Quinolines and derivatives
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Filtered Search Results
TARGETMOL CHEMICALS INC Pneumocandin B0 200MG
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Also available in 1 mL, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes.Pneumocandin B0 (L-688786) is a natural product and a key intermediate in the synthesis of the antifungal agent. Purity 99.23%
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Apexbio Technology LLC Clinofibrate 30299-08-2 200mg
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Clinofibrate (CAS 30299-08-2) is a small-molecule lipid-regulating agent that modulates cholesterol and triglyceride metabolism It acts by inhibiting hydroxymethylglutaryl coenzyme A reductase (HMGCR) a key enzyme in the biosynthetic pathway of cholesterol Clinofibrate demonstrates an inhibitory concentration (IC50) of 0 47 mM against HMGCR indicating its potential to suppress cholesterol synthesis It is primarily utilized in biomedical research focused on the regulation of plasma lipid levels and the investigation of therapeutic strategies for hypercholesterolemia and hypertriglyceridemia
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Medchemexpress LLC Pyrroloquinoline quinone disodium salt | 122628-50-6 | 98.0% | 374.17 g/mol | C14H4N2Na2O8 | 50 MG
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Pyrroloquinoline quinone disodium salt is the disodium salt form of the redox cofactor PQQ supplied for research and analytical applications. The material is a pink to red solid used in studies of metabolism, oxidative stress, and cellular signaling. It is provided as a small powdered reagent with recommended sealed storage to preserve stability.
- Redox co-factor used in metabolic and oxidative stress research.
- High purity suitable for analytical and biological applications.
- Pink to red solid that is easy to weigh and handle.
- Stable when stored sealed and protected from moisture.
- Available in small powder pack sizes for laboratory use.
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Apexbio Technology LLC Vinpocetine 42971-09-5 200mg
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Vinpocetine (CAS 42971-09-5) is a selective inhibitor of cyclic GMP phosphodiesterase (PDE) exhibiting a Ki of 14 2 M for Ca2 -dependent PDE in vitro It acts as a non-competitive inhibitor effectively modulating intracellular cGMP levels in smooth muscle In rat aortic cytosolic preparations vinpocetine inhibits Ca2 -PDE activity significantly while demonstrating minimal inhibition of Ca2 -independent cGMP PDE and cAMP PDE (Ki values 1000 M) Additionally vinpocetine attenuates 5-HT-induced contractions in intact rat aorta with an EC50 of 1 M This compound is used in research to explore mechanisms of smooth muscle relaxation and PDE regulation
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000379723 LY2874455 200MG
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Aobchem AOBCHEM
5000864463 1-BROMO-2 4-DIMETHOXY-5-METHYL
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000379128 PRACINOSTAT 200MG
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![Apexbio Technology LLC prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens] 1mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000096894.png-250.jpg)
Apexbio Technology LLC prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens] 1mg
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Prostate apoptosis response protein PAR-4 2-7 is a short peptide targeting transcriptional regulation pathways It is designed to modulate transcription factor activity thereby influencing apoptosis mechanisms particularly in prostate cells PAR-4 2-7 exerts its biological activity primarily through interaction with transcription factors via a leucine zipper zinc finger domain facilitating apoptosis in transformed or malignant cells while sparing normal cells Based on these properties PAR-4 2-7 holds research potential in studies investigating tumor suppression mechanisms and transcription-mediated apoptosis regulation in oncology and therapeutic research
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Selleck Chemical LLC FLI-06
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FLI-06 is a novel inhibitor of Notch signaling with EC50 of 2 3 M
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Aobchem AOBCHEM
5000866205 8-BROMO-5-METHYLQUINOLINE 500M
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000431224 SULFO-CY7.5 MALEIMID 5MG
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Medchemexpress LLC Cyanine5.5 amine | 2097714-45-7 | 99.3% | 753.88 | 100 MG
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Cyanine5.5 amine is a Cy5.5 analogue and a near-infrared (NIR) fluorescent dye (Ex=648 nm, Em=710 nm). It can be used in the preparation of Cy5.5-labeled nanoparticles for tracking and imaging with low fluorescence background using confocal microscopy.
- Solid appearance
- Purple to purplish red color
- Excitation wavelength: 648 nm
- Emission wavelength: 710 nm
- Soluble in DMSO at 100 mg/mL
- Store at -20°C, sealed, away from moisture and light
- Suitable for research use only
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Medchemexpress LLC Capivasertib | 1143532-39-1 | C21H25ClN6O2 | 200 MG
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Capivasertib (AZD5363) is an orally active and potent pan-AKT kinase inhibitor, effectively inhibiting Akt1, Akt2, and Akt3 with high selectivity. This compound demonstrates in vitro inhibition of cancer cell proliferation, leading to apoptosis and G1 cell cycle arrest. In vivo studies confirm its good oral bioavailability, favorable pharmacokinetic properties, and significant ability to inhibit tumor growth in various human xenograft models. It is currently undergoing clinical evaluation.
- Potent pan-AKT kinase inhibitor
- Highly selective for Akt over other kinases
- Inhibits proliferation in diverse cancer cell lines
- Induces apoptosis and G1 cell cycle arrest
- Exhibits good oral bioavailability
- Effectively inhibits tumor growth in xenograft models
- Inhibits P70S6K, PKA, and ROCK2 activity
- Suppresses phosphorylation of AKT substrates
- Induces FOXO3a nuclear translocation
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Medchemexpress LLC 5'-O-(4,4'-Dimethoxytrityl)-5-methoxyuridine | 2095417-73-3 | C31H32N2O9 | 50 MG
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5'-O-(4,4'-Dimethoxytrityl)-5-methoxyuridine is a purine nucleoside analog. This chemical compound is known for its broad antitumor activity, particularly targeting indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and induction of apoptosis, making it a subject of interest in cancer research.
- Purine nucleoside analog
- Exhibits broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000369114 BREXPIPRAZOLE 200MG
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