Pyrrolidines
- (1)
- (250)
- (4)
- (2)
- (4)
- (1)
- (25)
- (3)
- (8)
- (53)
- (1)
- (9)
- (40)
- (3)
- (1)
- (3)
- (3)
- (1)
- (1)
- (3)
- (6)
- (1)
- (2)
- (1)
- (8)
- (1)
- (115)
- (2)
- (13)
- (18)
- (10)
- (3)
- (54)
- (1)
- (1)
- (1)
- (2)
- (217)
- (8)
- (5)
- (6)
- (10)
- (5)
- (1)
- (16)
- (38)
- (9)
- (6)
- (2)
- (1)
- (1)
- (4)
- (12)
- (12)
- (3)
- (4)
- (1)
- (10)
- (33)
- (2)
- (13)
- (1)
- (3)
- (6)
- (7)
- (9)
- (7)
- (8)
- (3)
- (8)
- (1)
- (1)
- (2)
- (8)
- (4)
- (2)
- (2)
- (12)
- (9)
- (1)
- (4)
- (1)
- (1)
- (2)
- (2)
- (1)
- (3)
- (2)
- (6)
- (2)
- (1)
- (2)
- (1)
- (3)
- (2)
- (4)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (3)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (5)
- (5)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (4)
- (2)
- (12)
- (3)
- (2)
- (4)
- (1)
- (5)
- (1)
- (1)
- (1)
- (3)
- (1)
- (7)
- (4)
- (5)
- (1)
- (1)
- (2)
- (1)
- (2)
- (6)
- (2)
- (1)
- (2)
- (2)
- (5)
- (2)
- (7)
- (9)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (2)
- (1)
- (2)
- (4)
- (2)
- (2)
- (4)
- (3)
- (2)
- (6)
- (5)
- (4)
- (1)
- (4)
- (1)
- (1)
- (2)
- (2)
- (4)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (4)
- (1)
- (1)
- (1)
- (4)
- (2)
- (2)
- (2)
- (4)
- (1)
- (1)
- (3)
- (6)
- (2)
- (1)
- (1)
- (3)
- (14)
- (1)
- (2)
- (1)
- (3)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (3)
- (9)
- (2)
- (1)
- (2)
- (2)
- (5)
- (3)
- (5)
- (1)
- (1)
- (1)
- (5)
- (2)
- (4)
- (1)
- (1)
- (1)
- (3)
- (4)
- (6)
- (3)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (11)
- (1)
- (5)
- (1)
- (1)
- (9)
- (1)
- (1)
- (4)
- (2)
- (2)
- (1)
- (2)
- (1)
- (3)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (4)
- (3)
- (4)
- (3)
- (1)
- (1)
- (2)
- (5)
- (1)
- (4)
- (2)
- (2)
- (2)
- (3)
- (1)
- (1)
- (1)
- (5)
- (2)
- (1)
- (2)
- (2)
- (2)
- (2)
- (3)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (2)
- (7)
- (3)
- (2)
- (1)
- (4)
- (3)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (11)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (3)
- (2)
- (1)
- (8)
- (2)
- (4)
- (1)
- (1)
- (1)
- (2)
- (5)
- (2)
- (3)
- (2)
- (4)
- (1)
- (2)
- (1)
- (4)
- (1)
- (4)
- (2)
- (1)
- (3)
- (1)
- (10)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (4)
- (4)
- (8)
- (1)
- (2)
- (1)
- (3)
- (4)
- (6)
- (1)
- (1)
- (12)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (9)
- (2)
- (4)
- (2)
- (1)
- (5)
- (2)
- (4)
- (4)
- (15)
- (2)
- (2)
- (3)
- (2)
- (3)
- (9)
- (1)
- (1)
- (33)
- (73)
- (3)
- (33)
- (20)
- (38)
- (13)
- (13)
- (41)
- (2)
- (1)
- (11)
- (2)
- (1)
- (2)
- (5)
- (3)
- (2)
- (3)
- (5)
- (3)
- (18)
- (47)
- (14)
- (158)
- (8)
- (107)
- (2)
- (2)
- (5)
- (1)
- (63)
- (4)
- (3)
- (3)
