'-bipyridine PubChem CID: 15569987 IUPAC Name: 4-bromo-2-(4-bromopyridin-2-yl)pyridine SMILES: C1=CN=C(C=C1Br)C2=NC=CC(=C2)Br
| PubChem CID | 15569987 |
|---|---|
| CAS | 18511-71-2 |
| Molecular Weight (g/mol) | 313.98 |
| MDL Number | MFCD00667763 |
| SMILES | C1=CN=C(C=C1Br)C2=NC=CC(=C2)Br |
| Synonym | 4,4'-dibromo-2,2'-bipyridine,4-bromo-2-4-bromopyridin-2-yl pyridine,4,4'-dibromo-2,2'-bipyridyl,2,2'-bipyridine, 4,4'-dibromo,bpbb01,acmc-1bo83,4,4'-dibromo-2,2-bipyridine,4,4'-bromo-2,2'-bipyridine,4,4'-dibromo-2,2'-dipyridine,4,4'-dibromine-2,2'-bipyridine |
| IUPAC Name | 4-bromo-2-(4-bromopyridin-2-yl)pyridine |
| InChI Key | KIIHBDSNVJRWFY-UHFFFAOYSA-N |
| Molecular Formula | C10H6Br2N2 |
3-Hydroxyisonicotinic Acid 98.0+%, TCI America™
CAS: 10128-71-9 Molecular Formula: C6H5NO3 Molecular Weight (g/mol): 139.11 MDL Number: MFCD00234165 InChI Key: JEHGATQUCUYHJL-UHFFFAOYSA-N Synonym: 3-hydroxyisonicotinic acid,3-hydroxy-4-pyridinecarboxylic acid,3-hydroxy-4-pyridinecarboxylicacid,4-pyridinecarboxylic acid, 3-hydroxy,3-hydroxy pyridine-4-carboxylic acid,3-hydroxyisonicontinic acid,pubchem16741,acmc-1bs5o,3-hydroxy-isonicotinic acid PubChem CID: 459503 IUPAC Name: 3-hydroxypyridine-4-carboxylic acid SMILES: C1=CN=CC(=C1C(=O)O)O
| PubChem CID | 459503 |
|---|---|
| CAS | 10128-71-9 |
| Molecular Weight (g/mol) | 139.11 |
| MDL Number | MFCD00234165 |
| SMILES | C1=CN=CC(=C1C(=O)O)O |
| Synonym | 3-hydroxyisonicotinic acid,3-hydroxy-4-pyridinecarboxylic acid,3-hydroxy-4-pyridinecarboxylicacid,4-pyridinecarboxylic acid, 3-hydroxy,3-hydroxy pyridine-4-carboxylic acid,3-hydroxyisonicontinic acid,pubchem16741,acmc-1bs5o,3-hydroxy-isonicotinic acid |
| IUPAC Name | 3-hydroxypyridine-4-carboxylic acid |
| InChI Key | JEHGATQUCUYHJL-UHFFFAOYSA-N |
| Molecular Formula | C6H5NO3 |
2-Chloro-4,6-dimethyl-3-pyridinecarbonitrile 98.0+%, TCI America™
CAS: 14237-71-9 Molecular Formula: C8H7ClN2 Molecular Weight (g/mol): 166.61 MDL Number: MFCD00051676 InChI Key: RETJKTAVEQPNMH-UHFFFAOYSA-N Synonym: 2-chloro-4,6-dimethylnicotinonitrile,2-chloro-3-cyano-4,6-dimethylpyridine,2-chloro-4,6-dimethyl-nicotinonitrile,2-chloro-4,6-dimethyl-3-pyridinecarbonitrile,3-pyridinecarbonitrile, 2-chloro-4,6-dimethyl,acmc-1azio,chlorodimethylnicotinonitrile,ksc496m6f,2-chloro-4,6-dimethyinicotinonitrile,4,6-dimethyl-2-chloro-nicotinonitrile PubChem CID: 223261 IUPAC Name: 2-chloro-4,6-dimethylpyridine-3-carbonitrile SMILES: CC1=CC(C)=C(C#N)C(Cl)=N1
| PubChem CID | 223261 |
|---|---|
| CAS | 14237-71-9 |
| Molecular Weight (g/mol) | 166.61 |
| MDL Number | MFCD00051676 |
| SMILES | CC1=CC(C)=C(C#N)C(Cl)=N1 |
| Synonym | 2-chloro-4,6-dimethylnicotinonitrile,2-chloro-3-cyano-4,6-dimethylpyridine,2-chloro-4,6-dimethyl-nicotinonitrile,2-chloro-4,6-dimethyl-3-pyridinecarbonitrile,3-pyridinecarbonitrile, 2-chloro-4,6-dimethyl,acmc-1azio,chlorodimethylnicotinonitrile,ksc496m6f,2-chloro-4,6-dimethyinicotinonitrile,4,6-dimethyl-2-chloro-nicotinonitrile |
| IUPAC Name | 2-chloro-4,6-dimethylpyridine-3-carbonitrile |
| InChI Key | RETJKTAVEQPNMH-UHFFFAOYSA-N |
| Molecular Formula | C8H7ClN2 |
1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one 98.0+%, TCI America™
CAS: 6969-71-7 Molecular Formula: C6H5N3O Molecular Weight (g/mol): 135.126 MDL Number: MFCD00022632 InChI Key: LJRXNXBFJXXRNQ-UHFFFAOYSA-N Synonym: 1,2,4-triazolo 4,3-a pyridin-3 2h-one,1,2,4 triazolo 4,3-a pyridin-3 2h-one,2h-1,2,4 triazolo 4,3-a pyridin-3-one,1,2,4 triazolo 4,3-a pyridin-3-ol,s-triazolo 4,3-a pyridin-3-ol,2h,3h-1,2,4 triazolo 4,3-a pyridin-3-one,3-hydroxytriazolo 4,3-a pyridine,1,2,4-triazolo-4,3,a pyridin-3 2h-one,4-hydro-2h-1,2,4-triazolino 4,3-a pyridin-3-one PubChem CID: 81431 IUPAC Name: 2H-[1,2,4]triazolo[4,3-a]pyridin-3-one SMILES: C1=CC2=NNC(=O)N2C=C1
| PubChem CID | 81431 |
|---|---|
| CAS | 6969-71-7 |
| Molecular Weight (g/mol) | 135.126 |
| MDL Number | MFCD00022632 |
| SMILES | C1=CC2=NNC(=O)N2C=C1 |
| Synonym | 1,2,4-triazolo 4,3-a pyridin-3 2h-one,1,2,4 triazolo 4,3-a pyridin-3 2h-one,2h-1,2,4 triazolo 4,3-a pyridin-3-one,1,2,4 triazolo 4,3-a pyridin-3-ol,s-triazolo 4,3-a pyridin-3-ol,2h,3h-1,2,4 triazolo 4,3-a pyridin-3-one,3-hydroxytriazolo 4,3-a pyridine,1,2,4-triazolo-4,3,a pyridin-3 2h-one,4-hydro-2h-1,2,4-triazolino 4,3-a pyridin-3-one |
| IUPAC Name | 2H-[1,2,4]triazolo[4,3-a]pyridin-3-one |
