Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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1,366 – 1,380 of 5,523 results

1,366

MEDCHEMEXPRESS LLC Bosutinib hydrate | 918639-08-4 | MFCD29920031 | 100.0% | 548.46 g/mol | C26H31Cl2N5O4 | 200 MG

Bosutinib hydrate is a small-molecule dual Src/Abl tyrosine kinase inhibitor supplied as a white to off-white solid for research use. It exhibits low-nanomolar potency against Src and Abl kinases and is intended for biochemical and cell-based studies; supporting documents such as SDS and COA are provided for analytical verification and safe handling.

Dual Src and Abl kinase inhibition at low-nanomolar concentrations.
High reported purity suitable for research applications.
Available in multiple packaging sizes, including 200 MG.
White to off-white solid appearance for easy handling.
Storage and stability guidance provided for solid and solution forms.
COA and SDS available to support quality and safety use.

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1,367

MEDCHEMEXPRESS LLC Luminespib | 747412-49-3 | MFCD14635361 | 99.8% | 465.54 | C26H31N3O5 | 200 MG

Luminespib (VER-52296) is a third-generation heat shock protein 90 (HSP90) inhibitor supplied as a 200 mg powder for research and analytical applications. It shows low-nanomolar potency against HSP90α and HSP90β and is provided as a high-purity analytical standard.

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1,368

MEDCHEMEXPRESS LLC Trovafloxacin mesylate | 147059-75-4 | MFCD00913361 | 99.8% | 512.46 g/mol | C21H19F3N4O6S | 1 ML

Trovafloxacin mesylate is the mesylate salt of trovafloxacin, a broad-spectrum fluoroquinolone antibiotic that inhibits DNA gyrase and topoisomerase IV. It is used in research to study antibacterial activity and pannexin 1 (PANX1) channel function and inhibition.

Broad-spectrum fluoroquinolone antibiotic that inhibits DNA gyrase and topoisomerase IV.
Also reported as a pannexin 1 (PANX1) inhibitor with an IC50 around 4 μM.
Available as a 10 mM solution in DMSO (1 mL) and as solid quantities for experimental flexibility.
High purity: 99.8% (HPLC) as reported by supplier.
CAS number 147059-75-4; molecular weight 512.46 g/mol.

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1,369

MEDCHEMEXPRESS LLC Trovafloxacin mesylate | 147059-75-4 | MFCD00913361 | 99.8% | 512.46 g/mol | C21H19F3N4O6S | 25 MG

Trovafloxacin mesylate is a broad-spectrum fluoroquinolone antibiotic and selective pannexin 1 (PANX1) inhibitor supplied as a high-purity solid for research use. It inhibits bacterial DNA gyrase and topoisomerase IV and blocks PANX1 inward currents (IC50 ≈ 4 μM), making it suitable for antibacterial mechanism and ion channel studies.

Broad-spectrum antibacterial activity against Gram-positive, Gram-negative, and anaerobic organisms.
Inhibits DNA gyrase and topoisomerase IV to block bacterial replication.
Selective PANX1 inhibition useful for ion channel and apoptotic fragmentation studies.
High stated purity for consistent experimental results.
Stable solid form with recommended storage under nitrogen at -20°C.

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1,370

MEDCHEMEXPRESS LLC Urea, N-(2-((4-(diethylamino)butyl)amino)-6-(3,5-dimethoxyphenyl)pyrido(2,3-d)pyrimidin-7-yl)-N'-(1 | 219580-11-7 | MFCD08705327 | 99.9% | 523.7 g/mol | C28H41N7O3 | 200 MG

PD173074 is a small-molecule research compound that potently inhibits fibroblast growth factor receptor 1 (FGFR1). It shows an FGFR1 IC50 of ~25 nM, inhibits VEGFR2 with an IC50 of 100-200 nM, and demonstrates approximately 1,000-fold selectivity over PDGFR and c-Src. It is supplied for laboratory research use as an analytical/research standard.

Potent FGFR1 inhibitor (IC50 ≈ 25 nM).
Also inhibits VEGFR2 (IC50 100-200 nM).
Approximately 1,000-fold selectivity for FGFR1 over PDGFR and c-Src.
High purity (≈99.9%).
Molecular weight 523.7 g/mol.
CAS number 219580-11-7.
For research use only.

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1,371

MEDCHEMEXPRESS LLC 3-Thiazolidinepropanoic acid, 5-(5-chloro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo- | 1426138-42-2 | 98.0% | 368.82 g/mol | C14H9ClN2O4S2 | 200 MG

FX1 is a small-molecule inhibitor of the transcriptional repressor BCL6, used as a research tool to probe BCL6-mediated transcriptional regulation and apoptosis. It is supplied as a solid and is suitable for biochemical and cellular studies.

