Pyrroles
Medchemexpress LLC TLR7 agonist 4 | 2413016-42-7 | 98.9% | C23H34N6O3 | 100 MG
TLR7 agonist 4 is a laboratory chemical used for research purposes.
- Recommended storage at 4°C, sealed, and away from moisture.
- For solvent storage, -80°C for 6 months or -20°C for 1 month, sealed, and away from moisture.
- Can be shipped at room temperature if less than 2 weeks.
- Suitable for laboratory research.
Cayman Chemical NhexanoylDLHomoserine lactone
A bacterial quorum sensing signaling molecule; produced by mammalian pathogenic and rhizosphere-colonizing bacteria; application to tomato leaves suppresses the development of lesions induced by the plant pathogenic fungi B. cinerea at 60 µM; increases root length and shoot diameter when applied to A. thaliana seedlings in a hydroponic growth system at 10 µM
Apexbio Technology LLC AHU-377 hemicalcium salt 1369773-39-6 50mg
AHU-377 hemicalcium salt (CAS 1369773-39-6) is a hemicalcium salt form of AHU-377 a potent inhibitor of neprilysin (neutral endopeptidase) with an IC50 of 5 nM As a prodrug AHU-377 is enzymatically converted to its active metabolite LBQ657 following ester cleavage AHU-377 is a key component of LCZ696 co-formulated with valsartan at a 1 1 molar ratio functioning as an angiotensin receptor neprilysin inhibitor (ARNI) In vivo studies demonstrate that oral administration of AHU-377 induces dose-dependent blood pressure reduction in DAHI-SS rats though it has less pronounced effects in DOCA-salt hypertensive models AHU-377 is widely studied in cardiovascular research particularly in the context of heart failure and hypertension
Medchemexpress LLC α-Angelica lactone | 591-12-8 | 98.10 | 500 MG
α-Angelica lactone is a naturally occurring anticarcinogen and a vinylogous nucleophile. It can produce chiral δ-amino γ,γ-disubstituted butenolide carbonyl derivatives and demonstrates electrophilic trapping at the γ-carbon. This compound exhibits strong chemoprotective effects by selectively enhancing glutathione-S-thansferase (GST) and UDP-glucononosyltransferase (UGT) detoxification enzymes.
- Naturally occurring anticarcinogen
- Exhibits strong chemoprotective effects
- Enhances glutathione-S-thansferase (GST) detoxification enzyme activity
- Enhances UDP-glucononosyltransferase (UGT) detoxification enzyme activity
eMolecules 1211578-75-4 | 3-BROMO-2-CHLORO-6-FLUOROPYRIDINE | AstaTech | MFCD18257575 | 210.430 | C5H2BrClFN | 95.000 | Fc1ccc(Br)c(Cl)n1 | 1g | 475589658
3-BROMO-2-CHLORO-6-FLUOROPYRIDINE | AstaTech | 1211578-75-4 | MFCD18257575 | 210.430 | C5H2BrClFN | 95.000 | Fc1ccc(Br)c(Cl)n1 | 1g | 475589658
Medchemexpress LLC Almotriptan (malate) | 181183-52-8 | 99.5% | 25 MG
Almotriptan malate is an orally active, highly selective 5-HT1B/1D-receptor agonist. It is utilized in research for treating migraine, inducing intracranial vasoconstriction, suppressing vasoactive peptides from trigeminal nerve endings, and inhibiting nociceptive neurotransmission in the trigeminocervical complex. This compound shows low nanomolar affinity for 5-HT1B and 5-HT1D receptors.
- Highly selective 5-HT1B/1D-receptor agonist
- Induces intracranial vasoconstriction
- Suppresses vasoactive peptide release
- Inhibits nociceptive neurotransmission
- Exhibits low nanomolar affinity for 5-HT1B and 5-HT1D receptors
- Has a mild antiemetic effect
- Shows a slight, transient diuretic effect