Pyridines and derivatives
2-Fluoro-3-nitropyridine 98.0+%, TCI America™
CAS: 1480-87-1 Molecular Formula: C5H3FN2O2 Molecular Weight (g/mol): 142.09 MDL Number: MFCD03095068 InChI Key: QDKIYDGHCFZBGC-UHFFFAOYSA-N Synonym: 2-fluoro-3-nitro-pyridine,pyridine, 2-fluoro-3-nitro,pubchem1115,acmc-1bwlp,2-fluor-3-nitropyridine,2-fluoro-3-nitropyridine,ksc174g2n PubChem CID: 2762817 IUPAC Name: 2-fluoro-3-nitropyridine SMILES: [O-][N+](=O)C1=C(F)N=CC=C1
2-Methyl-3-nitropyridine 98.0+%, TCI America™
CAS: 18699-87-1 Molecular Formula: C6H6N2O2 Molecular Weight (g/mol): 138.13 MDL Number: MFCD04114137 InChI Key: CCFGTKQIRWHYTB-UHFFFAOYSA-N Synonym: 2-methyl-3-nitro-pyridine,3-nitro-2-picoline,3-nitropicoline,3-nitro-2-methylpyridine,pyridine, 2-methylnitro,pyridine, 2-methyl-3-nitro-9ci,nitropicoline,zlchem 137,acmc-209ep0,pyridine, 2-methyl-3-nitro PubChem CID: 329360 IUPAC Name: 2-methyl-3-nitropyridine SMILES: CC1=NC=CC=C1[N+]([O-])=O
4-Chloro-N-methyl-2-pyridinecarboxamide 98.0+%, TCI America™
CAS: 220000-87-3 Molecular Formula: C7H7ClN2O Molecular Weight (g/mol): 170.60 MDL Number: MFCD02185921 InChI Key: BGVBBMZMEKXUTR-UHFFFAOYSA-N Synonym: 4-chloro-n-methylpicolinamide,n-methyl-4-chloropyridine-2-carboxamide,4-chloro-n-methyl-2-pyridinecarboxamide,n-methyl 4-chloropicolinamide,2-pyridinecarboxamide, 4-chloro-n-methyl,4-chloropyridine-2-carboxylic acid methylamide,4-chloro-n-methyl-pyridine-2-carboxamide,n-methyl-4-chloro-2-pyridinamide,4-chloro 2-pyridyl-n-methylcarboxamide,4-chloranyl-∼ n-methyl-pyridine-2-carboxamide PubChem CID: 1476814 IUPAC Name: 4-chloro-N-methylpyridine-2-carboxamide SMILES: CNC(=O)C1=NC=CC(Cl)=C1
![4-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyridine 98.0+%, TCI America™](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-1009033-87-7.jpg-250.jpg)
4-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyridine 98.0+%, TCI America™
CAS: 1009033-87-7 Molecular Formula: C17H20BNO2 Molecular Weight (g/mol): 281.162 MDL Number: MFCD12828171 InChI Key: PTNMCYWJKRZCDE-UHFFFAOYSA-N Synonym: 4,4,5,5-Tetramethyl-2-[4-(4-pyridyl)phenyl]-1,3,2-dioxaborolane, 4-(4-Pyridyl)phenylboronic Acid Pinacol Ester PubChem CID: 58526497 IUPAC Name: 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyridine SMILES: B1(OC(C(O1)(C)C)(C)C)C2=CC=C(C=C2)C3=CC=NC=C3
Apexbio Technology LLC Gestodene 60282-87-3 50mg
Gestodene (60282-87-3) is a small-molecule agonist targeting progesterone receptors It is designed to modulate the hypothalamic-pituitary-gonadal axis thereby regulating hormonal secretion and ovulatory processes Gestodene exerts its biological activity primarily through high-affinity binding and agonist activity on progesterone receptors leading to suppression of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion inhibition of ovulation alteration of cervical mucus viscosity and modification of endometrial morphology Based on these pharmacological properties Gestodene holds research potential in reproductive biology endocrinology and contraceptive mechanism studies
Apexbio Technology LLC Gestodene 60282-87-3 10mg
Gestodene (60282-87-3) is a small-molecule agonist targeting progesterone receptors It is designed to modulate the hypothalamic-pituitary-gonadal axis thereby regulating hormonal secretion and ovulatory processes Gestodene exerts its biological activity primarily through high-affinity binding and agonist activity on progesterone receptors leading to suppression of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion inhibition of ovulation alteration of cervical mucus viscosity and modification of endometrial morphology Based on these pharmacological properties Gestodene holds research potential in reproductive biology endocrinology and contraceptive mechanism studies
Apexbio Technology LLC Gestodene 60282-87-3 25mg
Gestodene (60282-87-3) is a small-molecule agonist targeting progesterone receptors It is designed to modulate the hypothalamic-pituitary-gonadal axis thereby regulating hormonal secretion and ovulatory processes Gestodene exerts its biological activity primarily through high-affinity binding and agonist activity on progesterone receptors leading to suppression of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion inhibition of ovulation alteration of cervical mucus viscosity and modification of endometrial morphology Based on these pharmacological properties Gestodene holds research potential in reproductive biology endocrinology and contraceptive mechanism studies
Apexbio Technology LLC Nanchangmycin 65101-87-3 10mg
Nanchangmycin (65101-87-3) is a polyether ionophore antibiotic designed to facilitate the transport of monovalent cations across lipid bilayers thereby disrupting ion transport mechanisms in cellular membranes Nanchangmycin exerts its biological activity primarily through acting as an ionophore that compromises cellular ionic gradients In in vitro studies using nematode and insect models Nanchangmycin demonstrates potent inhibitory activity on nematode growth and development with reported IC50 values ranging from low nanomolar to micromolar concentrations depending on species and assay conditions Based on these pharmacological properties Nanchangmycin holds research potential in studies of membrane function ion transport mechanisms host-pathogen interactions and pesticide target validation
