Pyrroles
Medchemexpress LLC Atorvastatin epoxy tetrahydrofuran impurity | 873950-19-7 | 449.47 | 50 MG
Atorvastatin epoxy tetrahydrofuran impurity is an impurity isolated from the oxidative degradation products of atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor that effectively decreases blood lipids. This product is for research use only and not sold to patients.
- Isolated from oxidative degradation products of atorvastatin.
- Atorvastatin is an orally active HMG-CoA reductase inhibitor.
- Effectively decreases blood lipids.
- Reduces apoptosis of myocardial cells by down-regulating GRP78, caspase-12, and CHOP expression after myocardial infarction.
- Involved in activation of endoplasmic reticulum (ER) stress in response to heart failure and angiotensin II (Ang II) stimulation.
Medchemexpress LLC Atorvastatin epoxy tetrahydrofuran impurity | 873950-19-7 | 449.47 | 25 MG
Atorvastatin Epoxy Tetrahydrofuran Impurity is an impurity isolated oxidative degradation product of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, which has the ability to effectively decrease blood lipids. Atorvastatin treatment decreases apoptosis of myocardial cells by down-regulating GRP78, caspase-12 and CHOP expression in myocardial cells after myocardial infarction. The endoplasmic reticulum (ER) stress is activated in response to heart failure and angiotensin II (Ang II) stimulation.
- Impurity isolated oxidative degradation product
- Orally active HMG-CoA reductase inhibitor
- Effectively decreases blood lipids
- Decreases apoptosis of myocardial cells
- Down-regulates GRP78, caspase-12 and CHOP expression
Medchemexpress LLC Atorvastatin epoxy tetrahydrofuran impurity | 873950-19-7 | 449.47 | 100 MG
Atorvastatin epoxy tetrahydrofuran impurity is an oxidative degradation product of atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor known for effectively decreasing blood lipids. This product is intended for research use only.
- Impurity of atorvastatin
- Isolated oxidative degradation product
- For research use only
Medchemexpress LLC Atorvastatin epoxy tetrahydrofuran impurity | 873950-19-7 | MFCD31700699 | 96.0% | C26H24FNO5 | 10MG
Atorvastatin epoxy tetrahydrofuran impurity is an oxidative degradation product of atorvastatin provided as an analytical reference standard for research use. Supplied in milligram quantities, it supports impurity profiling, method development, and stability testing. Users should consult the lot-specific Certificate of Analysis for purity and storage conditions.
- Used as an impurity reference for analytical method development.
- Suitable for stability studies and degradation profiling.
- Provided in small, laboratory-scale quantities for research use.
- Chemical formula C26H24FNO5 and CAS 873950-19-7 for unambiguous identification.
- Lot-specific purity and storage conditions available in the Certificate of Analysis.
Apexbio Technology LLC Sunitinib 557795-19-4 100mg
Sunitinib (CAS 557795-19-4) is an orally bioavailable small molecule inhibitor targeting multiple receptor tyrosine kinases (RTKs) including VEGFR1-3 PDGFR / c-kit and RET Research has shown sunitinib inhibits proliferation in nasopharyngeal carcinoma (NPC) cell lines HK1 CNE-1 CNE-2 HONE-1 and C666-1 with IC50 values ranging from approximately 2 06 to 7 57 M Additionally it induces apoptosis and G0/G1 cell cycle arrest in NPC cell lines and significantly decreases microvessel density in CNE-2 xenograft tumor models in vivo Thus sunitinib is useful for investigating pathways involved in tumor angiogenesis and proliferation
Apexbio Technology LLC Sunitinib 557795-19-4 10mM (in 1mL DMSO)
Sunitinib (CAS 557795-19-4) is an orally bioavailable small molecule inhibitor targeting multiple receptor tyrosine kinases (RTKs) including VEGFR1-3 PDGFR / c-kit and RET Research has shown sunitinib inhibits proliferation in nasopharyngeal carcinoma (NPC) cell lines HK1 CNE-1 CNE-2 HONE-1 and C666-1 with IC50 values ranging from approximately 2 06 to 7 57 M Additionally it induces apoptosis and G0/G1 cell cycle arrest in NPC cell lines and significantly decreases microvessel density in CNE-2 xenograft tumor models in vivo Thus sunitinib is useful for investigating pathways involved in tumor angiogenesis and proliferation
Apexbio Technology LLC Sunitinib 557795-19-4 1g
Sunitinib (CAS 557795-19-4) is an orally bioavailable small molecule inhibitor targeting multiple receptor tyrosine kinases (RTKs) including VEGFR1-3 PDGFR / c-kit and RET Research has shown sunitinib inhibits proliferation in nasopharyngeal carcinoma (NPC) cell lines HK1 CNE-1 CNE-2 HONE-1 and C666-1 with IC50 values ranging from approximately 2 06 to 7 57 M Additionally it induces apoptosis and G0/G1 cell cycle arrest in NPC cell lines and significantly decreases microvessel density in CNE-2 xenograft tumor models in vivo Thus sunitinib is useful for investigating pathways involved in tumor angiogenesis and proliferation