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Filtered Search Results
Medchemexpress LLC Z-LEHD-FMK | 210345-04-3 | 98.1% | 690.72 | 50 MG
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Z-LEHD-FMK is a selective and irreversible inhibitor of caspase-9. It protects against lethal reperfusion injury, attenuates apoptosis, and demonstrates neuroprotective effects in a rat model of spinal cord trauma. This compound is a potent tool for research into apoptosis and neuroprotection.
- Selective and irreversible inhibitor of caspase-9
- Protects against lethal reperfusion injury
- Attenuates apoptosis
- Neuroprotective effect in spinal cord trauma models
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Medchemexpress LLC Z-LEHD-FMK | 210345-04-3 | 98.1% | 690.72 | 5 MG
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Z-LEHD-FMK is a selective and irreversible inhibitor of caspase-9. It protects against lethal reperfusion injury and attenuates apoptosis, also demonstrating a neuroprotective effect in a rat model of spinal cord trauma.
- Selective and irreversible caspase-9 inhibitor
- Protects against lethal reperfusion injury
- Attenuates apoptosis
- Neuroprotective in spinal cord trauma models
- Purity: 98.1%
- Molecular Weight: 690.72
- Appearance: Solid, white to yellow
- Solubility: 100 mg/mL in DMSO
- Storage (powder): -80°C for 2 years, -20°C for 1 year
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month (sealed, away from moisture)
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Medchemexpress LLC Z-WEHD-FMK | 210345-00-9 | 98.0% | 763.77 | 25 MG
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Z-WEHD-FMK is a potent, cell-permeable, and irreversible caspase-1/5 inhibitor. It also demonstrates a robust inhibitory effect on cathepsin B activity with an IC50 of 6 μM, and can be utilized to investigate cells for evidence of apoptosis.
- Potent, cell-permeable, and irreversible caspase-1/5 inhibitor
- Demonstrates a robust inhibitory effect on cathepsin B activity
- Utilized to investigate cells for evidence of apoptosis
- Appears as a light yellow to yellow solid
- Soluble in DMSO
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Medchemexpress LLC 2-methyl-6-(2-phenylethenyl)pyridine | 6266-99-5 | MFCD02262120 | 99.8% | 195.26 g·mol⁻¹ | C14H13N | 1 ML
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(E/Z)-SIB-1893 is a racemic mixture of the (E)- and (Z)-isomers of SIB-1893, a selective non-competitive antagonist of the metabotropic glutamate receptor subtype 5 (mGluR5). It is supplied as a 10 mM solution in DMSO for research use.
- Racemic mixture of (E)- and (Z)-isomers.
- Selective non-competitive mGluR5 antagonist.
- Supplied as 10 mM solution in DMSO, 1 mL vial.
- Purity 99.8%.
- Molecular weight 195.26 g·mol⁻¹; formula C14H13N.
- Store per manufacturer recommendations: powder -20°C (3 years) or 4°C (2 years).
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Medchemexpress LLC Z,E-9,12-tetradecadien-1-ol | 42521-46-0 | MFCD00270832 | 210.36 g/mol | C14H26O | 5mg
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(Z E)-9 12-Tetradecadienol is a synthetic enhancer of male Ephestia cautella attraction[1]
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![Medchemexpress LLC Thiazolidine, 3-[(2,3-dihydro-1H-inden-2-yl)acetyl]-4-(1-pyrrolidinylcarbonyl)-, (4R)- | 130849-58-0 | 99.7% | 344.47 g/mol | C19H24N2O2S | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000295327.png-250.jpg)
Medchemexpress LLC Thiazolidine, 3-[(2,3-dihydro-1H-inden-2-yl)acetyl]-4-(1-pyrrolidinylcarbonyl)-, (4R)- | 130849-58-0 | 99.7% | 344.47 g/mol | C19H24N2O2S | 10 MG
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Z-321 is a small-molecule prolyl endopeptidase (PEP) inhibitor provided as a high-purity research reagent for use in in vitro and in vivo studies. Follow supplied safety, handling, and storage recommendations when preparing and using this compound.
- High purity suitable for research applications.
- Supplied with certificate of analysis and analytical data.
- Provided as a stable powder for long-term storage.
- Includes structural identifiers and SMILES for informatics use.
- Recommended storage conditions extend shelf life and stability.
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Medchemexpress LLC (Z)-Non-6-en-1-ol | 35854-86-5 | MFCD00015388 | 142.24 g·mol⁻¹ | C9H18O | 1 G
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(Z)-Non-6-en-1-ol (cis-6-nonen-1-ol) is an unsaturated primary alcohol supplied as a biochemical research reagent. It is intended for laboratory research use and has not been validated for medical applications.
- Chemical identity: (Z)-Non-6-en-1-ol; CAS 35854-86-5.
