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Filtered Search Results
Medchemexpress LLC Boc-NH-PEG2-NH-Boc | 475591-59-4 | ≥97.0% | C16H32N2O6 | 500 MG
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Boc-NH-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used as a PROTAC linker for synthesizing PROTACs
- Utilized to selectively degrade target proteins
- Leverages the intracellular ubiquitin-proteasome system
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Medchemexpress LLC O-proparagyl-N-Boc-ethanolamine | 634926-63-9 | MFCD22418470 | 95.0% | 199.25 g/mol | C10H17NO3 | 500 MG
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O-Proparagyl-N-Boc-ethanolamine is a Boc-protected ethanolamine bearing a propargyl (alkyne) functional group. It serves as a synthetic building block and alkyne handle for organic synthesis, enabling conjugation via click chemistry and incorporation as a linker or crosslinker in medicinal chemistry applications. Supplied as a solid reagent for routine laboratory synthesis and derivatization.
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Medchemexpress LLC Boc-6-aminohexanoic acid | 6404-29-1 | 231.29 | 25 G
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Boc-6-aminohexanoic acid is an alkyl/ether-based PROTAC linker designed for the synthesis of PROTACs. These compounds exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins by linking a ligand for an E3 ubiquitin ligase with a ligand for the target protein. This product is for research use only.
- Alkyl/ether-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Purity of 98.0%
- Molecular weight of 231.29
- Appearance as a white to off-white solid
- Soluble in H2O at 50 mg/mL (requires ultrasonic)
- Stable as powder at -20°C for 3 years, or 4°C for 2 years
- Stable in solvent at -80°C for 6 months, or -20°C for 1 month
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Medchemexpress LLC Carbonic Anhydrase 1 10ug
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Carbonic Anhydrase 10 Protein a member of the carbonic anhydrase family plays a role in the regulation of pH and ion transport It is expressed in various tissues including the brain liver and kidney The potential involvement of Carbonic Anhydrase 10 Protein in diseases and its physiological functions make it a subject of interest in biomedical research Carbonic Anhydrase 10 Protein Mouse (HEK293 His) is the recombinant mouse-derived Carbonic Anhydrase 10 protein expressed by HEK293 with C-His labeled tag
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Medchemexpress LLC 1-BOC-4-(2-Hydroxyethyl)piperazine-d4 | 1219802-10-4 | 99% | 234.33 | 25 MG
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1-BOC-4-(2-Hydroxyethyl)piperazine-d4 is the deuterium labeled 1-BOC-4-(2-Hydroxyethyl)piperazine. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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Sigma Aldrich Fine Chemicals Biosciences 1-Methyl-2-pyrrolidinone A
1-Methyl-2-pyrrolidinone A
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Medchemexpress LLC Tert-butyl 4-(4-aminobutyl)piperazine-1-carboxylate | 745048-07-1 | MFCD04038543 | 257.37 | C13H27N3O2 | 100 MG
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1-Boc-4-(4-aminobutyl)piperazine is a Boc-protected piperazine derivative used as a drug intermediate for the synthesis of active pharmaceutical compounds. It is offered in multiple laboratory-scale pack sizes for medicinal chemistry and organic synthesis applications.
- Boc-protected piperazine scaffold suitable for medicinal chemistry.
- Available in multiple lab-scale pack sizes, including 100 MG.
- Molecular formula C13H27N3O2 and molecular weight 257.37.
- Intended as a synthetic intermediate for the preparation of diverse active compounds.
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Medchemexpress LLC N-(Azido-PEG2)-N-Boc-PEG4-NHS ester | 2093153-95-6 | Pure form | C26H45N5O12 | 100 MG
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N-(Azido-PEG2)-N-Boc-PEG4-NHS ester is a versatile PEG-based PROTAC linker. It is commonly employed in the synthesis of PROTACs, which are bifunctional molecules designed to induce targeted protein degradation. This compound also functions as a click chemistry reagent, featuring an Azide group. This Azide group enables it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions when combined with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Utilized in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an Azide group
- Facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Supports strain-promoted alkyne-azide cycloaddition (SPAAC)
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Medchemexpress LLC Boc-NH-PEG-amine (MW 5000) | ≥98.0% | 50 MG
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Boc-NH-PEG-amine (MW 5000) is a PEG-based PROTAC linker designed for the synthesis of PROTACs. PROTACs utilize an intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting a ligand for an E3 ubiquitin ligase and a ligand for the target protein. This product is provided as a solid, white to off-white appearance, with a purity of ≥98.0%. It is intended for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system for selective protein degradation
- Solid, white to off-white appearance
- Purity of ≥98.0%
- Average molecular weight of 5000
- Stable under recommended storage conditions
- Available in various quantities for research
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Medchemexpress LLC Carbonic Anhydrase 2 5ug
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Carbonic Anhydrase 2 (CA2) catalyzes the reversible hydration of carbon dioxide Mutations in CA2 are linked to osteopetrosis and renal tubular acidosis The gene exhibits biased expression in various tissues notably in the stomach and colon Two transcript variants encoding different isoforms have been identified Carbonic Anhydrase 2 Protein Human (C-His) is the recombinant human-derived Carbonic Anhydrase 2 protein expressed by E coli with C-6 His labeled tag
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Medchemexpress LLC Azido-PEG2-C2-Boc | 1271728-79-0 | 95.0% | C11H21N3O4 | 100 MG
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Azido-PEG2-C2-Boc is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This compound functions as a click chemistry reagent, containing an Azide group that facilitates copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules possessing Alkyne groups. It can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Serves as a PEG-based linker for PROTAC construction.
- Features an azide group enabling CuAAc reactions with alkyne-containing molecules.
- Capable of strain-promoted alkyne-azide cycloaddition with molecules containing DBCO or BCN groups.
- PROTACs leverage the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
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Medchemexpress LLC 3,6,9,16-Tetraoxaheptadecanoic acid, 17-phenyl-, 1,1-dimethylethyl ester | 2381196-81-0 | 95.8% | 100 MG
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Boc-C1-PEG3-C4-OBn is a PROTAC linker, which refers to the PEG composition. It can be used in the synthesis of various PROTACs. PROTACs consist of two distinct ligands linked by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PROTAC linker with PEG composition
- Can be used in the synthesis of various PROTACs
- Targets an E3 ubiquitin ligase and a protein of interest
- Leverages the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
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Medchemexpress LLC Boc-Aminooxy-PEG4-Tos | 1807539-01-0 | C20H33NO9S | 250 MG
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Boc-Aminooxy-PEG4-Tos is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. PROTACs are innovative molecules that harness the intracellular ubiquitin-proteasome system to selectively degrade target proteins by linking a ligand for an E3 ubiquitin ligase with a ligand for the target protein.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system for selective protein degradation
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Azido-PEG2-C1-Boc | 251564-45-1 | C10H19N3O4 | 250 MG
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Azido-PEG2-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is a versatile click chemistry reagent.
- Click chemistry reagent containing an azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
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Medchemexpress LLC N-(Azido-PEG2)-N-Boc-PEG4-NHS ester | 2093153-95-6 | C26H45N5O12 | 250 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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N-(Azido-PEG2)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It acts as a click chemistry reagent, facilitating reactions with molecules containing Alkyne, DBCO, or BCN groups through its Azide functionality. This product is designed for research applications.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with Alkyne groups
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
- Intended for research use only
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