Tetrapyrroles and derivatives
Abcam (R)-CPP (mM/ml), NMDA antagonist, 10MM_ML
MW 252.2 Da. Highly potent, competitive NMDA antagonist; more active enantiomer of (RS)-CPP (ab120160). (Ki values are 0.04, 0.3, 0.6 and 2.0 μM at NR1/NR2A, NR1/NR2B, NR1/NR2C and NR1/NR2D, respectively).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Monosodium urate (PBS solution), NLRP3/NALP3 inflammasome activator, 10MG
MW 190.09 Da. NLRP3/NALP3 inflammasome activator. Stimulates caspase-1 activating NLRP3/NALP3 inflammasome, results in active IL-1β and IL-18 production. Active in vitro and in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam PDTC (Ammonium pyrrolidinedithiocarbamate), NF-kappaB inhibitor antio x idant, 100MG
MW 164.3 Da. Selective NF-κB inhibitor. Inhibits translation of nitric oxide synthase mRNA to prevent induction. Metal ion chelator and antioxidant. Active in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Nafadotride, D3 antagonist, 50MG
MW 365.5 Da, Purity >99%. Potent, selective D3 antagonist (Ki values are 0.52 nM (D3), 269 nM (D4) and 5 nM (D2)).
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB 216641 hydrochloride, h5-HT1B antagonist, 50MG
MW 523.03 g/mol, Purity >98%. Selective h5-HT₁B receptor antagonist. 25-fold selectivity over h5-HT₁D. Little or no affinity for a range of other receptor subtypes.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Edaravone (MCI-186), antio x idant, 50MG
MW 174.2 Da, Purity >99%. Free radical scavenger and potent antioxidant. Inhibits production of reactive oxygen species, apoptosis and the lipoxygenase system.
The product is subject to the following: Abcam Restricted Use Statement
Abcam ODQ, NO-sensitive guanylyl cyclase inhibitor, 10MG
MW 187.15 Da, Purity >99%. Selective, potent inhibitor of nitric oxide-sensitive guanylyl cyclase. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam L-cis-Diltiazem, cyclic nucleotide-gated channel blocker, 5MG
MW 451 Da, Purity >97%. Selective inhibitor of cyclic nucleotide-gated (CNG) channels. Blocks rod-type CNGA1, olfactory-type CNGA2 and cone-type CNGA3, at micromolar concentrations. Optical isomer of diltiazem (ab120260). Protects against myocardial dysfunction in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Aobchem 1 1-Dimethylethyl 3-(4-chlorophenyl)-2-cyano-2-propenoate | 95% | CAS 883024-88-2 | C14H14ClNO2 | 5g
1 1-Dimethylethyl 3-(4-chlorophenyl)-2-cyano-2-propenoate | 95% | CAS 883024-88-2 | C14H14ClNO2 | 5g
Abcam MPEP hydrochloride, mGlu5 antagonist, 10MG
MW 229.7 Da, Purity >99%. Subtype selective and potent non-competitive mGlu₅ antagonist (IC₅₀ = 36 nM). Central effects following systemic administration in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Undecylprodigiosin, Apoptotic and anticancer agent, 250UG
MW 393.6 Da, Purity >93%. Apoptotic and anticancer agent. Selectively induces p53-independant apoptosis in cancer cells. Induces G2/M cell cycle arrest and shows antiproliferative effects. Shows antimalarial and antibactieral effects in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam AR 231453, GPR119 agonist, 5MG
MW 505.5 Da, Purity >99%. Potent, selective G-protein coupled receptor 119 (GPR119) agonist (EC₅₀ = 0.68 nM). Enhances glucose-induced insulin release. Antidiabetic activity. Orally active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam GBR 12909 dihydrochloride, Dopamine transport inhibitor, 10MG
MW 523.5 Da, Purity >98%. Potent, selective dopamine reuptake inhibitor (IC₅₀ = 2.32 μM in rat hippocampal slices; IC₅₀ = 6-35 μM in whole cell patch clamp recordings).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Desmethyl YM298198 hydrochloride, Analogue of mGlu1 antagonist YM298198, 10MG
MW 364.9 Da, Purity >99%. Derivative of mGlu1 antagonist YM298198 (ab120015). Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Rotigotine hydrochloride, Dopamine receptor agonist, 10MG
MW 351.93 g/mol, Purity >99%. Dopamine receptor agonist. High affinity for D₁, D₂ and D₃ receptors (Ki values are 83, 13 and 0.71 nM, respectively). Shows significant affinity at α₂B and 5-HT₁A receptors (Ki values are 27 and 30 nM, respectively). Exhibits anti-Parkinsonian and antidepressant activity.
The product is subject to the following: Abcam Restricted Use Statement