- Molecular formula C9H18O; molecular weight 142.24 g·mol⁻¹.
- Intended use: for research use only; not validated for medical applications.
- Storage recommendations: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Application category: biochemical assay reagent.
- Packaging: supplied in research-scale quantities suitable for laboratory use.
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TARGETMOL CHEMICALS INC Z-Capsaicin 50MG
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Also available in 10 mg and bulk. Please contact Fisher for quotes. (Z)-Capsaicin (Zucapsaicin) is a medication used to treat osteoarthritis of the knee and Others neuropathic pain.(Z)-Capsaicin is a synthetic cis isomer of natural capsaicin that has shown therapeutic efficacy in pain accompanying osteoarthritis of the knee. Purity 99.67%
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Medchemexpress LLC (Z)-Capsaicin | 25775-90-0 | 99.8% | 25 MG
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(Z)-Capsaicin is the cis isomer of capsaicin. It acts as an orally active TRPV1 agonist and is used in the research of neuropathic pain.
- Acts as a TRPV1 agonist
- Used in the research of neuropathic pain
- Exhibits agonist activity at human TRPV1 expressed in CHO cells (EC50 of 28.2 nM)
- May also block neuronal calcium channels
- Significantly attenuates nociceptive behavior after oral administration in rats
- Tolerated in experimental genital herpes simplex virus infection in guinea pigs
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Medchemexpress LLC (E/Z)-Polydatin ((E/Z)-Piceid) | 65914-17-2 | 98.13% | 390.38 | 1 ML
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(E/Z)-Polydatin ((E/Z)-Piceid) is a mixture of the E/Z configurations of Polydatin (HY-N0120A). Polydatin can be isolated from Polygonum cuspidatum, grapes, peanuts, red wine, hop pellets, cocoa-containing products, and chocolate products. It exhibits multiple biological properties and shows favorable cytotoxic effects against various tumor cell lines.
- Exhibits anti-platelet aggregation
- Anti-low-density lipoprotein oxidation properties
- Cardioprotective activity
- Anti-inflammatory and immunomodulatory functions
- Shows cytotoxic effects against cervical cancer cells, liver cancer cells, and nasopharyngeal carcinoma cells
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Medchemexpress LLC Z-val-ala-asp | 162852-62-2 | 99.8% | 437.44 | 5 MG
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Z-VAD is an irreversible, broad-spectrum pan-caspase inhibitor that can inhibit a variety of caspases. It blocks apoptosis signaling pathways, induces autophagy and necrosis in tumor cells, and exhibits anti-angiogenic activity. It can also enhance the sensitivity of breast cancer and lung cancer cells to radiotherapy in vitro and in vivo, prolonging the growth delay of tumor xenograft models. Z-VAD is well tolerated and is primarily used in research concerning cancer radiosensitization and cell death pathway regulation.
- Inhibits a variety of caspases
- Blocks apoptosis signaling pathways
- Induces autophagy and necrosis in tumor cells
- Has anti-angiogenic activity
- Enhances sensitivity of breast and lung cancer cells to radiotherapy
- Prolongs growth delay of tumor xenograft models
- Well tolerated
- Mainly used in research related to cancer radiosensitization and cell death pathway regulation
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Apexbio Technology LLC Z-FA-FMK 105637-38-5;197855-65-5 25mg
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Z-FA-FMK is a peptidyl fluoromethyl ketone inhibitor targeting cysteine proteases specifically cathepsins such as cathepsin B and certain caspases It does not require a P1 aspartate residue for inhibition Mechanistically Z-FA-FMK suppresses the enzyme activity of effector caspases (including caspases-2 -3 -6 and -7) but shows minimal impact on initiator caspases (caspase-8 and caspase-10) and only partial attenuation of caspase-9 activity As a negative control inhibitor Z-FA-FMK is regularly applied in apoptosis research to differentiate specific caspase-dependent signaling pathways and to assess the role of cathepsins and caspases in biological contexts such as cell death mechanisms and related pathways
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Medchemexpress LLC (Z)-JQ1-TCO | 2087490-43-3 | 99.3% | 609.18 | 5 MG
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JQ1-TCO, a derivative of JQ1, functions as an inhibitor of BET. This compound is suitable for click chemistry applications and can be utilized as molecular probes in various research settings.
- Suitable for click chemistry
- Functions as an inhibitor of BET
- Used as molecular probes in vitro
- Used as molecular probes in vivo
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Cayman Chemical 3 Z 6 Z 9 Z 12 Z 15 ZOctadeca
A microalgal PUFA; has been used as a chemotaxonomic biomarker for microalgae and dinoflagellates
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Matrix Scientific 1-BENZYLOXYCARBONYL-3-PYRRO-5G
1-Benzyloxycarbonyl-3-pyrrolidinone, >95%-5g,C12H13NO3, mw 219.24,
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