Pyrroles
Medchemexpress LLC Atorvastatin hemicalcium | 134523-03-8 | 99.94% | 577.67 | 1 ML
Atorvastatin hemicalcium salt (CI-981) is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. It is capable of penetrating the blood-brain barrier and effectively reduces blood lipids. This compound inhibits human SV-SMC proliferation and invasion, and decreases apoptosis of myocardial cells by down-regulating specific proteins. It also activates endoplasmic reticulum (ER) stress in response to heart failure and angiotensin II (Ang II) stimulation. This product is for research use only.
- Orally active HMG-CoA reductase inhibitor
- Penetrates the blood-brain barrier
- Effectively reduces blood lipids
- Inhibits human SV-SMC proliferation and invasion
- Decreases myocardial cell apoptosis
- Activates endoplasmic reticulum (ER) stress response
- Reduces ER stress signaling proteins
- Inhibits proinflammatory cytokines
Medchemexpress LLC Atorvastatin hemicalcium salt | 134523-03-8 | 99.9% | 577.67 | 200 MG
Atorvastatin hemicalcium salt (CI-981) is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, with blood-brain barrier permeability. It has the ability to effectively decrease blood lipids. This compound inhibits human SV-SMC proliferation and invasion with IC50s of 0.39 μM and 2.39 μM, respectively.
- Orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor.
- Possesses blood-brain barrier permeability.
- Effectively decreases blood lipids.
- Inhibits human SV-SMC proliferation and invasion.
![Medchemexpress LLC Urea, N-[4-(1-amino-5-isoquinolinyl)phenyl]-N'-[5-(1,1-dimethylethyl)-3-isoxazolyl]- | 1481641-08-0 | 98.9% | 401.46 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000385494-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Urea, N-[4-(1-amino-5-isoquinolinyl)phenyl]-N'-[5-(1,1-dimethylethyl)-3-isoxazolyl]- | 1481641-08-0 | 98.9% | 401.46 | 50 MG
RIPK1-IN-4 is a potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase. It binds to a DLG-out inactive form of RIP1 with IC50s of 16 nM for RIP1 and 10 nM for ADP-Glo kinase.
- Potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase.
- Binds to a DLG-out inactive form of RIP1.
- For research use only.
Medchemexpress LLC Ethyl 2-amino-4-methyl-5-((3-nitrophenyl)carbamoyl)-thiophene-3-carboxylate | 303141-21-1 | 99.7% | 5 MG
DC-S239 is a small-molecule SET7 (SETD7) histone methyltransferase inhibitor used in epigenetics and cancer cell proliferation research.
- Selective SET7 inhibitor with reported IC50 = 4.59 μM.
- Anticancer activity; inhibits proliferation of MCF7, HL60, and MV4-11 cells.
- Molecular formula C15H15N3O5S; molecular weight 349.36 g/mol.
- Purity 99.7% as supplied.
- Solid, yellow to orange powder; store powder at -20°C for long term.
- Available in small research packs including 5 MG.
Medchemexpress LLC N-Boc-biocytin | 62062-43-5 | MFCD00133628 | >97.0% | 472.60 g/mol | C21H36N4O6S | 50 MG
N-Boc-Biocytin is a Boc-protected biotin PEG linker bearing a terminal carboxylic acid; it enables conjugation to primary amines through stable amide bond formation. The Boc group protects the amine during synthesis and can be cleaved under acidic conditions to reveal a free amine for subsequent derivatization. This reagent is intended for research use in peptide synthesis and bioconjugation workflows where a protected biotin handle is required.
- Boc-protected amine for controlled deprotection
- Terminal carboxylic acid for stable amide bond formation with primary amines
- Biotin functionality for affinity tagging and detection
- PEG spacer improves solubility and reduces steric hindrance
- Suitable for peptide synthesis and bioconjugation applications
Medchemexpress LLC Atorvastatin sodium | 134523-01-6 | MFCD08458204 | 99.9% | 580.6 g/mol | C33H34FN2NaO5 | 5 MG
Atorvastatin sodium is the sodium salt form of atorvastatin, an orally active HMG-CoA reductase inhibitor used in research to study lipid-lowering and related biological effects. Supplied as a solid or DMSO solution, it is suitable for in vitro and in vivo studies that require a well-characterized, high-purity HMG-CoA reductase inhibitor.
- Sodium salt form of atorvastatin
- Orally active HMG-CoA reductase inhibitor used in lipid-lowering research
- High reported purity (~99.9%) for consistent experimental results
- Available as solid and as DMSO solution formats for dosing flexibility
- Characterized with CAS 134523-01-6 and molecular weight 580.6 g/mol