Quinolines and derivatives
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000431998 MHI-148 25MG
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5000453136 L-CYSTATHIONINE DIH 5MG
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eMolecules 8-CHLORONAPHTHALEN-1-AMINE 10G
5000224120 8-CHLORONAPHTHALEN-1-AMINE 10G
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Medchemexpress LLC Panobinostat | 404950-80-7 | MFCD09833242 | 99.4% | 349.43 | C21H23N3O2 | 200 MG
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Panobinostat is a potent, orally active, non-selective histone deacetylase (HDAC) inhibitor supplied as a research-grade powder for laboratory use. It exhibits antineoplastic activity and is commonly used in epigenetic and cancer research, and in studies of apoptosis and autophagy. Not for human or veterinary use.
- Potent non-selective HDAC inhibitor with antineoplastic activity.
- High purity (99.4% by LCMS).
- Powder form, soluble in DMSO ≥ 100 mg/mL.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (1 year).
- Used in studies of apoptosis, autophagy, and cancer cell proliferation.
- Intended for research use only; not for human or veterinary use.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000391146 RALINEPAG 200MG
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5000435085 7-DEAZAXANTHINE 10G
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Apexbio Technology LLC TG101209 936091-14-4 200mg
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TG101209 (CAS 936091-14-4) is a structurally designed small molecule that functions as a selective inhibitor of Janus kinase 2 (JAK2) It inhibits the JAK/STAT signaling pathway particularly in cell lines harboring JAK2V617F or MPLW515L/K mutations commonly associated with polycythemia vera and primary myelofibrosis respectively In studies using multiple myeloma cell models TG101209 reduces the expression of phosphorylated JAK2 STAT3 and Bcl-xL while inducing overexpression of phosphorylated Erk and Akt This modulation of signaling pathways results in dose- and time-dependent cytotoxicity linked to cell cycle arrest and apoptosis supporting its utility in research on hematological malignancies driven by JAK2 dysregulation
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5000449022 5-AMINO-8-HYDROXYQUI 100MG
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eMolecules 2-FLUORO-5-4 4 5 5-TETRAME 1G
5000211082 2-FLUORO-5-4 4 5 5-TETRAME 1G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000378567 AP-III-A4 200MG
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Apexbio Technology LLC Clinofibrate 30299-08-2 200mg
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Clinofibrate (CAS 30299-08-2) is a small-molecule lipid-regulating agent that modulates cholesterol and triglyceride metabolism It acts by inhibiting hydroxymethylglutaryl coenzyme A reductase (HMGCR) a key enzyme in the biosynthetic pathway of cholesterol Clinofibrate demonstrates an inhibitory concentration (IC50) of 0 47 mM against HMGCR indicating its potential to suppress cholesterol synthesis It is primarily utilized in biomedical research focused on the regulation of plasma lipid levels and the investigation of therapeutic strategies for hypercholesterolemia and hypertriglyceridemia
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![Medchemexpress LLC N-(1-benzyl-2,3-dihydro-1H-pyrrolo[2,3-b]quinolin-4-yl)-2-phenylacetamide | 365565-02-2 | 99.3% | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000234673.png-250.jpg)
Medchemexpress LLC N-(1-benzyl-2,3-dihydro-1H-pyrrolo[2,3-b]quinolin-4-yl)-2-phenylacetamide | 365565-02-2 | 99.3% | 25 MG
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PGP-4008 is a selective P-glycoprotein (Pgp) inhibitor used in research to study multidrug resistance and Pgp-mediated drug transport in cellular and animal models.
- Selective Pgp inhibitor for multidrug resistance research.
- Reported purity approximately 99.3% by primary supplier.
- CAS number 365565-02-2; molecular formula C26H23N3O; molecular weight 393.5 g/mol.
- Typically supplied as a 25 MG solid; soluble in DMSO.
- For research use only; follow appropriate handling and storage.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000378251 ADIPORON 200MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000450913 DEFEROXAMINE MESYLA 25MG
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eMolecules 7-BROMOQUINOLINE 25G
5000226018 7-BROMOQUINOLINE 25G
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