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Filtered Search Results
Cayman Chemical BIsIndolylmaleImIde IV 25mg
A cell permeable inhibitor of PKC with IC50 values reported to range from 0.10 to 0.55 µM; designed to be more discriminative than its parent compound, the non-selective PKC inhibitor, staurosporine (Item No. 81590); also inhibits protein kinase A with IC50 values ranging from 2 to 11.8 µM
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eMolecules Medchem Express / Bisindolylmaleimide VIII (acetate) / 5mg / 532149886 / HY-129624A / / 138516-31-1 / MFCD00909467 / 458.518 / C26H26N4O4
Medchem Express / Bisindolylmaleimide VIII (acetate) / 5mg / 532149886 / HY-129624A / / 138516-31-1 / MFCD00909467 / 458.518 / C26H26N4O4
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MEDCHEMEXPRESS LLC GO 6983 5MG
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501872939 GO 6983 5MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000383839 AZIDO-PEG11-AZIDE 50MG
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![eMolecules Broadpharm / Sulfo-Cy7 maleimide / 5mg / 374905261 / BP-23928 / 95.000 / 2183440-60-8 / [null] / 869.100 / C43H49KN4O9S2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502513201.JPG-250.jpg)
eMolecules Broadpharm / Sulfo-Cy7 maleimide / 5mg / 374905261 / BP-23928 / 95.000 / 2183440-60-8 / [null] / 869.100 / C43H49KN4O9S2
Broadpharm / Sulfo-Cy7 maleimide / 5mg / 374905261 / BP-23928 / 95.000 / 2183440-60-8 / [null] / 869.100 / C43H49KN4O9S2
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Medchemexpress LLC GSK-872 | 1346546-69-7 | MFCD30481302 | 99.8% | 383.49 g/mol | C19H17N3O2S2 | 25 MG
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GSK-872 is a potent, selective small-molecule inhibitor of receptor-interacting protein kinase 3 (RIPK3) used in research to probe necroptosis and RIPK3-dependent signaling. It binds the RIP3 kinase domain at low nanomolar concentrations and is supplied as a solid powder for laboratory use.
- Binds RIP3 kinase domain with IC50 approximately 1.8 nM and inhibits kinase activity (IC50 approximately 1.3 nM).
- High biochemical selectivity for RIPK3 versus other kinases.
- Useful tool compound for necroptosis and cell-death pathway studies.
- Provided as a powder suitable for preparing stock solutions in common solvents.
- Molecular formula C19H17N3O2S2 and molecular weight 383.49 g/mol.
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Medchemexpress LLC BMS-1166 (hydrochloride) | 2113650-05-6 | 100.0% | 677.57 g/mol | C36H34Cl2N2O7 | 5 MG
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BMS-1166 hydrochloride is a small-molecule PD-1/PD-L1 immune checkpoint inhibitor that induces PD-L1 dimerization and blocks PD-1 binding. It exhibits potent biochemical activity in the low-nanomolar range and is supplied as a stable hydrochloride salt in solid form for research use in biochemical and cellular assays.
- Potent PD-1/PD-L1 interaction inhibitor with low-nanomolar activity.
- Hydrochloride salt, solid, white to off-white, suitable for handling.
- High purity appropriate for research applications.
- Stable as a powder under recommended storage conditions for extended shelf life.
- Intended for use in biochemical and cell-based immune checkpoint studies.
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Medchemexpress LLC Cbz-NH-PEG4-C2-acid | 756526-00-8 | MFCD11041139 | 95.0% | 399.44 g/mol | C19H29NO8 | 250 MG
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Cbz-NH-PEG4-C2-acid is a PEG-based linker designed for PROTAC synthesis. It features a Cbz-protected amino group and a terminal carboxylic acid separated by a four-unit ethylene glycol spacer, providing solubility and flexibility for conjugation. The compound is intended for use in medicinal chemistry to connect ligands and enable targeted protein degrader construction.
- Cbz-protected amino group for selective deprotection
- Terminal carboxylic acid enables standard amide-coupling chemistries
- PEG4 spacer imparts flexibility and improves solubility
- Suitable for PROTAC linker construction and linker optimization studies
- Available in common laboratory pack sizes for synthesis workflows
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Medchemexpress LLC 4-phenyl-2-pyrrolidinone | 1198-97-6 | MFCD01687226 | >98.0% | 161.20 g/mol | C10H11NO | 5 G
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4-Phenyl-2-pyrrolidinone (CAS 1198-97-6) is a small-molecule synthetic intermediate and precursor used in organic synthesis and medicinal chemistry research. It is supplied as a solid for research and development applications and is reported in literature as an intermediate in the synthesis of anticonvulsant and nootropic compounds.
