Tetrapyrroles and derivatives
Aobchem 2-Propynoic acid 3-(4-chlorophenyl)- ethyl ester | ≥97% | CAS 20026-96-4 | C11H9ClO2 | 1g
2-Propynoic acid 3-(4-chlorophenyl)- ethyl ester | ≥97% | CAS 20026-96-4 | C11H9ClO2 | 1g
eMolecules 148471-91-4 | Medchem Express | Hematoporphyrin monomethyl ether | 5mg | 705860738 | HY-134990 | 1225.454 | C70H80N8O12
Medchem Express | A-674563 (hydrochloride) | 5mg | 446262573 | HY-13254A | 2070009-66-2 | MFCD18711680 | 394.900 | C22H23ClN4O
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Apexbio Technology LLC Chlorin e6(Synonyms: Ce6, Chlorophyllin e6, Chlorophyll derivative e6, Chlorin-e6, Chlorin e-6), 500mg, CAS: 19660-77-6.
Chlorin e6 (Ce6 CAS 19660-77-6) is a second-generation photosensitizer utilized in photodynamic therapy (PDT) research with demonstrated anticancer activity when activated by laser irradiation Upon irradiation Ce6 generates reactive oxygen species mediating cytotoxic effects and cellular apoptosis In mouse models intravenous administration of Ce6 (2 5 10 mg/kg) combined with irradiation (50 200 J/cm ) resulted in complete elimination of implanted fibrosarcomas In clinical trials for bronchogenic superficial squamous cell carcinoma Ce6-based PDT (40 mg/m 100 J/cm ) produced complete response rates up to 82 9% underscoring its utility for cancer therapy studies
eMolecules 14643-66-4 | Medchem Express | Coproporphyrin III | 1mg | 446256752 | HY-101398 | 654.72 | C36H38N4O8
Ambeed | (9-Oxo-9H-fluoren-2-yl)boronic acid | 250mg | 721299020 | A1618029 | 2036064-15-8 | 224.020 | C13H9BO3
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eMolecules 19444-84-9 | Ambeed | 3-Hydroxydihydrofuran-2(3H)-one | 1g | 525145111 | A237190 | MFCD00134268 | 102.089 | C4H6O3
Medchem Express | (Z)-Thiothixene | 5mg | 446259291 | HY-108324 | 3313-26-6 | MFCD00079574 | 443.620 | C23H29N3O2S2
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Enzo Life Sciences Protoporphyrin IX (free acid) (300mg). CAS: 553-12-8
Protoporphyrin IX free acid, as distinct from its zinc salt (which inhibits heme oxygenase), activates soluble guanylyl cyclase (sGC) by binding directly to the enzyme. A useful reagent in cases where the use of nitric oxide (NO) or nitric oxide donors is undesirable. Alternative name: 8,13-Divinyl-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid. Purity: ≥95% (HPLC). Solubility: Dissolve initially in 0.1M base (Tris base or NaOH), then add water miscible organic solvent (EtOH (10mg/ml), MeOH, DMSO (10mg/ml), DMF) until solution is 50/50 base/solvent. When a clear solution is obtained, it can be diluted into an aqueous medium and titrated or buffered to any pH>7. Use immediately. Long Term Storage: -20°C.
Cayman Chemical Mn(III) Protoporphyrin IX Chloride, Purity: ≥95%, CAS: 120389-54-0, 100 mg
A metalloporphyrin; induces mRNA expression of the genes encoding δ-aminolevulinate synthase and HO in chick embryo liver cells at 10 µM; manganese(III) protoporphyrin IX chloride-containing nanobialys have been used in MRI of fibrin clots in vitro; has been used in the synthesis of MnGGH
Selleck Chemical LLC Protoporphyrin IX (PPIX) S5145-25mg
Protoporphyrin IX (PPIX) is a heterocyclic organic compound which consists of four pyrrole rings and is the final intermediate in the heme biosynthetic pathway
eMolecules 42417-39-0 | 3-Aminodihydrofuran-2(3H)-one hydrochloride | MFCD27977179 | 1g
Ambeed | 5-Ethoxy-1H-indole-2-carboxylic acid | 250mg | 632809689 | A591873 | 93476-60-9 | MFCD02664445 | 205.213 | C11H11NO3
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Medchemexpress LLC Chlorin e6 trimethyl ester | 35038-32-5 | MFCD09838560 | 99.8% | 638.75 | C37H42N4O6 | 5 MG
Chlorin e6 trimethyl ester is a methyl pheophorbide-A derivative photosensitizer used in photodynamic therapy research and photophysics studies. It is supplied as a high-purity solid for in-vitro use and formulation, with defined solubility and storage recommendations to preserve stability.
