Pyrrolidines

Medchemexpress LLC (Rac)-minzasolmin | 1802518-63-3 | 99.9% | 425.59 | C23H31N5OS | 5MG

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(Rac)-Minzasolmin is a racemic small-molecule inhibitor of α-synuclein misfolding with oral bioavailability and blood-brain barrier penetration. It modulates early-stage α-synuclein aggregation and is used in preclinical in vitro and in vivo studies to reduce pathological α-synuclein accumulation in models of Parkinson's disease and related synucleinopathies.

• High purity, typically reported as 99.9%.
• Blood-brain barrier permeable small molecule.
• Racemic composition for preclinical comparison of enantiomeric activity.
• Molecular formula C23H31N5OS and molecular weight 425.59 g·mol⁻¹.
• Suitable for both in vitro assays and in vivo model studies.

Medchemexpress LLC (Rac)-minzasolmin | 1802518-63-3 | 99.9% | 425.59 g/mol | C23H31N5OS | 10MG

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(Rac)-Minzasolmin is a racemic, brain-penetrant inhibitor of α-synuclein misfolding developed for research into synucleinopathies. It modulates early-stage aggregation, can revert membrane-bound oligomers to monomers, and has shown efficacy in α-synuclein transgenic models relevant to Parkinson's disease and dementia with Lewy bodies.

• Brain-penetrant small molecule suitable for in vivo and in vitro studies.
• Inhibits α-synuclein misfolding and early-stage aggregation.
• Promotes reversion of membrane-bound oligomers to monomers.
• Demonstrated activity in α-synuclein transgenic models.
• High purity for research use (≈99.9%).
• Molecular formula C23H31N5OS; molecular weight 425.59 g/mol.

Medchemexpress LLC Propanoic acid, 3-[2-(2-azidoethoxy)ethoxy]- | 1312309-63-9 | 99.88% | C7H13N3O4 | 250 MG

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Azido-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is a click chemistry reagent containing an Azide group, capable of undergoing copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with Alkyne groups and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.

• PEG-based PROTAC linker
• Click chemistry reagent
• Contains an Azide group
• Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc)
• Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions

Medchemexpress LLC N-(1-(1H-indol-3-yl)hexan-2-yl)-2-(4-methylpiperazin-1-yl)-1,3-thiazole-5-carboxamide (racemic) | 1802518-63-3 | 99.9% | 425.59 g·mol⁻¹ | C23H31N5OS | 25MG

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(Rac)-Minzasolmin is a racemic small-molecule inhibitor of alpha-synuclein misfolding that penetrates the blood-brain barrier. It acts on early-stage aggregation by displacing membrane-bound oligomers, promoting reversion to monomers and reducing pathological aggregation. It is used in preclinical research to evaluate effects on alpha-synuclein deposition and neuro-pathological markers in models of Parkinson's disease and dementia with Lewy bodies.

• Racemic small-molecule inhibitor of alpha-synuclein misfolding.
• Blood-brain barrier penetrant for central nervous system studies.
• Modulates early-stage alpha-synuclein aggregation mechanisms.
• Shown to reduce alpha-synuclein deposition in preclinical models.
• Supplied as a solid with high chemical purity for laboratory use.
• Available in small-scale quantities suitable for preclinical experiments.

Strem, An Ascensus Company CAS 1357562-63-0. 50mg. 1-(2S)-1-[(11bS)-26-Dimethyldinaphtho[21-d12-f][132]dioxaphosphepin-4-yloxy]propan-2-yl-3-phenylurea min. 97%. MFCD18827630

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CAS 1357562-63-0. 50mg. 1-(2S)-1-[(11bS)-26-Dimethyldinaphtho[21-d12-f][132]dioxaphosphepin-4-yloxy]propan-2-yl-3-phenylurea min. 97%. MFCD18827630. Molecular Weight 536.56. Molecular Formula C32H29N2O4P. Color/form white pwdr. Strem 15-2204. http//www.strem.com/catalog/v/15-2204/

STA PHARMACEUTICAL US LLC DNA C(Bz) amidite | 1 g | CAS 102212-98-6 | MDL MFCD00036315

DNA C(Bz) amidite is a Amidite reagent (Subcategory: Cytosine Series) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. SDS available for reference.

Specifications
- CAS: 102212-98-6
- MDL: MFCD00036315
- InChIKey: PGTNFMKLGRFZDX-SALLYJDFSA-N
- Molecular Weight: 833.922761998
- Molecular Formula: C46H52N5O8P
- Purity: ≥99%
- Container Type: 60 mL Glass (20-400)
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 63 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3S,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1C[C@H](N2C(N=C(C=C2)NC(C3=CC=CC=C3)=O)=O)O[C@@H]1COC(C4=CC=C(C=C4)OC)(C5=CC=C(C=C5)OC)C6=CC=CC=C6)OCCC#N)C(C)C)C