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Filtered Search Results
Cayman Chemical BIsIndolylmaleImIde II 1mg
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A general inhibitor of all PKC subtypes with structural similarity to the nonspecific PKC inhibitor staurosporine; inhibits PDK1 (IC50 = 14 μM) and PKA (IC50 = 2.94 μM)
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eMolecules 3-N-CBZ-AMINOMETHYLANILINE HCL | 1159826-16-0 | MFCD09878799 | 5g
AstaTech | 3-N-CBZ-AMINOMETHYLANILINE HCL | 5g | 112525477 | 58131 | 97.000 | 1159826-16-0 | MFCD09878799 | 292.760 | C15H17ClN2O2
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eMolecules Ambeed / (2R3R)-Butane-23-diol / 1g / 491166804 / A114648 / / 24347-58-8 / MFCD00064267 / 90.122 / C4H10O2
Ambeed / (2R3R)-Butane-23-diol / 1g / 491166804 / A114648 / / 24347-58-8 / MFCD00064267 / 90.122 / C4H10O2
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eMolecules (S)-2-((TERT-BUTOXYCARBONYL)AMINO)-2-(4,4-DIFLUOROCYCLOHEXYL)ACETIC ACID | 394735-65-0 | MFCD28501990 | 0.25g
AstaTech | (S)-2-((TERT-BUTOXYCARBONYL)AMINO)-2-(4,4-DIFLUOROCYCLOHEXYL)ACETIC ACID | 0.25g | 454129214 | P14953 | 95.000 | 394735-65-0 | MFCD28501990 | 293.311 | C13H21F2NO4
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eMolecules (R)-1-N-CBZ-2-CHLOROMETHYL-PYRROLIDINE | 1187932-05-3 | | 1g
AstaTech | (R)-1-N-CBZ-2-CHLOROMETHYL-PYRROLIDINE | 1g | 112528568 | 64669 | 97.000 | 1187932-05-3 | | 253.730 | C13H16ClNO2
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MEDCHEMEXPRESS LLC GRAZOPREVIR 5MG
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501873180 GRAZOPREVIR 5MG
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Apexbio Technology LLC CYTOCHALASIN D 5MG
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CYTOCHALASIN D 5MG APEXBIO TECHNOLOGIES
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Medchemexpress LLC Bisindolylmaleimide I hydrochloride | 176504-36-2 | MFCD00236429 | 98.4% | 448.94 | C25H25ClN4O2 | 5 MG
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Bisindolylmaleimide I hydrochloride is a cell-permeable, reversible protein kinase C (PKC) inhibitor that also shows activity against GSK-3. It is supplied as a powder for research and analytical use, with reported potency in the low nanomolar range against PKC isoforms and a high reported purity.
- Cell-permeable, reversible PKC inhibitor
- Potent activity: IC50 ≈ 16-20 nM for PKC isoforms
- Also reported to inhibit GSK-3
- High purity (reported 98.4%)
- Supplied as a powder in small analytical pack sizes (for example, 1 mg, 5 mg, 10 mg)
- Recommended storage: powder at 4°C or -20°C; solutions at -20°C or -80°C
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New England Biolabs, Inc. NEBridge Ligase MM - 250 rxn
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NEBridge Ligase Master Mix is a 3X master mix for Golden Gate Assembly. Designed for use with NEB Type IIS restriction enzymes, this master mix contains T4 DNA Ligase in an optimized reaction buffer with a proprietary ligation enhancer. Users need only choose their preferred NEB Type IIS restriction enzyme and add DNA substrates to be assembled. Low complexity single fragment insertions, as well as moderate complexity (3-6 fragment) and high complexity (7-25 fragment) assemblies, are all supported with this optimized reagent and accompanying protocols.
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eMolecules (S)-1-BOC-3-(2-CBZ-AMINO-2-METHOXYCARBONYL-ETHYL)PIPERIDINE | 1217521-20-4 | MFCD09991628 | 1g
AstaTech | (S)-1-BOC-3-(2-CBZ-AMINO-2-METHOXYCARBONYL-ETHYL)PIPERIDINE | 1g | 112524566 | 56550 | 97.000 | 1217521-20-4 | MFCD09991628 | 420.506 | C22H32N2O6
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eMolecules 1-CBZ-2-AMINOMETHYL-PIPERIDINE HCL | 1159826-44-4 | MFCD11101347 | 25g
AstaTech | 1-CBZ-2-AMINOMETHYL-PIPERIDINE HCL | 25g | 222803326 | 56058 | 97.000 | 1159826-44-4 | MFCD11101347 | 284.780 | C14H21ClN2O2
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Medchemexpress LLC Z-LLY-FMK | 133410-84-1 | 98.7% | 557.65 g/mol | C30H40FN3O6 | 5 MG
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Z-LLY-FMK (Calpain Inhibitor IV) is a cell-permeable, irreversible peptide-based inhibitor of calpain proteases used in research to investigate apoptosis and parasite infection models. It is supplied as a solid powder with high reported purity and characterized chemical properties for laboratory use.
- Irreversible inhibitor of calpain proteases, useful for apoptosis studies.
- Cell-permeable peptide suitable for in vitro and in vivo research.
- High purity (~98.7%) for reliable experimental results.
- White to off-white solid with good solubility in common organic solvents.
- Stability information provided for powder and solution storage.
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Apexbio Technology LLC SU 9516 377090-84-1 50mg
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SU 9516 (CAS 377090-84-1) is a potent and selective inhibitor of cyclin-dependent kinase 2 (CDK2) with an IC50 of 22 nM It exhibits markedly reduced activity against CDK1 CDK4 PKC p38 and PDGFR SU 9516 disrupts cell cycle progression by inhibiting CDK2-mediated phosphorylation of the retinoblastoma protein (pRb) and induces cell cycle arrest and apoptosis in various cancer cell lines including colon carcinoma and leukemia It has been shown to reduce levels of Cyclin D1 and CDK2 promote mitochondrial translocation of Bax cytochrome c release and activate caspase cascades SU 9516 serves as a valuable chemical probe for investigating CDK2 function and cell cycle regulation in cancer research
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Medchemexpress LLC (Rac)-Salvianic acid A sodium ((rac)-Danshensu sodium) | 67920-52-9 | 98.0% | 220.15 | 200 MG
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(Rac)-Salvianic acid A sodium is the racemic form of Salvianic acid A, a phenolic compound known for inducing Nrf2/HO-1 activation and inhibiting the NF-κB pathway. It also activates the mitochondrial antioxidant defense system. This compound demonstrates anti-inflammatory, antioxidant, and anti-apoptotic properties.
- Exhibits anti-inflammatory effects.
- Acts as an antioxidant.
- Demonstrates anti-apoptotic properties.
- Induces Nrf2/HO-1 activation.
- Inhibits the NF-κB pathway.
- Activates the mitochondrial antioxidant defense system.
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TARGETMOL CHEMICALS INC E Z-Zotiraciclib 10MG
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Also available in 1 mL, 1 mg, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. (E/Z)-Zotiraciclib ((E/Z)-TG02) effectively inhibits CDK2, JAK2, and FLT3 with IC50s of 13 nM, 73 nM, and 56 nM, respectively. Purity 99.12%
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