Inhibits BCL6 with IC50 ≈ 35 μM
High purity (98.0%) suitable for research applications
Solid form, pink to red color
Molecular formula C14H9ClN2O4S2; molecular weight 368.82 g/mol
Available in multiple pack sizes including 200 MG
Powder storage: -20°C (3 years) or 4°C (2 years)
Intended for biochemical assays and cellular pathway studies

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1,372

MEDCHEMEXPRESS LLC Ruboxistaurin mesylate | 192050-59-2 | 99.9% | 564.65 g/mol | C29H32N4O6S | 50 MG

Ruboxistaurin mesylate is an orally active, selective, ATP-competitive protein kinase C beta (PKCβ) inhibitor used in preclinical research on diabetic complications, retinal disorders, and cardiovascular conditions. Supplied as the mesylate salt, it is an orange-to-red solid with molecular formula C29H32N4O6S and molecular weight 564.65 g/mol.

Selective PKCβ inhibition with low nanomolar potency (IC50 ~4.7-5.9 nM).
Mesylate salt form for improved stability and handling.
High purity (99.87%) suitable for research applications.
Orange-to-red solid, convenient for solid-state storage.
Molecular formula C29H32N4O6S and molecular weight 564.65 g/mol.

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1,373

MEDCHEMEXPRESS LLC Acridine orange (hydrochloride) | 65-61-2 | MFCD00150070 | 99.7% | 301.81 g/mol | C17H20ClN3 | 1 ML

Acridine Orange hydrochloride is a cell-permeable, nucleic acid-selective fluorescent dye used to differentially stain DNA and RNA. In solution it emits green fluorescence when bound to double-stranded DNA (~530 nm) and orange/red fluorescence when bound to single-stranded DNA or RNA (~640 nm). Commonly supplied as a 10 mM solution in DMSO for laboratory research use.

Cell-permeable nucleic acid-selective fluorescent dye.
Distinguishes double-stranded DNA (green) from single-stranded DNA/RNA (orange/red).
Available as a 10 mM solution in DMSO (1 mL) or as a solid form.
Suitable for fluorescence microscopy and flow cytometry applications.
Molecular formula C17H20ClN3; molecular weight 301.81 g/mol.
For research use only; not for human or clinical use.

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1,374

MEDCHEMEXPRESS LLC SLF-amido-C2-COOH 10mg | 1092369-24-8 | 10MG

SLF-amido-C2-COOH (PROTAC FKBP12-binding moiety 1) is a synthetic ligand for FKBP (SLF) SLF-amido-C2-COOH (PROTAC FKBP12-binding moiety 1) can be used in the synthesis of PROTACs[1

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1,375

MEDCHEMEXPRESS LLC 6-[2-[4-[(4-fluorophenyl)phenylmethylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one | 93076-89-2 | MFCD00055114 | 99.8% | 459.58 g·mol⁻¹ | C27H26FN3OS | 100 MG

R 59-022 is a small-molecule diacylglycerol kinase (DGK) inhibitor used in biochemical and cell-based studies to probe DAG/PKC signaling and lipid metabolism. It also functions as a 5-HT receptor antagonist and activates protein kinase C, potentiating thrombin-induced diacylglycerol production in platelets.

Inhibits diacylglycerol kinase activity (IC50 ~2.8 μM).
Acts as a 5-HT receptor antagonist and activates protein kinase C.
Modulates diacylglycerol and phosphatidic acid metabolism in cells.
High purity suitable for biochemical assays and cell studies.
Offered in solid and solution formats for flexible experimental use.

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1,376

MEDCHEMEXPRESS LLC PH-797804 | 586379-66-0 | 98.9% | 477.30 g·mol⁻¹ | C22H19BrF2N2O3 | 200 MG

PH-797804 is an ATP-competitive, selective inhibitor of p38 mitogen-activated protein kinases (p38α/p38β) used in research to probe p38-mediated signaling and inflammatory responses. It shows nanomolar biochemical potency and demonstrable cellular activity that reduces LPS-induced cytokine production.

Selective ATP-competitive p38α/p38β inhibitor.
Nanomolar biochemical potency (p38α IC50 26 nM; Ki 5.8 nM).
Demonstrated cellular activity reducing LPS-induced TNF-α and IL-1β release.
Does not inhibit JNK2, supporting target selectivity.
High supplied purity and solid white to off-white appearance.
Suitable for biochemical and cellular assay applications.

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1,377

MEDCHEMEXPRESS LLC Daclatasvir | 1009119-64-5 | MFCD18074519 | 98.7% | 738.88 g/mol | C40H50N8O6 | 200 MG

Daclatasvir is a potent NS5A inhibitor used as a research reagent to study hepatitis C virus replication and related pharmacology. The compound shows picomolar-range antiviral activity across multiple HCV genotypes and also inhibits OATP1B and OATP1B3 transporters. It is supplied as a high-purity solid and is commonly provided in solution formats for in vitro assays.

