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Filtered Search Results
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000597122 GUANIDINOETHYL SULFO 1G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000597130 GUANIDINOETHYL SULFO 500MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000597133 GUANIDINOETHYL SULFO 5G
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eMolecules EMOLECULES INC
501713338 N N-DISUCCINIMIDYL CARBON 25G
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Environmental Sampling Supply Inc ENVIRONMENTAL SAMPLING SUPPLY INC
NC3897147 40ML AOT/25MG ASCB/200MG MALC
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TARGETMOL CHEMICALS INC SB 202190 200MG
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Also available in 1 mL, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38alpha and p38beta2 (IC50=50/100 nM) selectively and cell-permeably. SB 202190 has antitumor activity and also induces the differentiation of human embryonic stem cells into cardiomyocytes. Purity 99.67%
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TARGETMOL CHEMICALS INC Bosutinib 200MG
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Also available in 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50 1 nM) and Src (IC50 1.2 nM) kinases. Purity 99.84%
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Apexbio Technology LLC Isocytosine 108-53-2 200mg
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Isocytosine (CAS 108-53-2) is a non-canonical nucleobase and a structural isomer of cytosine It serves as an analog in nucleic acid research notably as a component of expanded genetic systems such as hachimoji RNA and can pair with isoguanine to model non-standard base pairing Mechanistically isocytosine has been shown to modulate specific signaling pathways and enzyme activities in experimental systems It is widely utilized in molecular biology and genetics to investigate alternative base-pairing nucleic acid stability and the physicochemical properties of synthetic genetic polymers
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Medchemexpress LLC Eltrombopag | 496775-61-2 | MFCD20926253 | C25H22N4O4 | 200 MG
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Eltrombopag is an orally active thrombopoietin receptor nonpeptide agonist. It exhibits thrombopoietic activity and has been studied for low blood platelet counts in chronic immune thrombocytopenia. It is also used in cardiovascular research, shows strong inhibitory effects against multidrug-resistant Staphylococcus aureus, and can induce apoptosis in hepatocellular carcinoma (HCC).
- Exhibits thrombopoietic activity
- Used in research for low blood platelet counts in chronic immune thrombocytopenia
- Utilized in cardiovascular research
- Shows strong inhibitory effects against multidrug-resistant Staphylococcus aureus
- Can induce apoptosis in hepatocellular carcinoma (HCC)
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Medchemexpress LLC Benzamide, 5-(3-azetidinylamino)-N-[(1R)-1-[3-[5-[[[(1S,3R)-3-hydroxycyclopentyl)amino]methyl]-2- | 2817811-16-6 | C29H36N4O2S | 200 MG
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XR8-89 is a potent papain-like protease (PLpro) inhibitor with an IC50 value of 0.1 μM. This compound induces conformational changes in SARS-CoV-2 papain-like protease, effectively inhibiting SARS-CoV-2 replication, making it suitable for research applications.
- Potent papain-like protease (PLpro) inhibitor
- IC50 value of 0.1 μM against papain-like protease
- Induces conformational changes in SARS-CoV-2 papain-like protease
- Inhibits SARS-CoV-2 replication
- For SARS-CoV-2 research use
- Purity of 97.13%
- Appears as a light yellow to yellow solid
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Medchemexpress LLC Paliperidone (9-Hydroxyrisperidone) | 144598-75-4 | 99.4% | C23H27FN4O3 | 200 MG
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Paliperidone (9-Hydroxyrisperidone) is the major active metabolite of Risperidone, functioning as a dopamine D2 and 5-HT2A antagonist. It also exhibits antagonist activity at α1 and α2 adrenergic receptors and H1-histaminergic receptors, demonstrating efficacy as an antipsychotic agent against schizophrenia.
- Major active metabolite of risperidone
- Dopamine D2 antagonist
- 5-HT2A antagonist
- Antagonist at α1 and α2 adrenergic receptors
- Antagonist at H1-histaminergic receptors
- Effective antipsychotic agent against schizophrenia
- For research use only
- Increases caspase-3 activity in neuroblastoma cells
- May modulate Akt1/GSK3β pathway to protect SK-N-SH cells from glutamate damage
- Can protect SK-N-SH cells from apoptosis induced by glutamate
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Medchemexpress LLC 1H-Imidazole-2-carbaldehyde | 10111-08-7 | 96.09 | 25 G
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1H-Imidazole-2-carbaldehyde is a biochemical reagent used in life science research. It functions as a novel protein tyrosine phosphatase 1B (PTP1B) inhibitor, with applications in suppressing type-2 diabetes. Additionally, it is utilized in the preparation of tridentate Schiff-base carboxylate-containing ligands and studies involving imidazole-directed allylation of aldimines.
- Biochemical reagent for life science research.
- Functions as a novel protein tyrosine phosphatase 1B (PTP1B) inhibitor.
- Applied to suppress type-2 diabetes.
- Used in the preparation of tridentate Schiff-base carboxylate-containing ligands.
- Involved in the study of imidazole-directed allylation of aldimines.
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Medchemexpress LLC Selonsertib | 1448428-04-3 | 99.1% | 445.49 | 200 MG
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Selonsertib (GS-4997) is an orally bioavailable, selective apoptosis signal-regulating kinase 1 (ASK1) inhibitor with a pIC50 of 8.3. It has been evaluated as an experimental treatment for diabetic nephropathy and kidney fibrosis. It is a highly selective and potent once-daily oral ASK1 inhibitor that competes with ATP in the ASK1 catalytic kinase domain.
- Orally bioavailable.
- Selective apoptosis signal-regulating kinase 1 (ASK1) inhibitor.
- pIC50 of 8.3 for ASK1.
- Competes with ATP in the ASK1 catalytic kinase domain.
- Highly selective and potent once-daily oral ASK1 inhibitor.
- Evaluated as an experimental treatment for diabetic nephropathy and kidney fibrosis.
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Medchemexpress LLC (R)-Baclofen (Arbaclofen) | 69308-37-8 | 99.50% | 213.66 | 200 MG
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R-Baclofen (Arbaclofen) is a selective GABAB receptor agonist commonly used in research. It exhibits agonist activity at human GABA-B B1/B2 receptors expressed in HEK293 cells, as assessed by the inhibition of forskolin-stimulated cAMP accumulation. In vivo studies demonstrate its ability to suppress audiogenic seizures in Fmr1-knockout mice and significantly reduce seizure incidence with acute administration.
- Selective GABAB receptor agonist.
- Exhibits agonist activity at human GABA-B B1/B2 receptors.
- Suppresses audiogenic seizures in Fmr1-knockout mice.
- Reduces seizure incidence in mice.
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Medchemexpress LLC Oxyclozanide | 2277-92-1 | 98.7% | 401.46 | 200 MG
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Oxyclozanide is an orally active salicylanilide anthelmintic agent that primarily functions by uncoupling oxidative phosphorylation in flukes. It also exhibits good anti-adenovirus, anti-biofilm, antifungal, and antibacterial activities.
- Orally active salicylanilide anthelmintic agent.
- Mainly acts by uncoupling oxidative phosphorylation in flukes.
- Shows good anti-adenovirus, anti-biofilm, antifungal, and antibacterial activity.
- Effective against meticillin-sensitive and meticillin-resistant S. pseudintermedius isolates.
- Inhibits methicillin-resistant S. aureus (MRSA).
- Demonstrates antiparasitic effectiveness in sheep and cattle.
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