- High purity (≥98.0%) as stated on certificate of analysis.
- White to off-white solid appearance.
- Molecular formula C10H11NO; molecular weight 161.20 g/mol.
- Suitable as a precursor and synthetic intermediate in medicinal chemistry.
- Packaged for small-scale research use.
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Medchemexpress LLC 3'-azido-2',3'-dideoxyuridine | 84472-85-5 | 99.1% | 253.21 | C9H11N5O4 | 5 MG
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3'-Azido-2',3'-dideoxyuridine is a nucleoside analog research reagent that inhibits human immunodeficiency virus (HIV) replication in peripheral blood mononuclear cells (PBMC). It contains an azide functional group that enables copper-catalyzed or strain-promoted azide-alkyne cycloaddition for bioconjugation and labeling in chemical biology and antiviral research.
- Inhibits HIV replication in PBMC assays.
- Contains an azide group for copper-catalyzed and strain-promoted click chemistry (CuAAC, SPAAC).
- High chemical purity suitable for analytical and biological studies.
- Supplied in small milligram quantities for research use.
- Applicable in antiviral mechanism studies and bioconjugation workflows.
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Medchemexpress LLC Protac ERRα degrader-3 | 2306388-65-6 | 98.8% | C47H50F6N6O7S | 10MG
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PROTAC ERRα Degrader-3 is a proteolysis-targeting chimera (PROTAC) that selectively induces degradation of estrogen-related receptor alpha (ERRα). It is built on a von Hippel-Lindau (VHL) E3 ligase ligand and is reported to degrade ERRα by more than 80% at 30 nM while showing no activity against ERRβ or ERRγ.
- Selective degradation of ERRα (>80% at 30 nM).
- Inactive against ERRβ and ERRγ, supporting target specificity.
- VHL-based E3 ligase recruitment mechanism.
- High chemical purity (≈98.8%).
- Molecular formula C47H50F6N6O7S; molecular weight 956.99.
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Medchemexpress LLC (Rac)-IBT6A | 1412418-47-3 | 98.2% | C22H22N6O | 10MG
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A racemic form of IBT6A, this small-molecule impurity of the BTK inhibitor ibrutinib is supplied for research use as a synthetic intermediate and analytical reference. The solid is characterized by molecular formula C22H22N6O and molecular weight 386.45 g·mol⁻¹, with batch COA confirming typical purity of 98.18% by LCMS.
- racemic small-molecule impurity useful for synthetic chemistry
- suitable as an analytical reference or impurity standard
- characterized by LCMS with typical purity of 98.2%
- provided as a solid, white to off-white appearance
- available in milligram-scale quantities for research applications
- molecular formula C22H22N6O and molecular weight 386.45 g·mol⁻¹
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eMolecules 1-TERT-BUTOXYCARBONYL-3-I 5G
5000188320 1-TERT-BUTOXYCARBONYL-3-I 5G
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Medchemexpress LLC (Z)-4-hydroxy tamoxifen-d5 | 164365-20-2 | MFCD07369456 | 98.3% | C26H24D5NO2 | 10MG
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(Z)-4-Hydroxy Tamoxifen-d5 is the deuterium-labeled (d5) analogue of (Z)-4-hydroxy tamoxifen provided as a high-purity analytical reagent for research use. It is intended for use as an internal standard, tracer, or analytical reference in quantitative mass spectrometry, metabolite profiling, and pharmacokinetic studies; handle and store according to recommended conditions to maintain stability.
- Deuterium-labeled (d5) isotopologue for mass spectrometry applications.
- High purity (98.3%) for reliable analytical performance.
- Suitable as an internal standard or tracer in quantitative assays.
- Chemical formula C26H24D5NO2; CAS 164365-20-2.
- Available in small laboratory pack sizes for analytical workflows.
- Recommended storage: powder at -20°C (long-term) or 4°C (short-term); in solvent at -80°C.
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eMolecules S-1-BOC-3-HYDROXYMETHYL 25G
5000189151 S-1-BOC-3-HYDROXYMETHYL 25G
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