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Filtered Search Results
Medchemexpress LLC Urea, N-(2-((4-(diethylamino)butyl)amino)-6-(3,5-dimethoxyphenyl)pyrido(2,3-d)pyrimidin-7-yl)-N'-(1 | 219580-11-7 | MFCD08705327 | 99.9% | 523.7 g/mol | C28H41N7O3 | 200 MG
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PD173074 is a small-molecule research compound that potently inhibits fibroblast growth factor receptor 1 (FGFR1). It shows an FGFR1 IC50 of ~25 nM, inhibits VEGFR2 with an IC50 of 100-200 nM, and demonstrates approximately 1,000-fold selectivity over PDGFR and c-Src. It is supplied for laboratory research use as an analytical/research standard.
- Potent FGFR1 inhibitor (IC50 ≈ 25 nM).
- Also inhibits VEGFR2 (IC50 100-200 nM).
- Approximately 1,000-fold selectivity for FGFR1 over PDGFR and c-Src.
- High purity (≈99.9%).
- Molecular weight 523.7 g/mol.
- CAS number 219580-11-7.
- For research use only.
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Medchemexpress LLC 50-C2-C9-4TAIL 5 mg
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50-C2-C9-4TAIL 5MG
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Medchemexpress LLC DISODIUM 3 3 -SULFON 5G
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DISODIUM 3 3 -SULFON 5G
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Ambeed AMBEED
5000867179 3-HYDROXYISOXAZOLE-5-CARBO 1GR
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Ambeed AMBEED
5000869031 2-O4-C-METHYLENEADENOSIN 100MG
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Ambeed AMBEED
5000869182 4-METHOXYTHIOPHENE-3-CARBO 1GR
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Medchemexpress LLC LY2874455 200 mg
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LY2874455 200MG
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Medchemexpress LLC GALUNISERTIB 200 mg
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GALUNISERTIB 200MG
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Medchemexpress LLC SRS16-86 1 mg
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SRS16-86 1MG
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Medchemexpress LLC CEFSULODIN SODIUM 200 mg
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CEFSULODIN SODIUM 200MG
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MEDCHEMEXPRESS LLC RESIQUIMOD 10MG
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501872943 RESIQUIMOD 10MG
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eMolecules 24730-10-7 | Medchem Express | Dihydroergocristine (mesylate) | 5mg | 489863296 | HY-N2319 | MFCD00153792 | 707.84 | C36H45N5O8S
Pharmablock | 26-dichloro-4-methyl-3-nitro-pyridine | 500mg | 551319498 | PB03300 | 60010-03-9 | MFCD11110694 | 207.010 | C6H4Cl2N2O2
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Medchemexpress LLC Dosimertinib-d5 mesylate | 2403760-72-3 | 99.4% | C29H32D5N7O5S | 10MG
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Dosimertinib-d5 mesylate is the deuterated mesylate salt of dosimertinib, a third-generation epidermal growth factor receptor (EGFR) inhibitor. Provided as a research-grade reference standard for preclinical and analytical applications; not for human or veterinary use.
- Deuterated internal standard for analytical assays and mass spectrometry.
- High purity: 99.4%.
- Molecular formula: C29H32D5N7O5S.
- Available in small pack sizes (1-100 mg) suitable for method development.
- Mesylate salt form for improved handling and stability.
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Medchemexpress LLC Almonertinib mesylate | 2134096-06-1 | 99.7% | 621.75 | 25 MG
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Almonertinib mesylate (HS-10296 mesylate) is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR-sensitizing and T790M resistance mutations. It shows great inhibitory activity against T790M, T790M/L858R, and T790M/Del19 (IC50: 0.37, 0.29, and 0.21 nM, respectively), and is less effective against wild type (3.39 nM). It is used for the research of non-small cell lung cancer, and can also inhibit other EGFR sensitive mutations, including G719X, del19, L858R, and L861Q.
- Orally available
- Irreversible
- Third-generation EGFR tyrosine kinase inhibitor
- High selectivity for EGFR-sensitizing and T790M resistance mutations
- Great inhibitory activity against T790M, T790M/L858R and T790M/Del19
- Used for research of non-small cell lung cancer
- Inhibits EGFR sensitive mutations (G719X, del19, L858R, L861Q)
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Medchemexpress LLC Trovafloxacin mesylate | 147059-75-4 | MFCD00913361 | 99.8% | 512.46 g/mol | C21H19F3N4O6S | 1 ML
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Trovafloxacin mesylate is the mesylate salt of trovafloxacin, a broad-spectrum fluoroquinolone antibiotic that inhibits DNA gyrase and topoisomerase IV. It is used in research to study antibacterial activity and pannexin 1 (PANX1) channel function and inhibition.
- Broad-spectrum fluoroquinolone antibiotic that inhibits DNA gyrase and topoisomerase IV.
- Also reported as a pannexin 1 (PANX1) inhibitor with an IC50 around 4 μM.
- Available as a 10 mM solution in DMSO (1 mL) and as solid quantities for experimental flexibility.
- High purity: 99.8% (HPLC) as reported by supplier.
- CAS number 147059-75-4; molecular weight 512.46 g/mol.
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