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Filtered Search Results
Medchemexpress LLC HY-108630 5mg Medchemexpress, U-73343 CAS:142878-12-4 Purity:>98%
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Medchemexpress, HY-108630 5mg U-73343 CAS:142878-12-4 U-73343, an inhibitor of PLC (putative phospholipase C) -dependent processes, is an analog of U-73122 and can be used as a negative control [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000429562 BODIPY-C12 25MG
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eMolecules MALEIMIDE 1G
5000159058 MALEIMIDE 1G
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Medchemexpress LLC rel- 2R 3S -1 2 3 4- 5g | 5G
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rel- 2R 3S -1 2 3 4- 5g | 5G
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Medchemexpress LLC (S,R,S)-AHPC-Boc (VH032-Boc) | 1448189-98-7 | MFCD31692982 | 96.4% | 530.68 g·mol⁻¹ | C27H38N4O5S | 10MG
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(S,R,S)-AHPC-Boc (VH032-Boc) is a small-molecule ligand that binds the von Hippel-Lindau (VHL) E3 ligase and is used as a VHL-recruiting moiety in PROTAC-mediated targeted protein degradation. It is supplied as solid material in multiple package sizes and as a 10 mM solution in DMSO. Molecular formula C27H38N4O5S, molecular weight 530.68 g·mol⁻¹, typical purity 96.4%.
- Functions as a VHL ligand for recruitment of E3 ligase.
- Suitable for PROTAC synthesis and chemical biology studies.
- High purity (96.4%) for research use.
- Available as solid in multiple quantities and as a 10 mM solution in DMSO.
- Molecular formula C27H38N4O5S and molecular weight 530.68 g·mol⁻¹.
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Medchemexpress LLC 2R 3S-E1R 50mg | 1424832-60-9 | 232.28 g/mol | C13H16N2O2 | 50 MG
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(2R,3S)-E1R is the (2R,3S) enantiomer of E1R and functions as a sigma-1 receptor positive allosteric modulator (Sig1R PAM) for preclinical research into cognition and memory disorders. Supplied as a powder for laboratory use (CAS 1424832-60-9; C13H16N2O2; MW 232.28 g/mol). For research use only.
- Solid powder, light yellow.
- CAS number 1424832-60-9.
- Molecular formula C13H16N2O2; molecular weight 232.28 g/mol.
- Storage: powder -20°C (3 years), 4°C (2 years); in solvent -80°C (6 months), -20°C (1 month).
- Reported purity ~98.8% (supplier specification).
- Intended for preclinical research; not for human or clinical use.
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eMolecules Methyl 1-benzyl-5-oxo-3-pyrrolidinecarboxylate | 51535-00-3 | 5G | Purity: 98%
Combi-Blocks | Methyl 1-benzyl-5-oxo-3-pyrrolidinecarboxylate | 5G | 51535-00-3 | MFCD00003196
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Medchemexpress LLC Protac Bcl2 degrader-1 | 2378801-85-3 | 99.8% | 941.84 | C45H45BrN6O10S | 1MG
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PROTAC Bcl2 degrader-1 is a cereblon-based proteolysis targeting chimera (PROTAC) designed to induce ubiquitin-proteasome mediated degradation of antiapoptotic Bcl-2 family proteins. It is intended for cellular research into targeted protein degradation, apoptosis pathways, and mechanism-of-action studies; manufacturer data provide bioactivity, solubility, purity, and storage guidance to support experimental planning.
- Cereblon-based PROTAC that recruits CRBN E3 ligase.
- Induces selective degradation of Bcl-2 and Mcl-1 in cell assays.
- Reported bioactivity: Bcl-2 DC50 3 μM, Bcl-2 IC50 4.94 μM, Mcl-1 IC50 11.81 μM.
- Molecular formula C45H45BrN6O10S and molecular weight 941.84.
- High purity (99.8%) suitable for research use.
- Soluble in DMSO (≈25 mg/mL) and compatible with common in vivo formulations.
- Store at -20°C under inert atmosphere; in solvent store at -80°C for long term.
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![eMolecules Pharmablock / cis-2-[4-(tert-butoxycarbonylamino)cyclohexyl]acetic acid / 50mg / 703157463 / PBLJ0845 / 0.000 / 327156-95-6 / MFCD01862296 / 257.330 / C13H23NO4](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502514812.JPG-250.jpg)
eMolecules Pharmablock / cis-2-[4-(tert-butoxycarbonylamino)cyclohexyl]acetic acid / 50mg / 703157463 / PBLJ0845 / 0.000 / 327156-95-6 / MFCD01862296 / 257.330 / C13H23NO4
Pharmablock / cis-2-[4-(tert-butoxycarbonylamino)cyclohexyl]acetic acid / 50mg / 703157463 / PBLJ0845 / 0.000 / 327156-95-6 / MFCD01862296 / 257.330 / C13H23NO4
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000370781 5-FAM MALEIMIDE 25MG
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Cayman Chemical 3 Z 6 Z 9 Z 12 Z 15 ZOctadeca
A microalgal PUFA; has been used as a chemotaxonomic biomarker for microalgae and dinoflagellates
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Medchemexpress LLC (Rac)-BAY1238097 | 1564268-19-4 | 99.7% | 451.56 | 10 MM 1 ML
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(Rac)-BAY1238097 is a BET inhibitor, with an IC50 of 1.02 μM for BRD4. It is used in cancer research.
- BET inhibitor
- IC50 of 1.02 μM for BRD4
- Used in cancer research
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Cayman Chemical NArachidonyl Maleimide
A potent inhibitor of monoacylglycerol lipase (IC50 = 140 nM in rat cerebellar membranes)
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eMolecules BENZYL 4-((TERT-BUTOXYCARBONYLAMINO)METHYL)BENZOATE | 204199-03-1 | MFCD29067619 | 1g
AstaTech | BENZYL 4-((TERT-BUTOXYCARBONYLAMINO)METHYL)BENZOATE | 1g | 437210041 | A10079 | 95.000 | 204199-03-1 | MFCD29067619 | 341.407 | C20H23NO4
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Apexbio Technology LLC GW311616 hydrochloride 197890-44-1 5mg
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GW311616 hydrochloride (CAS 197890-44-1) is a selective cell-permeable inhibitor of human neutrophil elastase (HNE) exhibiting an IC50 of 22 nM and a Ki of 0 13 nM in enzymatic assays It demonstrates pronounced selectivity with IC50 values exceeding 100 M for trypsin cathepsin G and plasmin and greater than 3 M for chymotrypsin and tissue plasminogen activator In human whole blood assays GW311616 hydrochloride achieves an IC50 of 0 67 M The compound is orally bioavailable and displays prolonged activity in dog blood samples indicating a sustained inhibitory effect on neutrophil elastase GW311616 hydrochloride is valuable for investigating HNE s role in inflammation and related pathologies
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