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Filtered Search Results
Apexbio Technology LLC 2-4 Dihydroxypyrimidine-5-CA
2 4-Dihydroxypyrimidine-5-carboxylic Acid (CAS No 23945-44-0) is a compound frequently utilized in biomedical research due to its potential therapeutic applications Originating as a pyrimidine derivative it primarily interacts with nucleic acid pathways influencing various cellular processes Its mechanism of action makes it a candidate for studies targeting nucleotide biosynthesis and related metabolic pathways In vitro activity often falls within a nanomolar to low micromolar range indicating its potency at low concentrations Typical applications include cell models and animal studies where it aids in drug screening and the exploration of cellular responses Experimental concentrations typically depend on the specific research design allowing for tailored investigations into distinct biological questions This compound s versatility underscores its value in advancing therapeutic research and development
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Selleck Chemical LLC KDM4D-IN-1 S1059-2mg
KDM4D-IN-1 is a potent inhibitor of KDM4D with an IC50 of 0 41 M
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Cn1cnc2c(O)nc(N)nc12)OCC | 1g | 499993732](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502167858.JPG-250.jpg)
eMolecules 1369530-26-6 | S-guanine alcohol | Synthonix - Stock | MFCD28386248 | 325.369 | C14H23N5O4 | 95.000 | CCOC(C[C@H](CO)Cn1cnc2c(O)nc(N)nc12)OCC | 1g | 499993732
S-guanine alcohol | Synthonix - Stock | 1369530-26-6 | MFCD28386248 | 325.369 | C14H23N5O4 | 95.000 | CCOC(C[C@H](CO)Cn1cnc2c(O)nc(N)nc12)OCC | 1g | 499993732
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![eMolecules 1143525-19-2 | Guanosine hydrate | J & W PharmLab LLC | MFCD00149584 | 301.259 | C10H15N5O6 | 96.000 | O.Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O | 1g | 517669157](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502147604.JPG-250.jpg)
eMolecules 1143525-19-2 | Guanosine hydrate | J & W PharmLab LLC | MFCD00149584 | 301.259 | C10H15N5O6 | 96.000 | O.Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O | 1g | 517669157
Guanosine hydrate | J & W PharmLab LLC | 1143525-19-2 | MFCD00149584 | 301.259 | C10H15N5O6 | 96.000 | O.Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O | 1g | 517669157
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Medchemexpress LLC HY-W040055 10mg Medchemexpress, Neopterin CAS:2009-64-5 Purity:>98%
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Medchemexpress, HY-W040055 10mg Neopterin CAS:2009-64-5 Neopterin (D-(+)-Neopterin), a catabolic product of guanosine triphosphate (GTM), serves as a marker of cellular immune system activation. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Accela Chembio Inc 4 | 6-dihydroxy-2-methylpyrimidine | 100g | 40497-30-1 | MFCD00006104 | 97+% | Shelf Life: 1620 Days | Regular
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4 | 6-dihydroxy-2-methylpyrimidine | 100g | 40497-30-1 | MFCD00006104 | 97+% | Shelf Life: 1620 Days | Regular
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Aobchem AOBCHEM
5001082194 2- TERT-BUTYLTHIO PYRIMIDIN-5
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![Aobchem 1-Benzo[b]thien-5-ylethanone | ≥95% | CAS 1128-88-7 | C10H8OS | 500mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000974847.png-250.jpg)
Aobchem 1-Benzo[b]thien-5-ylethanone | ≥95% | CAS 1128-88-7 | C10H8OS | 500mg
1-Benzo[b]thien-5-ylethanone | ≥95% | CAS 1128-88-7 | C10H8OS | 500mg
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Aobchem 5-Bromo-2-(ethylthio)pyrimidine | ≥95% | CAS 859941-10-9 | C6H7BrN2S | 5g
5-Bromo-2-(ethylthio)pyrimidine | ≥95% | CAS 859941-10-9 | C6H7BrN2S | 5g
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![eMolecules 271-70-5 | 7H-pyrrolo[2,3-d]pyrimidine | Pharmablock | MFCD08234403 | 119.127 | C6H5N3 | 97.000 | c1cc2cncnc2[nH]1 | 50g | 551054101](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000188165.jpg-250.jpg)
