Quinolines and derivatives
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Filtered Search Results
Accela Chembio Inc 6-hydroxy-3 | 4-dihydro-2(1h)-quinolinone | 100g | 54197-66-9 | MFCD02179410 | 97+% | Shelf Life: 2160 Days | Regular
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6-hydroxy-3 | 4-dihydro-2(1h)-quinolinone | 100g | 54197-66-9 | MFCD02179410 | 97+% | Shelf Life: 2160 Days | Regular
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Chem-Impex International, Inc. 7-Hydroxy-3,4-Dihydro-2(1H)-quinolinone | 22246-18-0 | MFCD06410891 | 5G
7-Hydroxy-3,4-Dihydro-2(1H)-quinolinone, 22246-18-0, MFCD06410891, 5G
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Apexbio Technology LLC HyperTrap Q HP Column 5x1ml
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HyperTrap Q HP Column is not a small molecule but a high-performance chromatography column designed for biomolecule purification Featuring a strong anion exchange resin with quaternary ammonium functional groups the column enables efficient separation and capture of negatively charged biomolecules such as proteins and nucleic acids based on their charge properties The column supports high binding capacity and robust performance across a range of pH conditions making it suitable for process development scale-up and routine purification workflows in biomedical research particularly for the preparation and analysis of protein therapeutics and other biologically relevant molecules
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Chemscene CHEMSCENE
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5000577303 ETHYL 2-METHYLQUINOLINE-3- 10G
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Medchemexpress LLC BSJ-03-204 | 2349356-09-6 | 99.8% | 832.90 | 25 MG
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BSJ-03-204 is a PROTAC that connects ligands for Cereblon and CDK. It is a potent and selective Palbociclib-based CDK4/6 dual degrader (PROTAC), with IC50s of 26.9 nM for CDK4/D1 and 10.4 nM for CDK6/D1. This compound does not induce IKZF1/3 degradation and exhibits anti-cancer activity.
- Potent and selective CDK4/6 dual degrader
- Does not cause IKZF1/3 degradation
- Demonstrates anti-cancer activity
- Potent anti-proliferative effects on MCL cell lines
- Induces G1 arrest
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Ambeed 4 4 Bipyridine
4,4'-Bipyridine, 553-26-4, 98%
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Ambeed Methyl 4bromo3methylbenzoate
Methyl 4-bromo-3-methylbenzoate, 148547-19-7, 98%
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Ambeed 1HImidazole2carbaldehyde
1H-Imidazole-2-carbaldehyde, 10111-08-7, 95%
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Medchemexpress LLC KRAS G12D-IN-31 | 3024060-23-6 | 98.5% | 698.80 | 1 MG
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KRAS G12D-IN-31 is a potent inhibitor of KRAS G12D, demonstrating an IC50 of less than 100 nM. It effectively inhibits the proliferation of various RAS-dependent cells, including those with KRASG12C, KRAS G12D, KRASG12V, and KRASWT mutations. This compound is a valuable tool for research into conditions such as non-small cell lung cancer, gastric cancer, colon cancer, and malignant melanoma.
- Potent KRAS G12D inhibitor
- Inhibits proliferation of RAS-dependent cells
- Suitable for research on non-small cell lung cancer
- Suitable for research on gastric cancer
- Suitable for research on colon cancer
- Suitable for research on malignant melanoma
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Medchemexpress LLC Pomalidomide-amido-C1-Br | 2351106-38-0 | MFCD32903493 | >98.0% | C15H12BrN3O5 | 10MG
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Pomalidomide-amido-C1-Br is an E3 ligase ligand-linker conjugate that incorporates a pomalidomide-based cereblon ligand for use in targeted protein degradation and PROTAC research. The compound is supplied as a high-purity research reagent (CAS 2351106-38-0) with molecular formula C15H12BrN3O5 and molecular weight 394.18 g·mol⁻¹. It is typically provided in milligram-scale quantities for screening and synthetic applications.
- High purity suitable for biochemical research.
- Contains a pomalidomide-based cereblon ligand for PROTAC design.
- Provided in small milligram-scale pack sizes for screening and synthesis.
- Characterized by molecular formula and molecular weight for identity confirmation.
- Supports design and development of E3 ligase recruiting degraders.
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Ambeed tertButyl 1 8diazaspiro 4.5 de
tert-Butyl 1,8-diazaspiro[4.5]decane-8-carboxylate, 937729-06-1, 95%
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Ambeed Methyl 4bromo3methylbenzoate
Methyl 4-bromo-3-methylbenzoate, 148547-19-7, 98%
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Ambeed 1R 2S 1Amino2 3dihydro1Hinden
(1R,2S)-1-Amino-2,3-dihydro-1H-inden-2-ol, 136030-00-7, 98%
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Ambeed 1 1 Biphenyl 4ylboronic acid
[1,1'-Biphenyl]-4-ylboronic acid, 5122-94-1, 98%
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Apexbio Technology LLC R 59-022 93076-89-2 5mg
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R 59-022 (CAS 93076-89-2) is a small molecule inhibitor of diacylglycerol kinase (DGK) demonstrating an IC50 of 2 8 M for DGK activity By inhibiting the conversion of 1-oleoyl-2-acetylglycerol to phosphatidic acid R 59-022 modulates diacylglycerol signaling pathways The compound also exhibits antagonistic effects at serotonin (5-HT) receptors and can induce activation of protein kinase C (PKC) In cellular studies R 59-022 enhances thrombin-induced diacylglycerol accumulation in platelets and suppresses phosphatidic acid formation in neutrophils It serves as a valuable tool for investigating DGK-mediated processes and signal transduction mechanisms
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