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Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.
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TNF-α (31-45), human is a potent NF-kB pathway activator and a proinflammatory cytokine that induces necrosis or apoptosis. It stimulates the NF-κB pathway via TNFR2, promoting cancer growth, invasion, and metastasis.
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This Azido-PEG11-amine is a chemical compound with the molecular formula C24H50N4O11 and a molecular weight of 570.67. It appears as a colorless to light yellow liquid with a purity of at least 98.0%. This product is suitable for various laboratory applications.
Colorless to light yellow liquid appearance
Molecular weight of 570.67
Purity of at least 98.0%
Consistent with structure by 1H NMR Spectrum
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Azido-PEG11-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an azide group and an amine group. The product appears as a colorless to light yellow liquid and is intended for research use only, not for medical applications.
PEG-based PROTAC linker
Click chemistry reagent
Contains an azide group and an amine group
Colorless to light yellow liquid
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Cinchonidine (CAS 485-71-2) is a small-molecule inhibitor targeting the serotonin transporter (SERT) It is designed to inhibit SERT function thereby modulating serotonin uptake activity Cinchonidine exerts its biological activity primarily through SERT inhibition In in vitro studies Cinchonidine demonstrates inhibitory activity with IC50 values of 330 M for dSERT and 4 2 36 196 and 15 M for hSERT and its mutants I172M S438T and Y95F respectively Based on these pharmacological properties Cinchonidine holds research potential in serotonin transporter regulation and malaria research
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