- High reported purity (99.8%) suitable for research applications.
- Photosensitizer used in photodynamic therapy and photophysics studies.
- Soluble in DMSO at about 10 mg/mL with sonication and warming to 60°C; hygroscopic DMSO can affect solubility.
- Powder storage: -20°C (up to 3 years) or 4°C (up to 2 years); in solvent: -80°C (6 months) or -20°C (1 month).
- Provided as a brown to black solid appropriate for formulation and analytical work.
Apexbio Technology LLC Chlorin e6(Synonyms: Ce6, Chlorophyllin e6, Chlorophyll derivative e6, Chlorin-e6, Chlorin e-6), 100mg, CAS: 19660-77-6.
Chlorin e6 (Ce6 CAS 19660-77-6) is a second-generation photosensitizer utilized in photodynamic therapy (PDT) research with demonstrated anticancer activity when activated by laser irradiation Upon irradiation Ce6 generates reactive oxygen species mediating cytotoxic effects and cellular apoptosis In mouse models intravenous administration of Ce6 (2 5 10 mg/kg) combined with irradiation (50 200 J/cm ) resulted in complete elimination of implanted fibrosarcomas In clinical trials for bronchogenic superficial squamous cell carcinoma Ce6-based PDT (40 mg/m 100 J/cm ) produced complete response rates up to 82 9% underscoring its utility for cancer therapy studies
Medchemexpress LLC Chlorin e6 trisodium | 72984-36-2 | 98.7% | 662.62 | C34H33N4Na3O6 | 5mg
Chlorin e6 Ce6 (trisodium) is a water-soluble derivative of chlorophyll belonging to the chlorin class of photosensitizers with an absorption wavelength range of 600-670 nm Chlorin e6 trisodium emits characteristic red fluorescence upon light excitation enabling real-time identification of tumor boundaries and progression Chlorin e6 trisodium can be used for the study of photodynamic therapy (PDT) of cancers (bladder cancer) and fluorescence diagnosis of neoplastic lesions[1][2][3]
Frontier Specialty Chemicals 100mg 5-Mono(4-carboxyphenyl)-10,15,20-triphenyl porphine, 95051-10-8 MFCD01366156
5-Mono(4-carboxyphenyl)-10,15,20-triphenyl porphine CAS: 95051-10-8 MFCD01366156 Porphyrins Synthetic Porphyrins
Apexbio Technology LLC Chlorin e6(Synonyms: Ce6, Chlorophyllin e6, Chlorophyll derivative e6, Chlorin-e6, Chlorin e-6), 50mg, CAS: 19660-77-6.
Chlorin e6 (Ce6 CAS 19660-77-6) is a second-generation photosensitizer utilized in photodynamic therapy (PDT) research with demonstrated anticancer activity when activated by laser irradiation Upon irradiation Ce6 generates reactive oxygen species mediating cytotoxic effects and cellular apoptosis In mouse models intravenous administration of Ce6 (2 5 10 mg/kg) combined with irradiation (50 200 J/cm ) resulted in complete elimination of implanted fibrosarcomas In clinical trials for bronchogenic superficial squamous cell carcinoma Ce6-based PDT (40 mg/m 100 J/cm ) produced complete response rates up to 82 9% underscoring its utility for cancer therapy studies
Enzo Life Sciences Zinc(II) Protoporphyrin IX (100mg). CAS: 15442-64-5
Potent and selective inhibitor of heme oxygenase (Ki=3nM), the enzyme that generates carbon monoxide (CO). Inhibits soluble guanylyl cyclase. Produces a time- and concentration-dependent inactivation of all three isoforms of nitric oxide synthase (IC50=0.8µM, 4.0µM, and 5.0µM for nNOS (NOS I), iNOS (NOS II) and eNOS (NOS III), respectively). Does not cross the blood-brain barrier. An useful tool to elucidate the role of CO in signal transduction and as a neurotransmitter. Purity: ≥95% (TLC). Appearance: Dark solid. Solubility: Soluble in pyridine, dimethyl formamide or DMSO. Colloidal in aqueous base; slightly soluble in aqueous base/organic solvent mixtures. Long Term Storage: -20°C.