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Filtered Search Results
Aobchem AOBCHEM
5001072946 N N-DIMETHYL-5- PYRROLIDIN-1-Y
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Medchemexpress LLC (E/Z)-Teriflunomide | 108605-62-5 | 99.87% | 270.21 | 1 ML
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(E/Z)-Teriflunomide is the active metabolite of Leflunomide and functions as an immunomodulatory agent. It exerts its effects by inhibiting the mitochondrial enzyme dihydroorotate dehydrogenase (DHODH), which plays a crucial role in pyrimidine synthesis. This compound also acts as a non-steroidal anti-inflammatory drug and a tyrosine kinase inhibitor. It is utilized in the treatment of relapsing forms of multiple sclerosis and rheumatoid arthritis.
- Active metabolite of Leflunomide
- Immunomodulatory agent
- Inhibits mitochondrial enzyme dihydroorotate dehydrogenase (DHODH)
- Functions as a non-steroidal anti-inflammatory drug
- Functions as a tyrosine kinase inhibitor
- Inhibits pyrimidine synthesis
- Used to treat relapsing forms of multiple sclerosis
- Used to treat rheumatoid arthritis
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Medchemexpress LLC N-Boc-dolaproine | 120205-50-7 | 100.0% | 287.36 | 1 G
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N-Boc-dolaproine ((2R,3R)-BOC-dolaproine) is an amino acid residue of the pentapeptide Dolastatin 10. Dolastatin 10 inhibits tubulin polymerization and mitosis and possesses anticancer activity. This product is a key intermediate utilized in the synthesis of Dolastatin 10.
- Amino acid residue of Dolastatin 10
- Inhibits tubulin polymerization and mitosis
- Possesses anticancer activity
- Key intermediate for synthesis of Dolastatin 10
- Colorless to light yellow oil
- Ships at room temperature in continental US
- Store at 4°C under nitrogen
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Medchemexpress LLC Boc-C1-PEG2-C4-Cl (PROTAC Linker 1) | 1835705-53-7 | 99.8% | 294.81 | 100 MG
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Boc-C1-PEG2-C4-Cl (PROTAC Linker 1) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. This technology utilizes small molecules to recruit target proteins for ubiquitination and removal by the proteasome. It can mediate the degradation of c-ABL and BCR-ABL by recruiting Cereblon or Von Hippel Lindau E3 ligases.
- Appearance: liquid (density: 1.026±0.06 g/cm³)
- Color: colorless to light yellow
- Used in the synthesis of PROTACs
- Facilitates the degradation of oncogenic BCR-ABL
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Medchemexpress LLC tert-Butoxycarbonyl-D-valine | 22838-58-0 | ≥97.0% | 217.26 | 500 G
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tert-Butoxycarbonyl-D-valine is a valine derivative. Amino acids and amino acid derivatives have been commercially used as ergogenic supplements, influencing the secretion of anabolic hormones, supplying fuel during exercise, improving mental performance during stress-related tasks, and preventing exercise-induced muscle damage. They are recognized as beneficial ergogenic dietary substances.
- Influences the secretion of anabolic hormones.
- Supplies fuel during exercise.
- Improves mental performance during stress-related tasks.
- Prevents exercise-induced muscle damage.
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Medchemexpress LLC Boc-C5-O-C5-O-C6-Cl | 1835705-52-6 | 393.00 | 50 MG
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Boc-C5-O-C5-O-C6-Cl (PROTAC Linker 2) is a PROTAC linker utilized to connect the respective tyrosine kinase inhibitor (TKI) to the E3 recruiting ligand. It is for research use only.
- PROTAC linker utilized to connect the respective tyrosine kinase inhibitor (TKI) to the E3 recruiting ligand.
- Alkyl/ether linker type.
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Medchemexpress LLC 6-azido-N-acetylgalactosamine-UDP | 1202854-87-2 | 100.0% | 632.37 | C17H26N6O16P2 | 10 MG
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6-Azido-N-acetylgalactosamine-UDP is a UDP-activated azido-modified sugar donor used as an enzymatic substrate in glycosylation assays, including beta-1,3-N-acetylhexosaminyltransferase (LgtA)-catalyzed glycosylation of lactose. The reagent is supplied as a white to off-white solid with high purity for biochemical research and storage at low temperatures.
- High purity (99.95%).
- Molecular weight 632.37 g/mol.
- Chemical formula C17H26N6O16P2.
- Physical form: solid, white to off-white.
- Suggested storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Available sizes include 5 mg-500 mg (larger sizes by quote).
- Intended use: enzymatic glycosylation studies and biochemical assays.
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![eMolecules 1009075-44-8 | Tert-Butyl ((1R,3R)-3-Aminocyclopentyl)Carbamate | AA Blocks LLC200.282 | C10H20N2O2 | 0.000 | CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](N)C1 | 250mg | 410143413](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000130846.jpg-250.jpg)
eMolecules 1009075-44-8 | Tert-Butyl ((1R,3R)-3-Aminocyclopentyl)Carbamate | AA Blocks LLC200.282 | C10H20N2O2 | 0.000 | CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](N)C1 | 250mg | 410143413
Tert-Butyl ((1R,3R)-3-Aminocyclopentyl)Carbamate | AA Blocks LLC | 1009075-44-8200.282 | C10H20N2O2 | 0.000 | CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](N)C1 | 250mg | 410143413
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Aobchem AOBCHEM
5000908019 2-FLUORO-4- HYDROXYMETHYL -3-
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Medchemexpress LLC (S,R,S)-AHPC-phenol-C4-NH2 dihydrochloride | 2376990-26-8 | 96.33% | 632.64 | 100 MG
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(S,R,S)-AHPC-phenol-C4-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used in PROTAC technology. It is for research use only and not sold to patients.
- Contains two different ligands connected by a linker
- One ligand for an E3 ubiquitin ligase
- Other ligand for the target protein
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Aobchem AOBCHEM
5000999320 3-FLUORO-2- HYDROXYMETHYL -6-
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000772935 N-METHYLMALEIMIDE 5G
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Aobchem AOBCHEM
5000903679 3- 4- TERT-BUTOXYCARBONYL PI
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eMolecules 7154-73-6 | Pyrrolidinoethylamine | Ambeed | MFCD00003182 | 114.192 | C6H14N2 | 98 | NCCN1CCCC1 | 1g | 490550478
Pyrrolidinoethylamine | Ambeed | 7154-73-6 | MFCD00003182 | 114.192 | C6H14N2 | 98.000 | NCCN1CCCC1 | 1g | 490550478
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GRAINGER INC 5-METHYL-2-PYRROLIDONE 25G
502780949 5-METHYL-2-PYRROLIDONE 25G
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