| InChI Key | LJRXNXBFJXXRNQ-UHFFFAOYSA-N |
| Molecular Formula | C6H5N3O |
Medchemexpress LLC Lobendazole 50mg | 50MG
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Lobendazole 50mg | 50MG
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Medchemexpress LLC (R)-lunresertib ((R)-RP-6306) | 2719793-91-4 | 99.9% | C18H20N4O2 | 1 ML
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(R)-lunresertib is an inhibitor of membrane-associated tyrosine and threonine-specific cdc2-inhibitory kinase (Myt1), also known by the gene name PKMYT1. It has an IC50 of 1360 nM and is utilized in the study of Myt1-mediated cancers. This product is an off-white to gray solid.
- Inhibits Myt1 (PKMYT1) with an IC50 of 1360 nM
- Used for research into Myt1-mediated cancers
- Appears as an off-white to gray solid
- Soluble in DMSO at 100 mg/mL
- For research use only, not for patient use
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Apexbio Technology LLC DAMGO 78123-71-4 10mg
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DAMGO (CAS 78123-71-4) is a peptide agonist selective for the -opioid receptor showing high affinity with a Ki of approximately 1 18 nM compared to markedly lower affinities for - and -opioid receptors -opioid receptors are class A G protein-coupled receptors that transduce signals via intracellular G protein cascades and regulate multiple cellular processes commonly studied for their role in pain pathways DAMGO activates -opioid signaling as demonstrated by increased [ 35S]GTP S binding in cell membrane assays (EC50 222 nM) inhibition of muscle contractions in mouse vas deferens (EC50 238 47 nM) and reduction of visceral pain responses in rat models Therefore DAMGO serves as an important research tool for investigating -opioid receptor biology and analgesia
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Apexbio Technology LLC DAMGO 78123-71-4 25mg
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DAMGO (CAS 78123-71-4) is a peptide agonist selective for the -opioid receptor showing high affinity with a Ki of approximately 1 18 nM compared to markedly lower affinities for - and -opioid receptors -opioid receptors are class A G protein-coupled receptors that transduce signals via intracellular G protein cascades and regulate multiple cellular processes commonly studied for their role in pain pathways DAMGO activates -opioid signaling as demonstrated by increased [ 35S]GTP S binding in cell membrane assays (EC50 222 nM) inhibition of muscle contractions in mouse vas deferens (EC50 238 47 nM) and reduction of visceral pain responses in rat models Therefore DAMGO serves as an important research tool for investigating -opioid receptor biology and analgesia
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Apexbio Technology LLC XL-888 1149705-71-4 10mg
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XL-888 (CAS 1149705-71-4) is an orally bioavailable small molecule inhibitor targeting heat shock protein 90 (HSP90) It selectively inhibits HSP90 and HSP90 with IC50 values of 22 nM and 44 nM respectively while exhibiting markedly weaker inhibition against a panel of other kinases Structural analyses indicated XL-888 binds HSP90 via hydrogen bonding interactions involving the Asp93 residue In tumor cell assays XL-888 potently suppresses proliferation with IC50 values in the range of 0 1-45 5 nM XL-888 is used in oncology research particularly for studying resistance mechanisms to targeted therapies
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Apexbio Technology LLC XL-888 1149705-71-4 25mg
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XL-888 (CAS 1149705-71-4) is an orally bioavailable small molecule inhibitor targeting heat shock protein 90 (HSP90) It selectively inhibits HSP90 and HSP90 with IC50 values of 22 nM and 44 nM respectively while exhibiting markedly weaker inhibition against a panel of other kinases Structural analyses indicated XL-888 binds HSP90 via hydrogen bonding interactions involving the Asp93 residue In tumor cell assays XL-888 potently suppresses proliferation with IC50 values in the range of 0 1-45 5 nM XL-888 is used in oncology research particularly for studying resistance mechanisms to targeted therapies
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