Pyrroles
Medchemexpress LLC Almotriptan (malate) | 181183-52-8 | 99.5% | 25 MG
Almotriptan malate is an orally active, highly selective 5-HT1B/1D-receptor agonist. It is utilized in research for treating migraine, inducing intracranial vasoconstriction, suppressing vasoactive peptides from trigeminal nerve endings, and inhibiting nociceptive neurotransmission in the trigeminocervical complex. This compound shows low nanomolar affinity for 5-HT1B and 5-HT1D receptors.
- Highly selective 5-HT1B/1D-receptor agonist
- Induces intracranial vasoconstriction
- Suppresses vasoactive peptide release
- Inhibits nociceptive neurotransmission
- Exhibits low nanomolar affinity for 5-HT1B and 5-HT1D receptors
- Has a mild antiemetic effect
- Shows a slight, transient diuretic effect
![Aobchem 1-(4-Iodophenyl)tricyclo[3 3 1 13 7]decane | ≥95% | CAS 98611-00-8 | C16H19I | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000901709.png-250.jpg)
Aobchem 1-(4-Iodophenyl)tricyclo[3 3 1 13 7]decane | ≥95% | CAS 98611-00-8 | C16H19I | 1g
1-(4-Iodophenyl)tricyclo[3 3 1 13 7]decane | ≥95% | CAS 98611-00-8 | C16H19I | 1g
Medchemexpress LLC Pyrrole-2-carboxylic acid | 634-97-9 | 111.10 | 25 G
Pyrrole-2-carboxylic acid is a natural alkaloid found in the marine bacterium *Pelomonas puraquae* sp. Nov. It is a biological form of pyrrole frequently encountered in natural compounds and acts as a precursor for various pyrrole derivatives in biosynthetic processes, including clorobiocin, coumermycin A1, pyoluteorin, leupyrrins, and undecylprodigiosin.
- Natural alkaloid sourced from marine bacterium *Pelomonas puraquae* sp. Nov.
- Acts as a precursor for various pyrrole derivatives.
- Exhibits antineuroinflammatory activity in LPS-induced mouse BV-2 cells.
Medchemexpress LLC Ramosetron Hydrochloride | 132907-72-3 | 99.95% | 100 MG
Ramosetron Hydrochloride (YM060) is an orally active 5-HT3 antagonist. It is promising for research into irritable bowel syndrome with diarrhea, improving dysphoria, interference with activity, and food avoidance. It ameliorates 5-fluorouracil (5-FU)-induced intestinal mucositis in C57BL/6 mice.
- Orally active 5-HT3 antagonist
- Improves dysphoria and food avoidance
- Promising for irritable bowel syndrome with diarrhea research
- Ameliorates 5-FU-induced intestinal mucositis
- Targets the 5-HT3 receptor
Medchemexpress LLC 3-(cyclopropylmethyl)-7-((4-phenylpiperidin-1-yl)methyl)-8-(trifluoromethyl)-triazolopyridine | 1254980-38-5 | 98.8% | 5 MG
JNJ-46281222 is an mGlu2-selective positive allosteric modulator used as a research tool in receptor binding and functional assays; it has nanomolar affinity and is supplied as a high-purity solid or DMSO solution for in vitro studies.
- Metabotropic glutamate receptor 2 (mGlu2)-selective positive allosteric modulator
- High affinity: Kd = 1.7 nM
- Functional potency: pEC50 = 7.71 (EC50 ≈ 19-21 nM in CHO assays)
- Molecular formula C23H25F3N4; molecular weight 414.47 g·mol-1
- High purity (98.77%)
- Available as solid powder and as 10 mM solution in DMSO
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months)
- For research use only; not for human or clinical use
Aobchem 2-(2-Fluoro-3-iodophenyl)-1 3-dioxolane | 97% | CAS 2846109-52-0 | C9H8FIO2 | 250mg
2-(2-Fluoro-3-iodophenyl)-1 3-dioxolane | 97% | CAS 2846109-52-0 | C9H8FIO2 | 250mg
Aobchem 1-(2 6-Difluoro-3-iodophenyl)-2 2-dimethylpropan-1-ol | 97% | CAS 2921848-23-7 | C11H13F2IO | 1g
1-(2 6-Difluoro-3-iodophenyl)-2 2-dimethylpropan-1-ol | 97% | CAS 2921848-23-7 | C11H13F2IO | 1g
Aobchem 1-(2-Fluoro-5-iodophenyl)cyclopentanol | 97% | CAS 2918904-57-9 | C11H12FIO | 500mg
1-(2-Fluoro-5-iodophenyl)cyclopentanol | 97% | CAS 2918904-57-9 | C11H12FIO | 500mg
Aobchem 2-(2-Fluoro-4-iodophenyl)-1 3-dioxolane | 97% | C9H8FIO2 | 500mg
2-(2-Fluoro-4-iodophenyl)-1 3-dioxolane | 97% | C9H8FIO2 | 500mg
Aobchem 1-(3-Iodophenyl)-2-methyl-1-propanone | 97% | CAS 1595863-51-6 | C10H11IO | 250mg
1-(3-Iodophenyl)-2-methyl-1-propanone | 97% | CAS 1595863-51-6 | C10H11IO | 250mg
Aobchem 2-(2 5-Dimethyl-1H-pyrrol-1-yl)-5-(4 4 5 5-tetramethyl-1 3 2-dioxaborolan-2-yl)pyridine | ≥97% | CAS 885226-07-3 | C17H23BN2O2 | 250mg
2-(2 5-Dimethyl-1H-pyrrol-1-yl)-5-(4 4 5 5-tetramethyl-1 3 2-dioxaborolan-2-yl)pyridine | ≥97% | CAS 885226-07-3 | C17H23BN2O2 | 250mg