Tetrapyrroles and derivatives
Abcam GBR 12909 dihydrochloride, Dopamine transport inhibitor, 50MG
MW 523.5 Da, Purity >98%. Potent, selective dopamine reuptake inhibitor (IC₅₀ = 2.32 μM in rat hippocampal slices; IC₅₀ = 6-35 μM in whole cell patch clamp recordings).
The product is subject to the following: Abcam Restricted Use Statement
Apexbio Technology LLC Bilirubin 635-65-4 10mM (in 1mL DMSO)
Bilirubin (CAS 635-65-4) is a bile pigment naturally produced from the catabolism of heme It exhibits antioxidant properties primarily via scavenging reactive oxygen species and inhibiting oxidative modification of biomolecules Bilirubin modulates signaling pathways associated with inflammation oxidative stress and cellular apoptosis rendering it relevant in biomedical research focused on hepatic disorders cardiovascular disease and neurodegenerative conditions Originally identified from bezoar bilirubin requires storage under airtight cool and dry conditions to maintain stability
Medchemexpress LLC HY-B0754 100mg Medchemexpress, Hematoporphyrin CAS:14459-29-1 Purity:>98%
Medchemexpress, HY-B0754 100mg Hematoporphyrin CAS:14459-29-1 Hematoporphyrin (Hematoporphyrin IX), a photosensitizer, is a substrate for affinity chromatography of heme-binding proteins. Hematoporphyrin can induce apoptosis in U87 glioma cells and decrease tumor growth in vivo when exposed to red light. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Abcam PNU 282987, alpha7 nAChR agonist, 10MG
MW 301.2 Da, Purity >99%. Selective α7nAChR agonist. Negligible activity at α1β1γδ and α3β4 receptors. High affinity for rat α7nACh receptors (Ki = 26 nM). Functional antagonist at 5-HT₃ receptors (IC₅₀ = 4541 nM).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Verteporfin (Visudyne), Benzoporphyrin derivative, 5MG
MW 718.8 Da, Purity >96%. Benzoporphyrin derivative. Antiangiogenic agent. Produces ROS on stimulation with nonthermal red light in the presence of oxygen. Prevents corneal neovascularization and shows antitumor effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam Pimobendan (Vetmedin), Ca2+ channel sensitizer, 10MG
MW 334.4 Da, Purity >99%. Ca2+ channel sensitizer. Selective PDE3 inhibitor. Inhibits platelet aggregation. Shows antithrombotic, antihypertensive, potent inotropic and vasodilatory effects *in vivo.* Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB 408124, non-peptide O x 1 antagonist, 10MG
MW 356.4 Da, Purity >97%. Selective, non-peptide orexin receptor 1 (OX1) antagonist (Ki = 26.9 nM). Displays 50-fold selectivity over OX2 (Kb values are 21.7 and 1405 nM for OX1 and OX2, respectively).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Pimobendan (Vetmedin), Ca2+ channel sensitizer, 5MG
MW 334.4 Da, Purity >99%. Ca2+ channel sensitizer. Selective PDE3 inhibitor. Inhibits platelet aggregation. Shows antithrombotic, antihypertensive, potent inotropic and vasodilatory effects *in vivo.* Orally active.
The product is subject to the following: Abcam Restricted Use Statement
eMolecules Zinc protoporphyrin | 15442-64-5 | | 1g
Combi-Blocks | Zinc protoporphyrin | 1g | 537622985 | QC-1107 | 95.000 | 15442-64-5 | | 626.030 | C34H32N4O4Zn
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
eMolecules 3-Aminodihydrofuran-2(3H)-one hydrochloride | 42417-39-0 | MFCD27977179 | 1g
Ambeed | 3-Aminodihydrofuran-2(3H)-one hydrochloride | 1g | 525096753 | A179518 | | 42417-39-0 | MFCD27977179 | 137.560 | C4H8ClNO2
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Abcam MPEP hydrochloride, mGlu5 antagonist, 50MG
MW 229.7 Da, Purity >99%. Subtype selective and potent non-competitive mGlu₅ antagonist (IC₅₀ = 36 nM). Central effects following systemic administration in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SEN 12333, alpha7 nicotinic acetylcholine receptor (nAChR) agonist, 10MG
MW 339.4 Da, Purity >98%. Potent, selective α7 nicotinic acetylcholine receptor (nAChR) agonist. High affinity for rat α7 receptors (Ki = 260 nM). Full agonist in functional Ca²+ flux studies (EC₅₀ = 1.6 μM). Active in vivo and in vitro. Excellent brain penetration. Orally bioavailable.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Necrostatin-1, necroptosis inhibitor, 5MG
MW 259.33 Da, Purity >99%. Potent, specific necroptosis inhibitor (EC₅₀ = 490 nM). Selective allosteric inhibitor of death domain receptor-associated adaptor kinase RIP1 in vitro (EC₅₀ = 182 nM). Caspase independent, programmed necrosis pathway.
The product is subject to the following: Abcam Restricted Use Statement