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Filtered Search Results
Medchemexpress LLC Milademetan tosylate hydrate | 2095625-97-9 | 808.74 | C37H44Cl2FN5O8S
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Milademetan tosylate hydrate is the tosylate hydrate salt form of milademetan, an orally active MDM2 inhibitor supplied for research use. It is intended for preclinical studies investigating MDM2-p53 pathway modulation and compound screening.
- Tosylate hydrate salt form of milademetan.
- Selective MDM2 inhibitor suitable for preclinical research.
- Supplied in small research quantities appropriate for screening and assay development.
- Recommended storage: sealed at 4°C; in solvent store at -80°C (6 months) or -20°C (1 month).
- For research use only; not validated for clinical applications.
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Medchemexpress LLC Milademetan tosylate hydrate | 2095625-97-9 | 98.9% | 808.74 g/mol | C37H44Cl2FN5O8S | 100 MG
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Milademetan tosylate hydrate is the tosylate hydrate salt form of milademetan (DS-3032), an orally active MDM2 inhibitor provided as a characterized research compound for oncology studies focused on p53-MDM2 interactions. The material is supplied with analytical data and a certificate of analysis.
- Orally active MDM2 inhibitor
- Intended for oncology research and p53-MDM2 studies
- High purity (98.9%) with available certificate of analysis
- Molecular weight 808.74 g/mol
- Supplied in measured quantities, commonly 100 MG
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Medchemexpress LLC Terlipressin diacetate | 1884420-36-3 | 99.8% | 1347.48 | C56H82N16O19S2 | 100MG
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Terlipressin diacetate is a vasopressin analogue and a selective vasopressin V1 receptor agonist used in research to reduce splanchnic blood flow and portal pressure. It is applied in studies of acute variceal bleeding, hepatorenal syndrome, and norepinephrine-resistant septic shock, and shows anti-inflammatory and anti-oxidative effects. Supplied as a purified peptide with recommended frozen storage to preserve stability.
- High purity suitable for research applications.
- Selective vasopressin V1 receptor agonist activity.
- Relevant for models of portal hypertension and variceal bleeding.
- Exhibits anti-inflammatory and anti-oxidative properties.
- Storage recommendations minimize degradation and extend shelf life.
- Available in multiple pack sizes for flexible experimental needs.
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Medchemexpress LLC Act-462206 | 1361321-96-1 | MFCD28502270 | 99.5% | 388.48 | C20H24N2O4S | 25 MG
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ACT-462206 is an orally active, brain-penetrant dual orexin (OX1/OX2) receptor antagonist used in neuroscience research into sleep, anxiety, and addiction. The compound shows low-nanomolar activity at orexin receptors and is supplied as a high-purity solid or solution format for laboratory use (research use only).
- Dual orexin receptor antagonist with low-nanomolar potency (OX1 and OX2)
- Brain-penetrant properties suitable for CNS pharmacology studies
- High purity (~99.5%) for reliable biochemical and pharmacological testing
- Soluble in DMSO at ≥100 mg/mL for in vitro preparations
- Available in research-scale solid and solution formats
- Stored and shipped under recommended conditions to preserve stability
- For research use only, not for human or clinical use
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Medchemexpress LLC (S,R,S)-AHPC-phenol-C4-NH2 dihydrochloride | 2376990-26-8 | >98.0% | C28H43Cl2N5O5S | 10MG
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(S,R,S)-AHPC-phenol-C4-NH2 dihydrochloride is a small-molecule VHL ligand derivative supplied as the dihydrochloride salt for use in PROTAC and E3 ligase recruitment research. It is reported as a solid reagent with high purity and is accompanied by analytical documentation suitable for research and development (R&D) applications.
- Used for VHL recruitment in PROTAC design and protein degradation studies.
- Provided as a dihydrochloride salt for improved solubility and handling.
- High reported purity suitable for chemical biology research.
- Supplied in small-scale pack sizes for research and development use.
- Accompanied by analytical data such as COA and SDS for quality verification.
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Medchemexpress LLC WSB1 Degrader 1 | 2306039-66-5 | MFCD34368539 | 99.8% | 334.41 g·mol⁻1 | C21H22N2O2 | 5 MG
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WSB1 Degrader 1 is a small-molecule research degrader that targets WSB1 (WD repeat and SOCS box-containing 1). It is described as potent and orally active with demonstrated anticancer and anti-metastatic effects, intended for biochemical, cellular, and early in vivo studies.
- Potent degrader of WSB1 with reported anticancer and anti-metastatic effects.
- Orally active in preclinical studies, suitable for in vivo research.
- High purity (99.81%), appropriate for sensitive assays.
- Good solubility in DMSO (25 mg/mL) and formulatable for in vivo use.
- Stable when stored as a powder under recommended conditions.
- Available in small research pack sizes for early-stage experiments.
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Apexbio Technology LLC Alarelin Acetate,50mg CAS# 79561-22-1
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Alarelin (Gonadotrophin-releasing hormone) is a synthetic GnRH agonist. Alarelin is found in higher amounts than that of LH-RH in rat hypophyseal stimulation of gonadotropin secretion in vivo and in vitro and in ovulation inductions. Alarelin is known for its induction of ovulation and is used to treat endmometriosis. Alarelin Acetate is the acetate form of a hypothalamic peptide that stimulates the release of FSH and LH from the pituitary gland. Other sizes are also available. Please inqury us for quote.
