Thienodiazepines
Apexbio Technology LLC Olanzapine 132539-06-1 10mM (in 1mL DMSO)
Olanzapine (CAS 132539-06-1) is a small molecule antagonist with high affinity for serotonin 5-HT2 and dopamine D2 receptors both classified as G protein-coupled receptors (GPCRs) In vitro binding studies demonstrate Olanzapine interacts at nanomolar concentrations with dopaminergic serotonergic 1-adrenergic and muscarinic receptors In vivo Olanzapine antagonizes dopamine and serotonin receptors and exhibits weaker efficacy at -adrenergic and muscarinic sites Administration in animal models increases extracellular dopamine and norepinephrine levels in specific brain regions in a dose-dependent manner Olanzapine is widely utilized in neuropharmacological research to investigate antipsychotic mechanisms
Apexbio Technology LLC Olanzapine 132539-06-1 1g
Olanzapine (CAS 132539-06-1) is a small molecule antagonist with high affinity for serotonin 5-HT2 and dopamine D2 receptors both classified as G protein-coupled receptors (GPCRs) In vitro binding studies demonstrate Olanzapine interacts at nanomolar concentrations with dopaminergic serotonergic 1-adrenergic and muscarinic receptors In vivo Olanzapine antagonizes dopamine and serotonin receptors and exhibits weaker efficacy at -adrenergic and muscarinic sites Administration in animal models increases extracellular dopamine and norepinephrine levels in specific brain regions in a dose-dependent manner Olanzapine is widely utilized in neuropharmacological research to investigate antipsychotic mechanisms
![Medchemexpress LLC 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b]benzodiazepine | 132539-06-1 | MFCD00866702 | 100.0% | 312.43 | C17H20N4S | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000221618.png-250.jpg)
Medchemexpress LLC 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b]benzodiazepine | 132539-06-1 | MFCD00866702 | 100.0% | 312.43 | C17H20N4S | 5 MG
Analytical reference standard of olanzapine for research and analytical applications. Olanzapine is an atypical antipsychotic that acts as a monoaminergic antagonist with high affinity for multiple serotonin and dopamine receptors. This standard is intended for qualitative, quantitative, and methodological workflows including HPLC, GC, and MS and is supplied with a certificate of analysis.
- High purity suitable for analytical use.
- Solid, light yellow to yellow appearance.
- Intended for HPLC, GC, and MS applications.
- Supplied in multiple small pack sizes for reference work.
- Certificate of analysis included for storage and handling instructions.
Medchemexpress LLC Olanzapine N-oxide | 174794-02-6 | 98.0% | 10 MG
Olanzapine N-oxide is a drug metabolite and research compound used to study the metabolism and analytical profiling of olanzapine. It is supplied as a solid powder with supporting characterization data for laboratory and in vitro research.
- Provided as a solid powder for analytical and in vitro studies.
- High purity (98.0%) suitable for analytical applications.
- Available in small-scale sizes, including 10 mg.
- Characterized by COA, HNMR, LCMS, and RP-HPLC documentation.
- Stable when stored under recommended conditions (powder: -20°C or 4°C).
Medchemexpress LLC Olanzapine (standard) | 132539-06-1 | MFCD00866702 | 99.96% | C17H20N4S | 10MG
Olanzapine (Standard) is an analytical reference standard of the atypical antipsychotic olanzapine provided for research and analytical use. It is intended for method development, calibration, and qualitative or quantitative analysis by techniques such as HPLC, GC, and mass spectrometry. Users should consult the certificate of analysis (COA) for lot-specific purity and test results.
- Analytical reference standard suitable for method development and validation.
- Intended for HPLC, GC, and MS qualitative and quantitative analysis.
- High reported purity (product listing ≈99.96%); verify lot COA for exact value.
- Provided in small, accurately weighed quantities for calibration use.
- Includes documentation such as COA and SDS for regulatory and safety compliance.