Potent NS5A inhibition with EC50s in the picomolar range.
High purity suitable for biochemical and cellular assays.
Available in multiple pack sizes for small- and large-scale experiments.
Soluble in DMSO and commonly supplied as 10 mM solution for convenience.
Also inhibits OATP1B and OATP1B3, relevant for transporter studies.
Molecular weight 738.88 g/mol for formula-based calculations.

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1,378

MEDCHEMEXPRESS LLC N-[4-[2-ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]benzamide | 303162-79-0 | MFCD17012805 | 99.8% | 399.51 g/mol | C24H21N3OS | 200 MG

TAK-715 is an orally active, potent p38 MAPK inhibitor used in research to probe p38α signaling and related pathways; it also inhibits casein kinase I (CK1δ/ε) and has demonstrated efficacy in preclinical inflammation models.

Potent p38α inhibition (IC50 7.1 nM) with reduced activity against p38β (IC50 200 nM).
Reported inhibition of CK1δ/ε and modulation of Wnt/β-catenin signaling.
Chemical formula C24H21N3OS; molecular weight 399.51 g/mol.
High reported purity (99.76%).
Soluble in DMSO (≈50 mg/mL) with suggested protocols for in vivo formulation.
Powder stable at -20°C for extended storage; solvent stocks stable at -80°C.

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1,379

MEDCHEMEXPRESS LLC TLR7/8 agonist 1 dihydrochloride | 1620278-72-9 | MFCD31657341 | 99.7% | 432.39 | C22H27Cl2N5 | 10 MG

TLR7/8 agonist 1 dihydrochloride is a small-molecule imidazoquinoline research compound that acts as a dual agonist of Toll-like receptors 7 and 8. It is intended for use in immunology and inflammation studies and demonstrates low-nanomolar activity in receptor assays, suitable for both in vitro and in vivo experimental applications.

Dual agonist of TLR7 and TLR8 with low-nanomolar potency.
High reported purity (99.7%).
Molecular weight 432.39 and formula C22H27Cl2N5.
High solubility in DMSO (83.33 mg/mL) and compatible with common in vivo vehicles.
Supplied as an off-white to light yellow solid and available as a DMSO solution.
Storage: 4°C sealed; in solvent store at -80°C for long term.

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1,380

MEDCHEMEXPRESS LLC Stiripentol | 49763-96-4 | MFCD00869310 | >=98.0% | 234.29 g/mol | C14H18O3 | 200 MG

Stiripentol is an anticonvulsant research compound used as adjunct therapy in seizure disorders such as Dravet syndrome. This product listing represents a 200 mg research reagent with analytical identifiers and purity information available from supplier and reference databases.

High purity ≥98.0% (HPLC).
Molecular formula C14H18O3.
Molecular weight 234.29 g/mol.
Pack contains 200 mg of compound.
For research use only.

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Quinolines and derivatives

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MEDCHEMEXPRESS LLC Bosutinib hydrate | 918639-08-4 | MFCD29920031 | 100.0% | 548.46 g/mol | C26H31Cl2N5O4 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC Luminespib | 747412-49-3 | MFCD14635361 | 99.8% | 465.54 | C26H31N3O5 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC Trovafloxacin mesylate | 147059-75-4 | MFCD00913361 | 99.8% | 512.46 g/mol | C21H19F3N4O6S | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC Trovafloxacin mesylate | 147059-75-4 | MFCD00913361 | 99.8% | 512.46 g/mol | C21H19F3N4O6S | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC 3-Thiazolidinepropanoic acid, 5-(5-chloro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo- | 1426138-42-2 | 98.0% | 368.82 g/mol | C14H9ClN2O4S2 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC Ruboxistaurin mesylate | 192050-59-2 | 99.9% | 564.65 g/mol | C29H32N4O6S | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC Acridine orange (hydrochloride) | 65-61-2 | MFCD00150070 | 99.7% | 301.81 g/mol | C17H20ClN3 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC SLF-amido-C2-COOH 10mg | 1092369-24-8 | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC PH-797804 | 586379-66-0 | 98.9% | 477.30 g·mol⁻¹ | C22H19BrF2N2O3 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC Daclatasvir | 1009119-64-5 | MFCD18074519 | 98.7% | 738.88 g/mol | C40H50N8O6 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC N-[4-[2-ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]benzamide | 303162-79-0 | MFCD17012805 | 99.8% | 399.51 g/mol | C24H21N3OS | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC TLR7/8 agonist 1 dihydrochloride | 1620278-72-9 | MFCD31657341 | 99.7% | 432.39 | C22H27Cl2N5 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC Stiripentol | 49763-96-4 | MFCD00869310 | >=98.0% | 234.29 g/mol | C14H18O3 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More