Quinolines and derivatives
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Filtered Search Results
Medchemexpress LLC Amino-PEG7-amine | 332941-25-0 | 99.3% | C16H36N2O7 | 100 MG
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Amino-PEG7-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This mechanism allows PROTACs to exploit the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. It is intended for research use only.
- Utilized in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Intended for research use only
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Medchemexpress LLC Azido-PEG8-amine | 857891-82-8 | 99.9% | C18H38N4O8 | 50MG
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Azido-PEG8-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. This click chemistry reagent contains an Azide group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with Alkyne group molecules. It can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an Azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc)
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
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Medchemexpress LLC Azido-PEG10-amine | 912849-73-1 | 97.0% | C22H46N4O10 | 100 MG
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Azido-PEG10-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group. This allows it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups, and also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Utilized in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an azide group for CuAAc and SPAAC reactions
- Enables reactions with alkyne, DBCO, or BCN groups
- Leverages the ubiquitin-proteasome system to selectively degrade target proteins
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Medchemexpress LLC DBCO-amine | 1255942-06-3 | 99.1% | 276.34 g·mol-1 | C18H16N2O | 25 MG
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DBCO-amine is a dibenzocyclooctyne-containing amine reagent used for strain-promoted alkyne-azide cycloaddition (SPAAC) click chemistry. It is used as a small linker for bioconjugation and the synthesis of antibody-drug conjugates, and is typically handled and stored under anhydrous conditions and in organic solvent solutions for formulation.
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC) bioconjugation.
- High purity suitable for synthetic and bioconjugation applications.
- Minimal spacer length reduces steric hindrance in conjugates.
- Compatible with common coupling chemistries for linker installation.
- Soluble in DMSO for straightforward formulation and handling.
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Medchemexpress LLC mPEG-amine (MW 1000) | 80506-64-5 | 99.2% | (C2H4O)nC3H9NO | 500 MG
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mPEG-amine (MW 1000) is a PEG-based PROTAC linker designed for the synthesis of PROTACs. PROTACs are compounds that connect an E3 ubiquitin ligase ligand with a target protein ligand via a linker. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used for the synthesis of PROTACs
- Utilizes ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC m-PEG8-amine | 869718-81-0 | MFCD13184961 | ≥98.0% | 383.48 g·mol⁻¹ | C17H37NO8 | 100 MG
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m-PEG8-amine is an 8-unit monomethoxy polyethylene glycol (PEG) bearing a terminal primary amine used as a cleavable spacer/linker in antibody-drug conjugates and for general bioconjugation. It is supplied as a powder and is typically handled and stored according to the supplier's safety documentation.
- Chemical name: m-PEG8-amine
- Cas number: 869718-81-0
- Purity: ≥98.0%
- Molecular formula: C17H37NO8
- Molecular weight: 383.48 g·mol⁻¹
- Typical solubility: soluble in DMSO
- Available pack sizes: 50 MG, 100 MG, 500 MG, 1 G, 5 G, 10 G, 50 G
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Medchemexpress LLC Benzyl-PEG5-amine | 86770-77-6 | 98.0% | C17H29NO5 | 50 MG
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Benzyl-PEG5-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are designed with two distinct ligands connected by a linker; one targets an E3 ubiquitin ligase, and the other targets a specific protein. This mechanism leverages the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- Peg-based protac linker
- Used in the synthesis of protacs
- Utilizes ubiquitin-proteasome system
- Selectively degrades target proteins
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eMolecules Synthonix Methyl 2-(quinolin-6-yl)acetate 100mg 649427513 M38116 0 000 5622-36-6 MFCD04038669 201 225 C12H11NO2
Synthonix Methyl 2-(quinolin-6-yl)acetate 100mg 649427513 M38116 0 000 5622-36-6 MFCD04038669 201 225 C12H11NO2
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Cayman Chemical 8 12isoiPF2aVI1 5lactone
A racemic mixture of the lactone form of the free acid, 8,12-iso- iPF2α-VI; the free acid is the most abundant F2-iP2 regioisomer measured in the urine of rats treated to induce lipid peroxidation; used as a biomarker for oxidative stress
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Ambeed 2Bromo1 10phenanthroline
2-Bromo-1,10-phenanthroline, 22426-14-8, 97%
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Cayman Chemical 8 12isoiPF2aVId11
An internal standard for the quantification of 8,12-iso-iPF2α-VI by GC- or LC-MS.
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eMolecules 3-AMINOISOQUINOLINE-8-CARBOXYLIC ACID HCL | 1337882-40-2 | MFCD28291832 | 1g
AstaTech | 3-AMINOISOQUINOLINE-8-CARBOXYLIC ACID HCL | 1g | 200614905 | 68507 | 95.000 | 1337882-40-2 | MFCD28291832 | 224.640 | C10H9ClN2O2
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Ambeed Dicyclohexyl 3isopropoxy2 4
Dicyclohexyl(3-isopropoxy-2',4',6'-triisopropyl-[1,1'-biphenyl]-2-yl)phosphine, 2118959-55-8, 97%
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Medchemexpress LLC Benzyl-PEG7-amine 5mg
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Benzyl-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
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Ambeed 4 6 2 3Methylbenzylidene hydra
4-(6-(2-(3-Methylbenzylidene)hydrazinyl)-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl)morpholine dimethanesulfonate, 870087-36-8, 98%
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