eMolecules 271-70-5 | 7H-pyrrolo[2,3-d]pyrimidine | Pharmablock | MFCD08234403 | 119.127 | C6H5N3 | 97.000 | c1cc2cncnc2[nH]1 | 50g | 551054101
7H-pyrrolo[2,3-d]pyrimidine | Pharmablock | 271-70-5 | MFCD08234403 | 119.127 | C6H5N3 | 97.000 | c1cc2cncnc2[nH]1 | 50g | 551054101
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Medchemexpress LLC HY-108335 5mg Medchemexpress, Sipatrigine CAS:130800-90-7 Purity:>98%
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Medchemexpress, HY-108335 5mg Sipatrigine CAS:130800-90-7 Sipatrigine, a neuroprotective agent, is a glutamate release inhibitor, voltage-dependent sodium channel and calcium channel inhibitor, penetrating the central nervous system. Has potential to treat focal cerebral ischemia and stroke [1] [2] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Aobchem AOBCHEM
5000944924 1- 2- DIMETHYLAMINO PYRIMIDIN-
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![Medchemexpress LLC N-[4-[6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl]oxy-1,3-benzothiazol-2-yl]acetamide | 659730-32-2 | MFCD14584859 | 99.2% | 430.40 | C20H13F3N4O2S | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000244040.png-250.jpg)
Medchemexpress LLC N-[4-[6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl]oxy-1,3-benzothiazol-2-yl]acetamide | 659730-32-2 | MFCD14584859 | 99.2% | 430.40 | C20H13F3N4O2S | 25 MG
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AMG 517 is a potent, selective small-molecule antagonist of the vanilloid receptor TRPV1 for research use. It inhibits TRPV1-mediated calcium influx in cell-based and neuronal assays with low-nanomolar IC50 values, and is supplied as a high-purity solid suitable for pharmacology and biochemical studies.
- High purity solid suitable for in vitro research.
- Low-nanomolar TRPV1 potency (IC50 ≈ 0.5-0.9 nM).
- Molecular weight 430.40, formula C20H13F3N4O2S.
- Supplied with data sheet, certificate of analysis, and safety data sheet.
- Soluble in DMSO for preparation of stock solutions.
- Available in multiple pack sizes for flexibility in study scale.
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![Medchemexpress LLC N-[4-(2-chloro-5-methylpyrimidin-4-yl)phenyl]-N-[(4-(difluoroacetylamino)methyl)phenyl]methyl-2,4-dihydroxybenzamide | 1684386-71-7 | 99.1% | 552.96 g/mol | C28H23ClF2N4O4 | 25MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000235093.png-250.jpg)
Medchemexpress LLC N-[4-(2-chloro-5-methylpyrimidin-4-yl)phenyl]-N-[(4-(difluoroacetylamino)methyl)phenyl]methyl-2,4-dihydroxybenzamide | 1684386-71-7 | 99.1% | 552.96 g/mol | C28H23ClF2N4O4 | 25MG
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VER-246608 is a potent, ATP-competitive inhibitor of pyruvate dehydrogenase kinase (PDK) isoforms, developed for biochemical and cell-based research. It shows sub-100 nM enzymatic potency across PDK isoforms and reduces E1α Ser293 phosphorylation in cellular assays. Supplied as a solid and as DMSO solutions for laboratory use.
- Potent ATP-competitive inhibition of pyruvate dehydrogenase kinase isoforms.
- IC50 values: PDK-1 35 nM; PDK-3 40 nM; PDK-2 84 nM; PDK-4 91 nM.
- Suppresses phosphorylation of E1α Ser293 in cellular assays (IC50 ≈ 266 nM).
- High purity: 99.1%.
- Molecular formula C28H23ClF2N4O4; molecular weight 552.96 g/mol.
- Available as solid (25 MG) and as 10 mM solutions in DMSO for convenience.
- Recommended storage: powder at -20°C or 4°C; in solvent store at -80°C for long-term stability.
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Medchemexpress LLC HY-103546 5mg Medchemexpress, BETP CAS:1371569-69-5 Purity:>98%
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Medchemexpress, HY-103546 5mg BETP CAS:1371569-69-5 BETP is an agonist of glucagon-like peptide-1 (GLP-1) receptor, with EC50s of 0.66 and 0.755 μM for human and rat GLP-1 receptor, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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