Pyrroles
Selleck Chemical LLC YM 90709
YM 90709 is a novel IL-5 inhibitor which selectively blocks the binding of IL-5 to the IL-5 receptor (IL-5R)
Medchemexpress LLC A-1210477 | 1668553-26-1 | MFCD28399118 | 99.9% | 850.04 g/mol | C46H55N7O7S | 25MG
A-1210477 is a potent, selective small-molecule inhibitor of the anti-apoptotic protein MCL-1 used as a research tool to study apoptosis and MCL-1-dependent cancer biology. It binds MCL-1 with sub-nanomolar affinity and disrupts MCL-1 protein-protein interactions to promote apoptosis in sensitive cell lines.
- Potent, selective MCL-1 inhibition with Ki ≈ 0.45 nM.
- Disrupts MCL-1 interactions to induce programmed cell death.
- Suitable for cell-based assays and mechanistic studies of apoptosis.
- High purity for reproducible experimental results.
- Solid powder formulation with recommended cold storage for stability.
Medchemexpress LLC Atorvastatin calcium salt trihydrate | 344423-98-9 | 99.8% | 605.71 | 1 G
Atorvastatin calcium salt trihydrate is a drug belonging to the statin class of drugs used to lower blood cholesterol levels. Atorvastatin calcium salt trihydrate has unique chemical properties that make it an effective tool in controlling high levels of low-density lipoprotein (LDL) cholesterol and triglycerides in the body, reducing the risk of heart attack and stroke. Atorvastatin calcium salt trihydrate works by inhibiting HMG-CoA reductase, the enzyme responsible for producing cholesterol in the liver.
- Lowers blood cholesterol levels.
- Controls high levels of low-density lipoprotein (LDL) cholesterol and triglycerides.
- Reduces the risk of heart attack and stroke.
- Works by inhibiting HMG-CoA reductase, the enzyme responsible for producing cholesterol in the liver.
- Can be used as a biochemical reagent for life science-related research.
eMolecules 393105-53-8 | Medchem Express | Tiplaxtinin | 5mg | 446265275 | HY-15253 | MFCD09475615 | 439.39 | C24H16F3NO4
ChemScene | 2-(2-Chloro-4-fluorophenyl)-4455-tetramethyl-132-dioxaborolane | 100mg | 714185624 | CS-0279218 | 892845-64-6 | MFCD18729910 | 256.510 | C12H15BClFO2
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
Medchemexpress LLC Quiflapon (MK-591) | 136668-42-3 | 99.4% | 587.17 g/mol | C34H35ClN2O3S | 10 MG
Quiflapon (MK-591) is a selective 5-lipoxygenase-activating protein (FLAP) inhibitor used to block leukotriene biosynthesis and study inflammatory signaling. It is provided as a high-purity research reagent in solid form and as a DMSO solution for biochemical and cellular assays.
- Selective FLAP inhibitor with low-nanomolar potency (IC50 ~1.6 nM).
- High purity, suitable for research applications.
- Available as small solid quantities and as a DMSO solution.
- Suitable for biochemical and cell-based assays.
- Molecular formula C34H35ClN2O3S; molecular weight 587.17 g/mol.
eMolecules 146204-42-4 | Medchem Express | BM212 | 5mg | 446255938 | HY-100725 | MFCD30489752 | 414.37 | C23H25Cl2N3
ChemScene | 444-Nitrilotris(([11-biphenyl]-35-dicarbaldehyde)) | 100mg | 598463212 | CS-0110961 | 2030105-85-0 | 641.679 | C42H27NO6
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
eMolecules 1197397-89-9 | Medchem Express | CBL0137 (hydrochloride) | 2mg | 446269504 | HY-18935A | MFCD28160457 | 372.89 | C21H25ClN2O2
ChemScene | 2-Fluoro-3-(hydroxymethyl)benzonitrile | 100mg | 632299493 | CS-0157232 | 1261861-91-9 | MFCD18394036 | 151.140 | C8H6FNO
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Medchemexpress LLC Kw-8232 methanesulfonate | 217813-15-5 | 98.1% | 705.26 g·mol⁻¹ | C37H41ClN4O6S | 100 MG
KW-8232 methanesulfonate is an orally active anti-osteoporotic small molecule that reduces prostaglandin E2 (PGE2) biosynthesis in osteoblastic cells and has been shown to inhibit bone loss in preclinical studies. It is supplied for research use in solid form and as a 10 mM solution in DMSO.