- (13)
- (248)
- (6)
- (5)
- (1)
- (15)
- (2)
- (2)
- (5)
- (3)
- (8)
- (3)
- (137)
- (3)
- (4)
- (1)
- (2)
- (39)
- (4)
- (2)
- (23)
- (54)
- (1)
- (2)
- (2)
- (2)
- (8)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (3)
- (2)
- (2)
- (4)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (4)
- (3)
- (2)
- (4)
- (2)
- (1)
- (1)
- (5)
- (4)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (3)
- (2)
- (2)
- (1)
- (2)
- (4)
- (1)
- (8)
- (1)
- (5)
- (3)
- (4)
- (2)
- (3)
- (1)
- (2)
- (2)
- (5)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (4)
- (1)
- (3)
- (1)
- (1)
- (4)
- (3)
- (2)
- (2)
- (1)
- (2)
- (4)
- (2)
- (2)
- (2)
- (3)
- (1)
- (1)
- (2)
- (3)
- (2)
- (2)
- (3)
- (2)
- (2)
- (3)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (2)
- (4)
- (1)
- (2)
- (3)
- (2)
Filtered Search Results
Medchemexpress LLC (S,R,S)-AHPC-PEG5-COOH | 2172820-14-1 | 99.8% | 100 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
(S,R,S)-AHPC-PEG5-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 5-unit PEG linker, commonly used in PROTAC technology. It functions by recruiting the VHL protein, a key substrate recognition subunit of Cullin RING E3 ubiquitin ligase complexes, to induce ubiquitination and subsequent proteasomal degradation of target proteins.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates (S,R,S)-AHPC based VHL ligand
- Includes 5-unit PEG linker
- Used in PROTAC technology
- Recruits VHL protein to induce ubiquitination
- Promotes proteasomal degradation of target proteins
- For research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
![Medchemexpress LLC (1R,2S)-2-[(3,5-dichlorophenyl)carbamoyl]cyclohexane-1-carboxylic acid | 1263273-14-8 | MFCD26142602 | 95.1% | C14H15Cl2NO3 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000259117.png-250.jpg)
Medchemexpress LLC (1R,2S)-2-[(3,5-dichlorophenyl)carbamoyl]cyclohexane-1-carboxylic acid | 1263273-14-8 | MFCD26142602 | 95.1% | C14H15Cl2NO3 | 10MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
(1R,2S)-VU0155041 is the cis regioisomer of VU0155041 and a research-grade small molecule characterized as a partial agonist of metabotropic glutamate receptor 4 (mGluR4). It is intended for in vitro laboratory use and has documented agonist activity with EC50 ≈ 2.35 μM; additional allosteric modulatory activity (~0.74 μM) has also been reported.
- IUPAC name: (1R,2S)-2-[(3,5-dichlorophenyl)carbamoyl]cyclohexane-1-carboxylic acid.
- Partial agonist activity at mGluR4 with EC50 ≈ 2.35 μM.
- Reported allosteric modulatory activity at ~0.74 μM in cell assays.
- Purity approximately 95.1% as supplied.
- Molecular formula C14H15Cl2NO3; molecular weight 316.18 g·mol-1.