Apexbio Technology LLC Gestodene 60282-87-3 100mg
Gestodene (60282-87-3) is a small-molecule agonist targeting progesterone receptors It is designed to modulate the hypothalamic-pituitary-gonadal axis thereby regulating hormonal secretion and ovulatory processes Gestodene exerts its biological activity primarily through high-affinity binding and agonist activity on progesterone receptors leading to suppression of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion inhibition of ovulation alteration of cervical mucus viscosity and modification of endometrial morphology Based on these pharmacological properties Gestodene holds research potential in reproductive biology endocrinology and contraceptive mechanism studies
Apexbio Technology LLC Nanchangmycin 65101-87-3 5mg
Nanchangmycin (65101-87-3) is a polyether ionophore antibiotic designed to facilitate the transport of monovalent cations across lipid bilayers thereby disrupting ion transport mechanisms in cellular membranes Nanchangmycin exerts its biological activity primarily through acting as an ionophore that compromises cellular ionic gradients In in vitro studies using nematode and insect models Nanchangmycin demonstrates potent inhibitory activity on nematode growth and development with reported IC50 values ranging from low nanomolar to micromolar concentrations depending on species and assay conditions Based on these pharmacological properties Nanchangmycin holds research potential in studies of membrane function ion transport mechanisms host-pathogen interactions and pesticide target validation
Apexbio Technology LLC Nanchangmycin 65101-87-3 50mg
Nanchangmycin (65101-87-3) is a polyether ionophore antibiotic designed to facilitate the transport of monovalent cations across lipid bilayers thereby disrupting ion transport mechanisms in cellular membranes Nanchangmycin exerts its biological activity primarily through acting as an ionophore that compromises cellular ionic gradients In in vitro studies using nematode and insect models Nanchangmycin demonstrates potent inhibitory activity on nematode growth and development with reported IC50 values ranging from low nanomolar to micromolar concentrations depending on species and assay conditions Based on these pharmacological properties Nanchangmycin holds research potential in studies of membrane function ion transport mechanisms host-pathogen interactions and pesticide target validation
Apexbio Technology LLC SLx-2119 911417-87-3 25mg
SLx-2119 (CAS 911417-87-3) also known as KD-025 is a selective inhibitor targeting Rho-associated protein kinase 2 (ROCK2) exhibiting an IC50 of approximately 105 nM ROCK2 is a serine/threonine kinase central to cytoskeletal modulation and cellular signaling particularly expressed within neuronal and vascular cells SLx-2119 reduces connective tissue growth factor (CTGF) mRNA expression selectively in human intestinal smooth muscle cells isolated from radiation-induced fibrosis tissue (RE-SMC) whereas normal smooth muscle cells remain unaffected Additionally in a murine model of focal cerebral ischemia SLx-2119 treatment yields a dose-dependent decrease in infarct size across aged and diabetic models highlighting its research applicability in ischemic stroke and fibrotic disorders
Apexbio Technology LLC SLx-2119 911417-87-3 5mg
SLx-2119 (CAS 911417-87-3) also known as KD-025 is a selective inhibitor targeting Rho-associated protein kinase 2 (ROCK2) exhibiting an IC50 of approximately 105 nM ROCK2 is a serine/threonine kinase central to cytoskeletal modulation and cellular signaling particularly expressed within neuronal and vascular cells SLx-2119 reduces connective tissue growth factor (CTGF) mRNA expression selectively in human intestinal smooth muscle cells isolated from radiation-induced fibrosis tissue (RE-SMC) whereas normal smooth muscle cells remain unaffected Additionally in a murine model of focal cerebral ischemia SLx-2119 treatment yields a dose-dependent decrease in infarct size across aged and diabetic models highlighting its research applicability in ischemic stroke and fibrotic disorders
Medchemexpress LLC Zim | 301298-87-3 | C20H19N3O3 | 25 MG
Zim is a norbornene derived from 4-aminoantipyrine, functioning as a potent inducer of DNA damage. It causes genomic and chromosomal damage, triggers cell death, and activates phagocytosis, indicating its chemotherapeutic potential for cancer research.
- Potent inducer of DNA damage
- Causes genomic and chromosomal damage
- Induces cell death
- Activates phagocytosis
- Shows chemotherapeutic potential for cancer research
- Reduces the frequency of chromosome micronucleus
- Reduces cisplatin and doxorubicin-induced liver and kidney cell death