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Medchemexpress LLC Protac CRBN degrader-1 | 2358775-70-7 | MFCD32197292 | 98.8% | 1061.25 g/mol | C53H72N8O13S | 5 MG
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PROTAC CRBN Degrader-1 is a research-grade proteolysis-targeting chimera that induces selective degradation of cereblon (CRBN) by promoting heterodimerization with VHL, enabling studies of targeted protein degradation and ubiquitin-proteasome-mediated pathways. Supplied as a purified small-molecule for in vitro and cellular research; not for human or diagnostic use.
- Selective CRBN degradation via VHL-CRBN heterodimerization.
- High purity suitable for biochemical and cellular assays.
- Available in small-milligram research quantities.
- Molecular formula C53H72N8O13S and molecular weight 1061.25 g/mol.
- Accompanied by product documentation including SDS and COA.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Protac EED degrader-1 | 2639882-72-5 | 98.3% | C55H60FN11O8S | 10MG
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PROTAC EED degrader-1 is a von Hippel-Lindau (VHL)-based proteolysis targeting chimera designed to bind and induce degradation of EED, a subunit of the polycomb repressive complex 2 (PRC2). It exhibits potent biochemical and cellular activity, leads to downregulation of EZH2 and H3K27me3, and has shown cellular apoptosis and antitumor effects in preclinical models.
- Potent EED-targeting degrader with low nanomolar biochemical activity.
- Reduces EZH2 protein levels and decreases H3K27me3 in cells.
- Induces apoptosis and shows antitumor activity in preclinical models.
- High reported purity for research applications.
- Available in multiple small-scale quantities for laboratory studies.
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![Medchemexpress LLC (2S)-N-(3,5-Dimethylphenyl)-1-[(4-methoxyphenyl)sulfonyl]-2-pyrrolidinecarboxamide | 1361321-96-1 | MFCD28502270 | 99.5% | 388.48 g/mol | C20H24N2O4S | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000249301.png-250.jpg)
Medchemexpress LLC (2S)-N-(3,5-Dimethylphenyl)-1-[(4-methoxyphenyl)sulfonyl]-2-pyrrolidinecarboxamide | 1361321-96-1 | MFCD28502270 | 99.5% | 388.48 g/mol | C20H24N2O4S | 10 MG
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ACT-462206 is an orally active, brain-penetrant dual orexin 1/2 receptor antagonist used in neuroscience research to probe orexin signaling and to evaluate behavioral pharmacology. It shows low-nanomolar potency at orexin receptors and is supplied as a high-purity research chemical available in both solid form and as a DMSO solution.
- Potent dual orexin receptor antagonist with low-nanomolar activity.
- Brain-penetrant profile suitable for in vivo studies.
- High purity for reproducible experimental results.
- Available as solid and DMSO solution for dosing flexibility.
- Stable when stored under recommended conditions and protected from light.
- Applicable for pharmacological and behavioral neuroscience research.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC HY-10900 10mg Medchemexpress, TCS 1102 CAS:916141-36-1 Purity:>98%
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Medchemexpress, HY-10900 10mg TCS 1102 CAS:916141-36-1 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Selleck Chemical LLC ACT-1016-0707-E1941-5MG
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ACT-1016-0707 (LPA1 receptor antagonist 2) is an orally active and selective antagonist of LPA1 Receptor with IC50 of 3 1 nM for hLPAR1 in tango assay It has the potential to treat fibrotic diseases
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Medchemexpress LLC Protac SGK3 degrader-1 (synonyms: SGK3-PROTAC1) | 2381320-35-8 | 99.9% | 1157.38 g·mol-1 | C57H73FN10O11S2 | 5MG
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PROTAC SGK3 degrader-1 is a VHL-ligand based proteolysis targeting chimera designed to induce ubiquitin-proteasome-mediated degradation of SGK3. Supplied as a solid for research use, it is characterized by analytical methods for identity and purity and is intended for cellular degradation studies, chemical biology, and mechanistic investigation of SGK3 signaling.
- Induces degradation of SGK3 in cell-based assays.
- Characterized by molecular formula C57H73FN10O11S2 and molecular weight 1157.38 g·mol-1.
- High purity suitable for biochemical and cellular studies.
- Supplied in small research pack sizes for laboratory use.
- Analytical data such as NMR and HPLC provided to support identity and purity.
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Medchemexpress LLC PROTAC EED degrader-2 | 2639882-69-0 | 99.9% | C50H58FN11O6S | 10MG
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PROTAC EED degrader-2 is a VHL-based proteolysis-targeting chimera that binds EED, a subunit of the polycomb repressive complex 2 (PRC2), promoting its ubiquitination and degradation. The compound demonstrates potent PRC2 inhibition in biochemical and cellular assays and is supplied as a high-purity solid for laboratory research use only.
- induces targeted degradation of EED in cellular assays
- demonstrates potent PRC2 inhibition (pIC50 ≈ 8.11)
- high chemical purity suitable for biochemical studies
- solid, white to off-white form with defined storage recommendations
- detailed structural and analytical data available from supplier records
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![Enzo Life Sciences ET A receptor antagonist [BQ-610] (1mg). CAS: 141595-53-1](https://assets.fishersci.com/TFS-Assets/CCG/product-images/ENZOLOGO.png-250.jpg)
Enzo Life Sciences ET A receptor antagonist [BQ-610] (1mg). CAS: 141595-53-1
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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30-fold more potent ETA antagonist than BQ-123 in pig aortic smooth muscle membrane assay, same activity as BQ-123 when tested on pig cerebellum membrane. Formula: C36H44N6O6. MW: 656.8. Long Term Storage: -20°C.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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