- Supplied as a research reagent for in vitro use only; not for human use.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Aobchem AOBCHEM
5000967641 2- 2 2-DICHLORO-1-HYDROXYETHYL
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 1951424-91-1 | (3R)-3-amino-1-methyl-piperidin-2-one hydrochloride | Pharmablock | MFCD26954783 | 164.630 | C6H13ClN2O | 97.000 | Cl.CN1CCC[C@@H](N)C1=O | 1g | 799224731
(3R)-3-amino-1-methyl-piperidin-2-one hydrochloride | Pharmablock | 1951424-91-1 | MFCD26954783 | 164.630 | C6H13ClN2O | 97.000 | Cl.CN1CCC[C@@H](N)C1=O | 1g | 799224731
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
C(O)=O | 1g | 784550629](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000473655.jpg-250.jpg)
eMolecules 63039-48-5 | (2S)-2-(tert-butoxycarbonylamino)pent-4-ynoic acid | Pharmablock | MFCD01320855 | 213.233 | C10H15NO4 | 97.000 | CC(C)(C)OC(=O)N[C@@H](CC#C)C(O)=O | 1g | 784550629
(2S)-2-(tert-butoxycarbonylamino)pent-4-ynoic acid | Pharmablock | 63039-48-5 | MFCD01320855 | 213.233 | C10H15NO4 | 97.000 | CC(C)(C)OC(=O)N[C@@H](CC#C)C(O)=O | 1g | 784550629
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Sigma Aldrich Fine Chemicals Biosciences Kainic acid monohydrate >=98% (HPLC), from Digenea simplex | 58002-62-3 | MFCD00150833 | 50MG
Kainic acid monohydrate >=98% (HPLC), from Digenea simplex | Purity: >=98% (HPLC) | Mol Wt: 231.25 | 58002-62-3 | MFCD00150833 | 50MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Sigma Aldrich Fine Chemicals Biosciences Kainic acid monohydrate >=98% (HPLC), from Digenea simplex | 58002-62-3 | MFCD00150833 | 10MG
Kainic acid monohydrate >=98% (HPLC), from Digenea simplex | Purity: >=98% (HPLC) | Mol Wt: 231.25 | 58002-62-3 | MFCD00150833 | 10MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Sigma Aldrich Fine Chemicals Biosciences Atto 488 maleimide BioReag1MG
ATTO Atto 488 maleimide BioReag1MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Aobchem AOBCHEM
5000979975 5-BROMO-4-METHYL-2- PYRROLIDIN
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Protac EED degrader-1 | 2639882-72-5 | 98.3% | C55H60FN11O8S | 10MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
PROTAC EED degrader-1 is a von Hippel-Lindau (VHL)-based proteolysis targeting chimera designed to bind and induce degradation of EED, a subunit of the polycomb repressive complex 2 (PRC2). It exhibits potent biochemical and cellular activity, leads to downregulation of EZH2 and H3K27me3, and has shown cellular apoptosis and antitumor effects in preclinical models.
- Potent EED-targeting degrader with low nanomolar biochemical activity.
- Reduces EZH2 protein levels and decreases H3K27me3 in cells.
- Induces apoptosis and shows antitumor activity in preclinical models.
- High reported purity for research applications.
- Available in multiple small-scale quantities for laboratory studies.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC MEDCHEMEXPRESS LLC
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
5000740967 PYRROLIDIN-2-YL-ACET 10MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
![Medchemexpress LLC 3-[[4-(2-pyridinyl)-2-thiazolyl]amino]phenol | 315702-75-1 | MFCD01121976 | 100.0% | C14H11N3OS | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000261845.png-250.jpg)
Medchemexpress LLC 3-[[4-(2-pyridinyl)-2-thiazolyl]amino]phenol | 315702-75-1 | MFCD01121976 | 100.0% | C14H11N3OS | 10MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
KCC-07 is a brain-penetrant small molecule inhibitor of MBD2 (methyl-CpG-binding domain protein 2) that prevents MBD2 binding to methylated DNA and activates BAI1-p53-p21 signaling to produce antiproliferative effects. It is supplied as a solid and as a 10 mM solution in DMSO, with reported high purity and recommended storage conditions for research use.
- Inhibits MBD2 binding to methylated DNA.
- Blood-brain barrier penetrant.
- Activates BAI1-p53-p21 antiproliferative signaling.
- High purity suitable for research applications.
- Soluble at high concentration in DMSO.
- Available as solid and as 10 mM DMSO solution.
- Storage recommendations provided for long-term stability.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Lumiprobe LUMIPROBE
NC4035645 AF 647 MALEIMIDE 25 MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC MEDCHEMEXPRESS LLC
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
5000745813 N-AZIDO-PEG2-N-BIO 500MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Aobchem AOBCHEM
5000971095 1- 6- PYRROLIDIN-1-YL PYRIDIN-
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More