Quinolines and derivatives
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Filtered Search Results
Medchemexpress LLC Ethanamine, 2-(2-azidoethoxy)- | 464190-91-8 | ≥98.0% | C4H10N4O | 250 MG
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Azido-PEG1-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Click chemistry reagent
- Contains an azide group
- Reacts via copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Reacts via strain-promoted alkyne-azide cycloaddition (SPAAC)
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Medchemexpress LLC Amino-PEG7-amine | 332941-25-0 | 99.3% | C16H36N2O7 | 250 MG
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Amino-PEG7-amine is a PEG-based PROTAC linker used in the synthesis of Proteolysis Targeting Chimeras (PROTACs). These compounds are designed with two ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other for a target protein. PROTACs utilize the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins. This product is for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Utilizes the intracellular ubiquitin-proteasome system
- Designed for selective degradation of target proteins
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Ambeed Pyrazine2carbaldehyde
Pyrazine-2-carbaldehyde, 5780-66-5, 95%
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Medchemexpress LLC SULFO-SPP 1MG
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5000202014 SULFO-SPP 1MG
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Medchemexpress LLC m-PEG7-amine | 170572-38-0 | MFCD13184965 | 98.0% | 339.43 g/mol | C15H33NO7 | 5 G
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m-PEG7-Amine is a methoxy-terminated polyethylene glycol (PEG) linker bearing a terminal primary amine. It is used as a PROTAC linker and as a cleavable ADC linker for antibody-drug conjugation and other bioconjugation applications. The reagent provides a flexible, hydrophilic spacer suitable for linker chemistry in targeted degraders and conjugates.
- Methoxy-terminated PEG with seven ethylene glycol units.
- Terminal primary amine for facile coupling to carboxylates and activated esters.
- Molecular weight 339.43 g/mol and CAS 170572-38-0.
- Suitable for use as a PROTAC linker and a cleavable ADC linker.
- Hydrophilic spacer that improves solubility and reduces aggregation in conjugates.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000292831 IL-31 PROTEIN MOUSE 10UG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000783113 1 7-DIBROMOHEPTANE 25G
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Ambeed 1R 2R Cyclohexane1 2diamine
(1R,2R)-Cyclohexane-1,2-diamine, 20439-47-8, 96%
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![eMolecules 2089251-33-0 | 1-Octylnonyl 8-[(2-hydroxyethyl)[8-(nonyloxy)-8-oxooctyl]amino]octanoate | Acrotein ChemBio Inc.710.182 | C44H87NO5 | 97.000 | CCCCCCCCCOC(=O)CCCCCCCN(CCO)CCCCCCCC(=O)OC(CCCCCCCC)CCCCCCCC | 1g | 825286052](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC3942582.jpg-250.jpg)
eMolecules 2089251-33-0 | 1-Octylnonyl 8-[(2-hydroxyethyl)[8-(nonyloxy)-8-oxooctyl]amino]octanoate | Acrotein ChemBio Inc.710.182 | C44H87NO5 | 97.000 | CCCCCCCCCOC(=O)CCCCCCCN(CCO)CCCCCCCC(=O)OC(CCCCCCCC)CCCCCCCC | 1g | 825286052
1-Octylnonyl 8-[(2-hydroxyethyl)[8-(nonyloxy)-8-oxooctyl]amino]octanoate | Acrotein ChemBio Inc. | 2089251-33-0710.182 | C44H87NO5 | 97.000 | CCCCCCCCCOC(=O)CCCCCCCN(CCO)CCCCCCCC(=O)OC(CCCCCCCC)CCCCCCCC | 1g | 825286052
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000770639 3 6-DINITRO-9H-CARBA 500MG
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Ambeed Mono 6amino6deoxy cyclodextri
Mono-(6-amino-6-deoxy)-β-cyclodextrin, 29390-67-8, 95%
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Medchemexpress LLC SCH772984 | 942183-80-4 | 99.8% | C33H33N9O2 | 200 MG
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SCH772984 is a highly selective and ATP-competitive ERK inhibitor, with IC50s of 4 nM for ERK1 and 1 nM for ERK2. It exhibits antitumor activity in both MAPK inhibitor-naive and MAPK inhibitor-resistant cells that contain BRAF or RAS mutations.
- Highly selective and ATP-competitive ERK inhibitor
- Exhibits antitumor activity in MAPK inhibitor-naive and resistant cells
- Induces G1 arrest and apoptosis in sensitive melanoma cells
- Inhibits ERK and RSK phosphorylation
- Shows EC50 values less than 500 nM in BRAF-mutant and RAS-mutant tumor lines
- Leads to significant tumor regression in animal models
- Well tolerated in vivo
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Ambeed 2Chloro9Hpurine
2-Chloro-9H-purine, 1681-15-8, 97%
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Medchemexpress LLC TCO-PEG3-amine | 1800507-93-0 | 96.5% | C17H32N2O5 | 50 MG
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TCO-PEG3-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Can be used as an E3 ubiquitin ligase inhibitor
- Used in protein degradation studies
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Medchemexpress LLC Nintedanib esylate | 656247-18-6 | 649.76 | 50 MG
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Nintedanib esylate | 656247-18-6 | 649.76 | 50 MG
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