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Filtered Search Results
Medchemexpress LLC Mefloquine | 53230-10-7 | 99.96% | 378.31 | 50 MG
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Mefloquine (Standard) is the analytical standard of Mefloquine, intended for research and analytical applications. It is an orally active and potent quinoline antimalarial agent and an anti-SARS-CoV-2 entry inhibitor. Mefloquine also acts as a K+ channel (KvQT1/minK) antagonist with an IC50 of approximately 1 μM. It can be utilized for malaria, systemic lupus erythematosus, and cancer research.
- Analytical standard of Mefloquine.
- Intended for research and analytical applications.
- Orally active and potent quinoline antimalarial agent.
- Anti-SARS-CoV-2 entry inhibitor.
- K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM.
- Applicable for malaria, systemic lupus erythematosus, and cancer research.
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
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Medchemexpress LLC Mefloquine (Standard) | 53230-10-7 | MFCD00869324 | 378.31 | 100 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Mefloquine (Standard) is the analytical standard of Mefloquine, intended for research and analytical applications. It is an orally active and potent quinoline antimalarial agent and an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. This analytical standard grade compound is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Orally active and potent quinoline antimalarial agent.
- Anti-SARS-CoV-2 entry inhibitor.
- K+ channel (KvQT1/minK) antagonist.
- Used for malaria, systemic lupus erythematosus, and cancer research.
- Analytical standard grade for qualitative, quantitative, and methodological research experiments.
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Medchemexpress LLC Cinchonine | 118-10-5 | MFCD00064372 | 99.7% | 294.39 g/mol | C19H22N2O | 50g
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Cinchonine is a natural compound present in Cinchona bark with antimalarial antitumor anti-inflammatory anti platelet-aggregation and anti-obesity properties Cinchonine inhibits cells proliferation and autophagy and induces apoptosis through activation of Caspase-3 Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells[1]
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Medchemexpress LLC Mefloquine (hydrochloride) | 51773-92-3 | 99.98% | 414.77 | 500 MG
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Mefloquine hydrochloride is a quinoline antimalarial agent and an anti-SARS-CoV-2 entry inhibitor. It acts as a K+ channel antagonist and is suitable for research in malaria, systemic lupus erythematosus, and cancer. It selectively inhibits prostate cancer cell growth and shows higher anti-SARS-CoV-2 activity than Hydroxychloroquine. Animal studies indicate it can reverse lower vertebral cancellous bone volume.
- Quinoline antimalarial agent
- Anti-SARS-CoV-2 entry inhibitor
- K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM
- Selectively inhibits prostate cancer cell growth with an IC50 of ~10 μM
- Induces hyperpolarization of mitochondrial membrane potential (MMP) and ROS generation
- Shows higher anti-SARS-CoV-2 activity than Hydroxychloroquine
- Can be used for malaria, systemic lupus erythematosus and cancer research
- Reverses lower vertebral cancellous bone volume and bone formation in old mice
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Apexbio Technology LLC Mefloquine hydrochloride 51773-92-3 10mM (in 1mL DMSO)
Mefloquine hydrochloride is a quinoline-based antimalarial compound structurally related to quinidine with demonstrated inhibitory effects on Plasmodium falciparum It functions primarily through modulation of potassium ion channels displaying an IC50 around 1 M against KvLQT1/minK channel currents and approximately 5 6 M against HERG channel currents Research indicates that mefloquine induces cellular oxidative stress modulating intracellular signaling pathways including Akt phosphorylation ERK JNK and AMPK in vitro Current studies also explore its potential cytotoxic activity toward cancer cell lines and evaluate effectiveness against urinary schistosomiasis in phase 2 clinical trials
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Medchemexpress LLC Quinine | 130-95-0 | 25 G
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Quinine is an alkaloid derived from the bark of the cinchona tree, acting as an anti-malaria agent and a potassium channel inhibitor. It inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV with an IC50 of 169 μM.
- Derived from cinchona tree bark
- Acts as an anti-malaria agent
- Functions as a potassium channel inhibitor
- Inhibits WT mouse Slo3 (KCa5.1) channel currents
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Apexbio Technology LLC HYDROQUININE-100MG
Hydroquinine (CAS No 522-66-7) is a chemical compound primarily used in biomedical research originating as a derivative of quinine Its mechanism of action involves modulation of certain pharmacological receptors and pathways though its precise molecular targets may vary across studies In vitro hydroquinine exhibits a range of activities generally falling within the nanomolar to low micromolar concentrations suggesting significant potency This compound is often employed in cell model studies and animal research contributing to drug screening and pharmacological investigations The experimental concentrations of hydroquinine typically depend on the specific research design allowing researchers to tailor dosages to their study objectives and model systems
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Apexbio Technology LLC HYDROQUINIDINE-200MG
Hydroquinidine (CAS No 1435-55-8) is utilized in biomedical research primarily for its role as a cardioactive compound originating from the bark of the Cinchona tree It operates by modulating cardiac ion channels particularly targeting sodium and potassium channels to stabilize myocardial electrical activity In vitro its effective concentrations are typically observed in the nanomolar to low micromolar range This compound is frequently utilized in studies involving cardiac cell models and has applications in animal studies for examining cardiac arrhythmias It is also employed in drug screening processes aimed at discovering and evaluating new antiarrhythmic agents Experimental concentrations typically depend on the specific research design ensuring adaptability across varied experimental setups
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Selleck Chemical LLC Hydroquinine S5114-25mg
Hydroquinine (Dihydroquinine) also known as dihydroquinine is an organic compound and as a cinchona alkaloid closely related to quinine
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Selleck Chemical LLC Hydroquinidine S4658-100mg
Hydroquinidine (Dihydroquinidine Hydroconchinine Hydroconquinine Dihydroquinine) is an antiarrhythmic agent
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Medchemexpress LLC Hydroquinine | 1 G
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Hydroquinine | 1 G
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Selleck Chemical LLC Mefloquine HCl S4420-100mg
Mefloquine HCl(Mefloquin hydrochloride) is a blood schizonticide by inhibiting hemozoin formation used as an antimalarial drug
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Medchemexpress LLC Resiquimod | 144875-48-9 | 99.9% | 314.39 | 500 MG
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Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6, and IFN-α. It is intended for research use only.
- TLR7/TLR8 agonist
- Induces upregulation of cytokines like TNF-α, IL-6, and IFN-α
- Available in solid and solution forms
- Used in various research areas including anti-infection, immunology/inflammation
- Can be used to induce systemic lupus erythematosus models
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TARGETMOL CHEMICALS INC PRADEFOVIR MESYLATE 5MG
502694095 PRADEFOVIR MESYLATE 5MG
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TARGETMOL CHEMICALS INC VIGABATRIN 25MG
502693609 VIGABATRIN 25MG
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