- Orally active anti-osteoporotic agent.
- Reduces prostaglandin E2 (PGE2) biosynthesis in osteoblastic cells.
- Demonstrated inhibition of bone loss in preclinical models.
- High purity (98.1%).
- Molecular weight 705.26 g·mol⁻¹; formula C37H41ClN4O6S.
- Available as solid and as a 10 mM solution in DMSO for in vitro and in vivo studies.
TARGETMOL CHEMICALS INC Atorvastatin hemicalcium salt
Also available in 1 mL, 10 mg, 25 mg, 50 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an HMG-CoA reductase inhibitor with oral activity. Atorvastatin hemicalcium salt is used to lower cholesterol. Purity 99.89%
Medchemexpress LLC Pyrrole-2-carboxylic acid | 634-97-9 | 111.10 | 25 G
Pyrrole-2-carboxylic acid is a natural alkaloid found in the marine bacterium *Pelomonas puraquae* sp. Nov. It is a biological form of pyrrole frequently encountered in natural compounds and acts as a precursor for various pyrrole derivatives in biosynthetic processes, including clorobiocin, coumermycin A1, pyoluteorin, leupyrrins, and undecylprodigiosin.
- Natural alkaloid sourced from marine bacterium *Pelomonas puraquae* sp. Nov.
- Acts as a precursor for various pyrrole derivatives.
- Exhibits antineuroinflammatory activity in LPS-induced mouse BV-2 cells.
Apexbio Technology LLC Bromoenol lactone 88070-98-8 5mg
Bromoenol lactone (CAS 88070-98-8) is an irreversible inhibitor of cytosolic calcium-independent phospholipase A2 (iPLA2) an enzyme involved in the regulation of arachidonic acid release and lysophospholipid production iPLA2 activity is associated with phospholipid remodeling and the generation of signaling molecules that modulate processes such as eicosanoid synthesis insulin secretion apoptosis and cellular proliferation In cellular assays bromoenol lactone induces apoptosis in various cell lines and promotes proteolysis of procaspase-9 and procaspase-3 It also inhibits phosphatidic acid phosphohydrolase activity and disrupts triacylglycerol biosynthesis in macrophage models Bromoenol lactone is widely utilized in studies investigating lipid signaling cell death mechanisms and metabolic pathways
Cayman Chemical NdecanoylLHomoserine lactone
A small diffusible signaling molecule involved in quorum sensing, controlling gene expression, and affecting cellular metabolism; applications for this molecule include regulation of virulence and exoproteases
eMolecules (S)-2-N-BOC-AMINO-1-PYRROLIDIN-1-YL-PROPAN-1-ONE | 138356-92-0 | MFCD09025328 | 1g
AstaTech | (S)-2-N-BOC-AMINO-1-PYRROLIDIN-1-YL-PROPAN-1-ONE | 1g | 112523971 | 55920 | 97.000 | 138356-92-0 | MFCD09025328 | 242.319 | C12H22N2O3
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Medchemexpress LLC 3-Morpholinecarboxamide, N-[4-[[5-(1,6-dimethyl-1H-pyrazolo[3,4-b]pyridin-4-yl)-... | 2205095-75-4 | 99.9% | 532.68 g/mol | C29H40N8O2 | 5 MG
TLR7/8-IN-1 is a crystalline form of a dual TLR7/TLR8 inhibitor (patent WO2019220390, compound 2b) provided for laboratory research, including studies of autoimmune disease. The compound is supplied as a white to off-white solid or as DMSO solutions, and is characterized by defined molecular and purity data for reproducible preclinical use.
- High purity: 99.92%.
- Molecular weight: 532.68 g/mol.
- Chemical formula: C29H40N8O2.
- Soluble in DMSO (12.5 mg/mL; ultrasonic recommended).
- Available as milligram quantities or 10 mM DMSO solutions for experimental use.
- Storage stability: powder -20 °C (3 years); in solvent -80 °C (6 months).