Pyrrolidines

Medchemexpress LLC (Z)-Ono 1301 | 153814-74-5 | 98.1% | 428.48 g/mol | C26H24N2O4 | 5 MG

(Z)-ONO 1301 is the Z geometric isomer of the prostacyclin agonist ONO-1301, provided as a research reagent for use as an experimental control in studies of prostacyclin signaling and thromboxane synthase inhibition. The compound is supplied as a solid and characterized by COA/SDS data including molecular formula, molecular weight, and HPLC purity.

• Used as an experimental control isomer in prostacyclin-related studies.
• High purity, 98.1% by HPLC.
• Molecular weight 428.48 g/mol.
• Chemical formula C26H24N2O4.
• Off-white to light yellow solid appearance.
• Recommended storage: powder at -20°C; in solvent at -80°C.

Medchemexpress LLC (S,R,S)-AHPC | 1448297-52-6 | MFCD29049827 | 99.1% | 430.56 g/mol | C22H30N4O3S | 100MG

(S,R,S)-AHPC is a VH032-derived VHL ligand used to recruit the von Hippel-Lindau E3 ligase in PROTAC and targeted protein degradation research. Supplied as a powder for research use, it has CAS 1448297-52-6, chemical formula C22H30N4O3S, molecular weight 430.56 g/mol, and measured HPLC purity 99.13%.

• Provides high-purity VHL ligand suitable for PROTAC construction.
• Powder form for easy storage and handling.
• Stable under recommended storage conditions (powder: -20°C/4°C; in solvent: -80°C/-20°C).
• Soluble in DMSO and water with ultrasonic assistance for formulation.
• Available in small research pack sizes for early-stage studies.
• Characterized by HPLC and LCMS to confirm identity and purity.

Medchemexpress LLC Dapagliflozin propanediol hydrate | 960404-48-2 | MFCD28167768 | ≥98.0% | 503.0 g·mol⁻1 | C24H35ClO9 | 1 ML

Dapagliflozin propanediol hydrate is the propanediol monohydrate form of the SGLT2 inhibitor dapagliflozin, provided for research use in cellular and biochemical studies. It is commonly supplied as a concentrated stock solution (example: 10 mM) for in vitro assays, and the hydrate salt aids handling and stability compared with the free compound.

• SGLT2 inhibition mechanism useful for glucose transport and metabolic disease research.
• Ready-to-use stock solution format simplifies preparation for cell-based assays.
• Hydrate salt form enhances stability and solubility in polar solvents.
• High analytical purity suitable for biochemical and pharmacology experiments (≥98.0% HPLC).
• Compatible with common in vitro assay workflows and low-temperature storage.

Medchemexpress LLC Ruboxistaurin (LY-333531) | 169939-94-0 | 99.5% | 468.5 g/mol | C28H28N4O3 | 10 MG

Ruboxistaurin (LY-333531) is a small-molecule, orally active, selective protein kinase C beta (PKCβ) inhibitor supplied for research use. It is intended for use in biochemical and cell-based studies to probe PKCβ-dependent signaling and exhibits low-nanomolar potency (Ki ≈ 2 nM; IC50 PKCβ1 ≈ 4.7 nM, PKCβ2 ≈ 5.9 nM). Provided as a measured solid for laboratory research; not for human or clinical use.

• Selective inhibition of protein kinase C beta with low-nanomolar potency.
• High purity as supplied (HPLC: 99.48%).
• Suitable for biochemical and cell-based assays.
• Available in small measured quantities for research use.
• Soluble in common organic solvents for assay preparation.

Medchemexpress LLC Dapagliflozin ((2S)-1,2-propanediol, hydrate) | 960404-48-2 | 100.0% | 502.98 | C24H35ClO9 | 100 MG

Dapagliflozin ((2S)-1,2-propanediol, hydrate) is the propanediol monohydrate form of a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor supplied as a solid for research and analytical use in diabetes and metabolic studies. The material is analytically characterized and provided in laboratory-scale pack sizes for experimental workflows.

• Selective SGLT2 inhibitor for metabolic and diabetes research.
• High purity by HPLC (99.99%).
• Appearance: white to off-white solid.
• Supplied in convenient laboratory pack sizes including 100 MG.
• Analytical identity confirmed by 1H NMR and LCMS.
• Store sealed, away from moisture; in solvent store at -80°C (up to 2 years) or -20°C (up to 1 year).