Quinolines and derivatives
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Filtered Search Results
Ambeed AMBEED
5000884217 METHYL QUINOLINE-2-CARBO 5G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Ambeed AMBEED
5000884891 8-QUINOLINECARBOXYLIC AC 10G
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Chem-Impex International, Inc. Quinoline-6-carboxylic acid | MFCD00047613 | 1G
Quinoline-6-carboxylic acid, MFCD00047613, 1G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Ambeed 1 2 3 4Tetrahydroquinoline
1,2,3,4-Tetrahydroquinoline, 635-46-1, 98%
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Chem-Impex International, Inc. 4-Quinolinecarboxylic acid | MFCD00006782 | 1G
4-Quinolinecarboxylic acid, MFCD00006782, 1G
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Chemscene ChemScene | 2-Oxo-1,2-dihydroquinoline-6-carboxylic acid | 250MG | CS-0135806 | 0.95 | 70639-78-0| MFCD03840853 | 189.17
ChemScene | 2-Oxo-1,2-dihydroquinoline-6-carboxylic acid | 250MG | CS-0135806 | 0.95 | 70639-78-0| MFCD03840853 | 189.17
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Sigma Aldrich Fine Chemicals Biosciences Bicinchoninic acid disodium salt hydrate >=98% (HPLC) | 979-88-4 (anhydrous) | MFCD10567219 | 1G
Bicinchoninic acid disodium salt hydrate >=98% (HPLC) | Purity: >=98% (HPLC) | 979-88-4 (anhydrous) | MFCD10567219 | 1G
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Selleck Chemical LLC Kynurenic acid-100mg
Kynurenic acid (Quinurenic acid, Kynurenate), a natural metabolite of tryptophan via the kynurenine pathway, is a broad-spectrum excitatory amino acid antagonist; It proved to be an antagonist at NMDA, kainate and AMPAreceptors.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC TLR7/8 agonist 1 dihydrochloride | 1620278-72-9 | MFCD31657341 | 99.7% | 432.39 | C22H27Cl2N5 | 10 MG
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TLR7/8 agonist 1 dihydrochloride is a small-molecule imidazoquinoline research compound that acts as a dual agonist of Toll-like receptors 7 and 8. It is intended for use in immunology and inflammation studies and demonstrates low-nanomolar activity in receptor assays, suitable for both in vitro and in vivo experimental applications.
- Dual agonist of TLR7 and TLR8 with low-nanomolar potency.
- High reported purity (99.7%).
- Molecular weight 432.39 and formula C22H27Cl2N5.
- High solubility in DMSO (83.33 mg/mL) and compatible with common in vivo vehicles.
- Supplied as an off-white to light yellow solid and available as a DMSO solution.
- Storage: 4°C sealed; in solvent store at -80°C for long term.
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Medchemexpress LLC Benzyl-PEG5-amine | 86770-77-6 | 98.0% | C17H29NO5 | 1 G
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Benzyl-PEG5-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. It has a molecular weight of 327.42, appears as a liquid, and is colorless to light yellow.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Molecular weight of 327.42
- Liquid appearance
- Colorless to light yellow
- Purity of 98.0%
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Medchemexpress LLC Benzyl-PEG5-amine | 86770-77-6 | 98.0% | C17H29NO5 | 25 MG
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Benzyl-PEG5-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are molecules with two ligands connected by a linker, one binding to an E3 ubiquitin ligase and the other to a target protein. This mechanism exploits the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Azido-PEG10-amine | 912849-73-1 | 97.0% | C22H46N4O10 | 50 MG
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Azido-PEG10-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a click chemistry reagent containing an Azide group, which can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an Azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Urea, N-(2-((4-(diethylamino)butyl)amino)-6-(3,5-dimethoxyphenyl)pyrido(2,3-d)pyrimidin-7-yl)-N'-(1 | 219580-11-7 | MFCD08705327 | 99.9% | 523.7 g/mol | C28H41N7O3 | 200 MG
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PD173074 is a small-molecule research compound that potently inhibits fibroblast growth factor receptor 1 (FGFR1). It shows an FGFR1 IC50 of ~25 nM, inhibits VEGFR2 with an IC50 of 100-200 nM, and demonstrates approximately 1,000-fold selectivity over PDGFR and c-Src. It is supplied for laboratory research use as an analytical/research standard.
- Potent FGFR1 inhibitor (IC50 ≈ 25 nM).
- Also inhibits VEGFR2 (IC50 100-200 nM).
- Approximately 1,000-fold selectivity for FGFR1 over PDGFR and c-Src.
- High purity (≈99.9%).
- Molecular weight 523.7 g/mol.
- CAS number 219580-11-7.
- For research use only.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Foliglurax monohydrochloride | 2133294-96-7 | 98.57% | 457.97 | 10 MG
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Foliglurax monohydrochloride is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM), with an EC50 of 79 nM. It exhibits an antiparkinsonian effect.
- Highly selective and potent.
- Brain-penetrant mGluR4 PAM.
- EC50 of 79 nM for mGlu4.
- Exhibits antiparkinsonian effect.
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Apexbio Technology LLC MK-8245 1030612-90-8 200mg
MK-8245 (CAS 1030612-90-8) is a potent liver-selective small molecule inhibitor of stearoyl-CoA desaturase (SCD) SCD1 catalyzes fatty acid desaturation and represents a target for treating type II diabetes obesity dyslipidemia and other metabolic disorders MK-8245 demonstrates strong inhibitory activity against rat mouse and human SCD1 with an IC50 of approximately 1 nM and displays liver-specific tissue distribution mediated by organic anion transporting polypeptides (OATPs) Animal studies revealed MK-8245 reduces blood glucose levels and hepatic triglycerides dose-dependently supporting its application in metabolic disease research
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