Tetrapyrroles and derivatives
Abcam ENMD-1068, protease-activated receptor 2 (PAR2) anatagonist, 5MG
MW 283.41 Da, Purity >99%. Selective protease-activated receptor 2 (PAR2) antagonist (IC₅₀ = 1.2 mM). Anti-inflamatory agent. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Abcam QNZ, NF-kB inhibitor, 1MG
MW 358.4 Da, Purity >98%. Potent, selective NF-kB inhibitor (IC₅₀ = 11 nM). Inhibits LPS-induced TNFα production (IC₅₀ = 7 nM). Reduces edema in inflammation in vivo..
The product is subject to the following: Abcam Restricted Use Statement
Abcam Endothelin-1 (human, porcine), Vasoconstrictor peptide, 10UG
MW 2491.9 Da. Endothelin-1 (human, porcine), Vasoconstrictor peptide. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Sigma Aldrich Fine Chemicals Biosciences Coenzyme B12 >=97.0% | 13870-90-1 | MFCD00135609 | 1G
Coenzyme B12 >=97.0% | Purity: >=97.0% | Mol Wt: 1579.58 | 13870-90-1 | MFCD00135609 | 1G
Medchemexpress LLC Biotin-Vitamin B12 (Biotin-Cyanocobalamin B12) | 98.4% | 5 MG
Biotin-Vitamin B12 (Biotin-Cyanocobalamin B12) is a biotinylated form of Vitamin B12, crucial for brain and nervous system function, and blood formation. It protects against oxidative stress and aids in inflammatory diseases. Involved in cellular metabolism, DNA synthesis, fatty acid synthesis, and energy production, it is valuable for research into vitamin B12 transport, cellular uptake, targeted delivery, and analytical detection.
- Biotinylated vitamin B12
- Supports brain and nervous system function
- Essential for blood formation
- Protects against oxidative-stress-associated pathologies
- Beneficial in inflammatory diseases
- Involved in cellular metabolism, DNA synthesis, and energy production
- Facilitates research on vitamin B12 transport and cellular uptake
- Supports targeted delivery and analytical detection research
Medchemexpress LLC Protoporphyrin IX (Standard) | 553-12-8 | 96.1% | 50 MG
Protoporphyrin IX (Standard) serves as an analytical reference standard for diverse research and analytical applications. It functions as a key intermediate in the heme biosynthetic pathway, acting as both a radiation sensitizer-boosting reactive oxygen species (ROS) generation and inducing DNA damage even in hypoxic states-and a photosensitizer, undergoing photobleaching upon light exposure.
- Enhances ROS generation and induces DNA damage.
- Undergoes photobleaching through direct degradation by light irradiation.
- Accumulates in tumor cells after 5-aminolevulinic acid (5-ALA) administration.
- Causes selective improvement of basal cell carcinoma when activated by red fluorescence.
- Promising for research into sonodynamic and photodynamic agents for various cancers.
- Used in qualitative, quantitative, and methodological research experiments.
- Ideal for applications in HPLC, GC, and MS.
Sigma Aldrich Fine Chemicals Biosciences Cytochrome c from equine heart | 9007-43-6 | MFCD00130890 | 10 mg
Cytochrome c from equine heart | Purity: ≥99% | Mol Wt: 12,384 | 9007-43-6 | MFCD00130890 | 10 mg
Abcam TPEN, Metal ion chelator, 100MG
MW 424.5 Da, Purity >99%. Metal ion chelator. Decreases intracellular zinc levels. Induces apoptosis. Causes defects in oocyte maturation. Modulates hippocampal neurogenesis following seizure. Cell permeable. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Chlorin e6 trisodium | 72984-36-2 | 98.7% | 662.62 | C34H33N4Na3O6 | 5mg
Chlorin e6 Ce6 (trisodium) is a water-soluble derivative of chlorophyll belonging to the chlorin class of photosensitizers with an absorption wavelength range of 600-670 nm Chlorin e6 trisodium emits characteristic red fluorescence upon light excitation enabling real-time identification of tumor boundaries and progression Chlorin e6 trisodium can be used for the study of photodynamic therapy (PDT) of cancers (bladder cancer) and fluorescence diagnosis of neoplastic lesions[1][2][3]
Abcam TC-2403 o x alate, alpha4beta2 nAChR selective agonist, 50MG
MW 252.27 g/mol, Purity >99%. High affinity α4β2 nAChR selective agonist (Ki = 26 nM). Selective for CNS nAChR over muscle, ganglionic or enteric ACh receptors (EC₅₀ = 732 nM in rat thalamic synaptosomes).
The product is subject to the following: Abcam Restricted Use Statement
Abcam AR 231453, GPR119 agonist, 25MG
MW 505.5 Da, Purity >99%. Potent, selective G-protein coupled receptor 119 (GPR119) agonist (EC₅₀ = 0.68 nM). Enhances glucose-induced insulin release. Antidiabetic activity. Orally active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB 243213 dihydrochloride, 5HT2C receptor antagonist, 10MG
MW 464.9 Da, Purity >99%. Potent, selective 5-HT2C receptor antagonist (Ki = 1 nM). Neurological agent. Active *in vivo* and *in vitro*.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB 243213 dihydrochloride, 5HT2C receptor antagonist, 50MG
MW 464.9 Da, Purity >99%. Potent, selective 5-HT2C receptor antagonist (Ki = 1 nM). Neurological agent. Active *in vivo* and *in vitro*.
The product is subject to the following: Abcam Restricted Use Statement
Abcam MPEP hydrochloride, mGlu5 antagonist, 50MG
MW 229.7 Da, Purity >99%. Subtype selective and potent non-competitive mGlu₅ antagonist (IC₅₀ = 36 nM). Central effects following systemic administration in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Ibotenic acid, e x citoto x ic agonist, 25MG
MW 158.11 Da, Purity >98%. Neuroexcitatory amino acid originally isolated from Amanita species. Neurotoxin often used to model cognitive dysfunctions. NMDA and metabotropic receptor agonist.
The product is subject to the following: Abcam Restricted Use Statement