Quinolines and derivatives
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Filtered Search Results
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5000369984 PRMT5-IN-31 100MG
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Medchemexpress LLC Sulfo-Cy3 amine | 2183440-43-7 | 99.66% | 714.93 | 100 MG
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Sulfo-Cy3 amine is a dye derivative of Cyanine 3 (Cy3) that bears an amine group. The sulfonate ion enhances the compound's water solubility, making it suitable for aqueous solutions. Cy3 is a fluorescent dye that typically exhibits a fluorescence spectrum in the green to orange wavelength range. The amine functionality allows Sulfo-Cy3 amine to react with carboxyl groups to form covalent bonds.
- Binds to biological molecules such as proteins and antibodies.
- Enables tracking of location and dynamic changes within biological samples.
- Enhanced water solubility.
- Suitable for aqueous solutions.
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eMolecules ChemScene / Ethyl 2-hydroxyquinoline-4-carboxylate / 250mg / 654744479 / CS-0208320 / 0.000 / 5466-27-3 / MFCD02041443 / 217.224 / C12H11NO3
ChemScene / Ethyl 2-hydroxyquinoline-4-carboxylate / 250mg / 654744479 / CS-0208320 / 0.000 / 5466-27-3 / MFCD02041443 / 217.224 / C12H11NO3
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Medchemexpress LLC 2-Aminoquinoline | 580-22-3 | 144.18 | 5 G
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2-Aminoquinoline (2-Quinolinamine) is a promising compound identified as a bioavailable nNOS inhibitor. While it exhibits low human nNOS inhibition and limited selectivity against human eNOS, it demonstrates antiviral activity against the vaccinia virus and shows potential for research in antineurodegenerative agents.
- Acts as a nNOS inhibitor
- Exhibits antiviral activity against vaccinia virus
- Potential for antineurodegenerative agent research
- Solid appearance
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Medchemexpress LLC Rivastigmine (ENA 713 free base) | 123441-03-2 | 99.9% | 250.34 | 200 MG
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Rivastigmine (ENA 713 free base) | 123441-03-2 | 99.9% | 250.34 | 200 MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000369099 KRAS INHIBITOR-31 100MG
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![Medchemexpress LLC Acetamide, N-[4-(aminosulfonyl)phenyl]- | 121-61-9 | MFCD00035784 | 100.0% | 214.24 | C8H10N2O3S | 200 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000210841.png-250.jpg)
Medchemexpress LLC Acetamide, N-[4-(aminosulfonyl)phenyl]- | 121-61-9 | MFCD00035784 | 100.0% | 214.24 | C8H10N2O3S | 200 MG
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N-Acetylsulfanilamide is a research-grade small molecule reported to have potential anti-infective activity. It is supplied as a white to off-white solid and is commonly used as a reference standard or for laboratory research.
- Cas number 121-61-9.
- Molecular weight 214.24.
- Purity 99.97% (manufacturer listed).
- Appearance white to off-white solid.
- Available pack sizes include 200 MG.
- Documentation available: datasheet, certificate of analysis, and safety data sheet.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000383506 SRS16-86 25MG
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eMolecules ChemScene / 4-Bromo-6-nitroquinoline / 100mg / 694122565 / CS-0041424 / 0.000 / 860195-53-5 / MFCD08688607 / 253.055 / C9H5BrN2O2
ChemScene / 4-Bromo-6-nitroquinoline / 100mg / 694122565 / CS-0041424 / 0.000 / 860195-53-5 / MFCD08688607 / 253.055 / C9H5BrN2O2
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eMolecules BISPERFLUOROPHENYL CARBO 10G
5000224245 BISPERFLUOROPHENYL CARBO 10G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000338417 IDELALISIB 200MG
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Apexbio Technology LLC MI-2(Synonyms: Menin-MLL Inhibitor MI-2, MI2, MI 2, Menin inhibitor MI-2), 200mg, CAS: 1271738-62-5.
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MI-2 (CAS 1271738-62-5) is a small molecule inhibitor targeting the menin-MLL protein-protein interaction with an IC50 of 0 45 M The formation of menin-MLL fusion protein complexes resulting from chromosomal rearrangements plays an essential role in the pathogenesis of acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) MI-2 selectively binds wild-type menin disrupting its interaction with MLL-fusion proteins such as MLL-AF9 thereby inhibiting cellular proliferation and colony formation in MLL-AF9-transduced mouse bone marrow cells MI-2 serves as a research tool in studies of leukemia biology and menin-associated oncogenesis
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Apexbio Technology LLC BGJ398(Synonyms: Infigratinib, NVP-BGJ398, BGJ-398, BGJ 398), 200mg, CAS: 872511-34-7.
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BGJ398 (CAS 872511-34-7) also known as NVP-BGJ398 is an orally bioavailable small-molecule inhibitor targeting fibroblast growth factor receptors (FGFRs) It selectively inhibits receptor tyrosine kinase activity of FGFR1 FGFR2 FGFR3 and FGFR4 which are critical mediators in signal transduction pathways involved in cell proliferation differentiation and survival In preclinical studies BGJ398 suppresses proliferation and induces apoptosis in FGFR-dependent cancer cells additionally it demonstrates antitumor activity in xenograft tumor models BGJ398 is utilized as a research tool in oncology studies investigating FGFR-driven malignancies
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eMolecules Pharmablock 7-bromoisoquinoline 100mg 551128246 PBN2011270 0 000 58794-09-5 MFCD07368661 208 058 C9H6BrN
Pharmablock 7-bromoisoquinoline 100mg 551128246 PBN2011270 0 000 58794-09-5 MFCD07368661 208 058 C9H6BrN
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Medchemexpress LLC CP 339818 (hydrochloride) | 478341-55-8 | 99.6% | 340.89 | 1 MG
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CP 339818 hydrochloride is a non-peptide blocker of Kv1.3 (IC50 = 200 nM) and Kv1.4 channels. It also inhibits HCN channels with IC50s of 18.9 μM and 43.4 μM against HCN1 and HCN4 (high Cl-), respectively. The compound exhibits significantly weaker blocking effects on Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2 channels. It can be utilized for studying the physiological functions of HCN and Kv channels.
- Non-peptide Kv1.3 and Kv1.4 channel blocker.
- Inhibits HCN channels (HCN1 and HCN4).
- Selectively blocks Kv1.3, inhibiting human T cell activation.
- Useful for studying physiological functions of HCN and Kv channels.
- Suppresses human T cell activation.
- Effectively blocks remaining outward potassium current in Kv2.1⁻/⁻ β cells.
- Inhibitory effect on HCN1 and HCN4 is weakened in low-concentration Cl- internal solution and is voltage-dependent.
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