Quinolines and derivatives
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Filtered Search Results
Medchemexpress LLC Amino-PEG12-amine | 361543-12-6 | HY-133327 | 99.9% | 588.73 | 250 MG
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Amino-PEG12-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are molecules with two different ligands connected by a linker: one for an E3 ubiquitin ligase and another for a target protein. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used as a PEG-based PROTAC linker
- Enables synthesis of PROTACs
- Facilitates selective degradation of target proteins
- Appears as a colorless to off-white solid-liquid mixture
- Has a purity of 99.92%
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eMolecules 101066-61-9 | 2-chloropyridine-4-carbaldehyde | Pharmablock | MFCD06651557 | 141.550 | C6H4ClNO | 97.000 | Clc1cc(C=O)ccn1 | 2.5g | 686925096
2-chloropyridine-4-carbaldehyde | Pharmablock | 101066-61-9 | MFCD06651557 | 141.550 | C6H4ClNO | 97.000 | Clc1cc(C=O)ccn1 | 2.5g | 686925096
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Selleck Chemical LLC Quinoline-4-carboxylic acid
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Quinoline-4-carboxylic acid (4-Carboxyquinoline) is a very important structure in a synthetic medicinal chemistry
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Medchemexpress LLC TL02-59 | 1315330-17-6 | 99.9% | 609.64 | 50 MG
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TL02-59 is an orally active, selective Src-family kinase Fgr inhibitor with an IC50 of 0.03 nM. It also inhibits Lyn and Hck with IC50s of 0.1 nM and 160 nM, respectively. This compound potently suppresses acute myelogenous leukemia (AML) cell growth.
- Selective Src-family kinase Fgr inhibitor with high potency.
- Inhibits Lyn and Hck.
- Potently suppresses acute myelogenous leukemia (AML) cell growth.
- Induces growth arrest and apoptosis in AML cell lines.
- Eliminates AML cells from spleen and peripheral blood in mouse models.
- Significantly suppresses bone marrow involvement in mouse models.
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Aobchem AOBCHEM
5000922762 3 4 -BIPYRIDIN -6-AMINE 500MG
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eMolecules 5470-96-2 | 2-Quinolinecarboxaldehyde | Accela ChemBio (ASD) | MFCD00075032 | 157.172 | C10H7NO | 95.000 | O=Cc1ccc2ccccc2n1 | 1g | 524976315
2-Quinolinecarboxaldehyde | Accela ChemBio (ASD) | 5470-96-2 | MFCD00075032 | 157.172 | C10H7NO | 95.000 | O=Cc1ccc2ccccc2n1 | 1g | 524976315
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![Apexbio Technology LLC prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens] 1mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000096894.png-250.jpg)
Apexbio Technology LLC prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens] 1mg
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Prostate apoptosis response protein PAR-4 2-7 is a short peptide targeting transcriptional regulation pathways It is designed to modulate transcription factor activity thereby influencing apoptosis mechanisms particularly in prostate cells PAR-4 2-7 exerts its biological activity primarily through interaction with transcription factors via a leucine zipper zinc finger domain facilitating apoptosis in transformed or malignant cells while sparing normal cells Based on these properties PAR-4 2-7 holds research potential in studies investigating tumor suppression mechanisms and transcription-mediated apoptosis regulation in oncology and therapeutic research
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Aobchem AOBCHEM
5000922865 1- 2-METHYLQUINOLIN-3-YL ETHAN
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Apexbio Technology LLC TAK-438 1260141-27-2 200mg
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TAK-438 is a small-molecule inhibitor targeting gastric H K -ATPase It is designed to reversibly block potassium-competitive activity of this enzyme thereby suppressing gastric acid secretion TAK-438 exerts its biological activity primarily through direct potassium-competitive inhibition of the gastric H K -ATPase enzyme In animal studies TAK-438 demonstrates concentration-dependent inhibition of histamine-stimulated acid secretion in rats and dogs with effects persisting beyond 24 hours after oral administration Based on these pharmacological properties TAK-438 holds research potential in studies involving gastric acid physiology and acid-related gastrointestinal disorders
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Selleck Chemical LLC FLI-06
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FLI-06 is a novel inhibitor of Notch signaling with EC50 of 2 3 M
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Selleck Chemical LLC SH-4-54
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SH-4-54 is a potent STAT inhibitor with KD of 300 nM and 464 nM for STAT3 and STAT5 respectively
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Aobchem AOBCHEM
5000924269 3-BROMO-2- METHYLTHIO QUINOLIN
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Aobchem AOBCHEM
5000924302 2-METHYLQUINOLINE-6-BORONIC AC
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Selleck Chemical LLC Mefloquine HCl S4420-100mg
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Mefloquine HCl(Mefloquin hydrochloride) is a blood schizonticide by inhibiting hemozoin formation used as an antimalarial drug
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Selleck Chemical LLC Quinidine hydrochloride monohydrate S4681-1g
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Quinidine hydrochloride monohydrate is an anti-arrythmic agent and a potent potassium channel inhibitor with IC50 of 19 9 M
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